Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal? (Q38051015)

27 August 2017

title

Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal? (English)

1 reference

27 August 2017

1 reference

Hannah R Wardill

1

1 reference

27 August 2017

Joanne M Bowen

series ordinal

2

1 reference

27 August 2017

Rachel J Gibson

series ordinal

3

1 reference

27 August 2017

publication date

30 September 2012

1 reference

Cancer Chemotherapy and Pharmacology

27 August 2017

published in

1 reference

27 August 2017

volume

70

1 reference

27 August 2017

issue

5

1 reference

27 August 2017

page(s)

627-635

1 reference

The pathobiology of mucositis

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Updated clinical practice guidelines for the prevention and treatment of mucositis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Use of the 13C-sucrose breath test to assess chemotherapy-induced small intestinal mucositis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Serum levels of NFkappaB and pro-inflammatory cytokines following administration of mucotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

The role of pro-inflammatory cytokines in cancer treatment-induced alimentary tract mucositis: pathobiology, animal models and cytotoxic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal barrier function: molecular regulation and disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Prospective evaluation of gut mucosal barrier injury following various myeloablative regimens for haematopoietic stem cell transplant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Measuring mucosal damage induced by cytotoxic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Effect of chemotherapy with 5-fluorouracil on intestinal permeability and absorption in patients with advanced colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Alterations in intestinal permeability following the intensified polydrug-chemotherapy IFADIC (ifosfamide, Adriamycin, dacarbazine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability in patients with chemotherapy-induced stomatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability, leaky gut, and intestinal disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Crosstalk of tight junction components with signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Ecological and evolutionary forces shaping microbial diversity in the human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability in the assessment of intestinal toxicity of cytotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Regulation of the movement of solutes across tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

The structure and regulation of tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Tumor necrosis factor alpha disrupts tight junction assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Regulation of tight junction permeability by intestinal bacteria and dietary components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Epithelial transport and barrier function in occludin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

PKC eta regulates occludin phosphorylation and epithelial tight junction integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Lessons learned from the irinotecan metabolic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability and vitamin A absorption in patients with chemotherapy-induced diarrhea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Irinotecan injures tight junction and causes bacterial translocation in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Cytokine regulation of tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability and irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Epithelial tight junctions in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Regulation of airway tight junctions by proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Interleukin-6 changes tight junction permeability and intracellular phospholipid content in a human enterocyte cell culture model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

The tight junction in inflammatory disease: communication breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Long-term effects of tumor necrosis factor on LLC-PK1 transepithelial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Paracrine mediators of mouse uterine epithelial cell transepithelial resistance in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Synergistic effects of interferon gamma and tumour necrosis factor alpha on T84 cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

The biologic role for nuclear factor-kappaB in disease and its potential involvement in mucosal injury associated with anti-neoplastic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Interleukin-6 causes endothelial barrier dysfunction via the protein kinase C pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Vibrio cholerae hemagglutinin/protease (HA/protease) causes morphological changes in cultured epithelial cells and perturbs their paracellular barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Faecal microflora and beta-glucuronidase expression are altered in an irinotecan-induced diarrhea model in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Enteropathogenic Escherichia coli infection leads to appearance of aberrant tight junctions strands in the lateral membrane of intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

CaCo-2 cells treated with Clostridium perfringens enterotoxin form multiple large complex species, one of which contains the tight junction protein occludin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Intestinal permeability: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Chemotherapy for cancer causes apoptosis that precedes hypoplasia in crypts of the small intestine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Zonula Occludens-1 alterations and enhanced intestinal permeability in methotrexate-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Oxidative stress and enhanced paracellular permeability in the small intestine of methotrexate-treated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Methotrexate modulates tight junctions through NF-κB, MEK, and JNK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-012-1989-5

10.1007/S00280-012-1989-5

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1012531514

0 references

1 reference