Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer (Q38052818)

27 August 2017

Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer (English)

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27 August 2017

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Melis Kartal Yandım

1

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27 August 2017

Elif Apohan

series ordinal

2

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27 August 2017

Yusuf Baran

series ordinal

3

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27 August 2017

17 October 2012

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Cancer Chemotherapy and Pharmacology

27 August 2017

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27 August 2017

71

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27 August 2017

13-20

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27 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s00280-012-1984-x

27 August 2017

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Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas

21 January 2018

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Importance of cytochrome c redox state for ceramide-induced apoptosis of human mammary adenocarcinoma cells

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21 January 2018

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Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells

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Differences in the domain forming properties of N-palmitoylated neutral glycosphingolipids in bilayer membranes

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The cell biology of glycosphingolipids.

21 January 2018

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The total syntheses of D-erythro-sphingosine, N-palmitoylsphingosine (ceramide), and glucosylceramide (cerebroside) via an azidosphingosine analog

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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GCS induces multidrug resistance by regulating apoptosis-related genes in K562/AO2 cell line

21 January 2018

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P-glycoprotein is implicated in the inhibition of ceramide-induced apoptosis in TF-1 acute myeloid leukemia cells by modulation of the glucosylceramide synthase pathway

21 January 2018

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The involvement of sphingolipids in multidrug resistance

21 January 2018

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Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

21 January 2018

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Ceramide glycosylation potentiates cellular multidrug resistance

21 January 2018

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Accumulation of glucosylceramides in multidrug-resistant cancer cells

21 January 2018

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Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells

21 January 2018

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A role for ceramide in driving cancer cell resistance to doxorubicin.

21 January 2018

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Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer

21 January 2018

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Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: in vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells

21 January 2018

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A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis

21 January 2018

1 reference

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Targeting glucosylceramide synthase downregulates expression of the multidrug resistance gene MDR1 and sensitizes breast carcinoma cells to anticancer drugs

21 January 2018

1 reference

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Co-suppression of MDR1 (multidrug resistance 1) and GCS (glucosylceramide synthase) restores sensitivity to multidrug resistance breast cancer cells by RNA interference (RNAi).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Targeting glucosylceramide synthase sensitizes imatinib-resistant chronic myeloid leukemia cells via endogenous ceramide accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Sphingolipid metabolism enzymes as targets for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Rationales for cancer chemotherapy with PDMP, a specific inhibitor of glucosylceramide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Chemotherapy by slowing glucosphingolipid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

PDMP sensitizes neuroblastoma to paclitaxel by inducing aberrant cell cycle progression leading to hyperploidy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

The roles of bioactive sphingolipids in resveratrol-induced apoptosis in HL60: acute myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Resveratrol triggers apoptosis through regulating ceramide metabolizing genes in human K562 chronic myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Roles of ceramide synthase and ceramide clearence genes in nilotinib-induced cell death in chronic myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; ceramide synthase and ceramide clearance genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Bioactive sphingolipids in docetaxel-induced apoptosis in human prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Glucosylceramide synthase inhibition enhances vincristine-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

Overexpression of glucosylceramide synthase in associated with multidrug resistance of leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1984-X

10.1007/S00280-012-1984-X

21 January 2018

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27 August 2017

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