A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects (Q38048237)

27 August 2017

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects (English)

1 reference

27 August 2017

Diana M Juriloff

1

1 reference

PubMed ID

23024041

27 August 2017

Muriel J Harris

series ordinal

2

1 reference

PubMed ID

23024041

27 August 2017

language of work or name

1 reference

28 September 2012

1 reference

Birth Defects Research Part A: Clinical and Molecular Teratology

27 August 2017

1 reference

27 August 2017

94

1 reference

27 August 2017

10

1 reference

27 August 2017

824-840

1 reference

Role of the planar cell polarity gene CELSR1 in neural tube defects and caudal agenesis

27 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Pointing in the right direction: new developments in the field of planar cell polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Identification and characterization of novel rare mutations in the planar cell polarity gene PRICKLE1 in human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Polygenic inheritance and common diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse: use of microsatellite DNA markers to identify embryonic genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Dishevelled: linking convergent extension with neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The genetic basis of mammalian neurulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

FZD6 is a novel gene for human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Analysis of the planar cell polarity gene Vangl2 and its co-expressed paralogue Vangl1 in neural tube defect patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Principles of planar polarity in animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Development of the vertebrate central nervous system: formation of the neural tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Frizzled6 controls hair patterning in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Development of the cerebellar defect in ataxic SELH/Bc mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Getting to the heart of planar cell polarity signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Prevalence of craniorachischisis in a Texas-Mexico border population

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mouse models for neural tube closure defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Novel mutations in VANGL1 in neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Contribution of VANGL2 mutations to isolated neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mutations in VANGL1 associated with neural-tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

VANGL2 mutations in human cranial neural-tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

An essential role for frizzled 5 in mammalian ocular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Finding the missing heritability of complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Genetic epidemiology of birth defects: nonsyndromic cleft lip and neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The relationship between sonic Hedgehog signaling, cilia, and neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Regulation of planar cell polarity by Smurf ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Wnt5a functions in planar cell polarity regulation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Glossary of Genetics and Cytogenetics – Classical and Molecular

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Cdx mediates neural tube closure through transcriptional regulation of the planar cell polarity gene Ptk7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Recurrence risks for neural tube defects in siblings of patients with lipomyelomeningocele.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Identification of novel rare mutations of DACT1 in human neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Planar cell polarity signaling: from fly development to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Genetic interaction between members of the Vangl family causes neural tube defects in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Spinal dysraphism: a review of neuroradiological features with embryological correlations and proposal for a new classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Dishevelled controls cell polarity during Xenopus gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Neural tube closure requires Dishevelled-dependent convergent extension of the midline

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Reversal of left-right asymmetry: a situs inversus mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

The rodent Four-jointed ortholog Fjx1 regulates dendrite extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.23079

21 January 2018

Identifiers

DOI

10.1002/BDRA.23079

1 reference

27 August 2017

1 reference

PubMed ID

23024041