Viral latency drives 'memory inflation': a unifying hypothesis linking two hallmarks of cytomegalovirus infection (Q38044678)

27 August 2017

Viral latency drives 'memory inflation': a unifying hypothesis linking two hallmarks of cytomegalovirus infection (English)

1 reference

27 August 2017

0 references

1 reference

Kai A Kropp

6

0 references

Matthias J Reddehase

object named as

Matthias J Reddehase

10

0 references

author name string

Christof K Seckert

1

1 reference

27 August 2017

Marion Griessl

2

1 reference

27 August 2017

Julia K Büttner

3

1 reference

27 August 2017

Sabine Scheller

4

1 reference

27 August 2017

Christian O Simon

5

1 reference

27 August 2017

Angélique Renzaho

7

1 reference

27 August 2017

Birgit Kühnapfel

8

1 reference

27 August 2017

Natascha K A Grzimek

9

1 reference

27 August 2017

19 September 2012

1 reference

Medical Microbiology and Immunology

27 August 2017

1 reference

27 August 2017

201

1 reference

27 August 2017

4

1 reference

27 August 2017

551-566

1 reference

https://scigraph.springernature.com/pub.10.1007/s00430-012-0273-y

27 August 2017

0 references

cites work

Mouse models of cytomegalovirus latency: overview

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

A model for reactivation of CMV from latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

The conditions of primary infection define the load of latent viral genome in organs and the risk of recurrent cytomegalovirus disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Hematopoietic stem cell transplantation with latently infected donors does not transmit virus to immunocompromised recipients in the murine model of cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Single cell detection of latent cytomegalovirus reactivation in host tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Liver sinusoidal endothelial cells are a site of murine cytomegalovirus latency and reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

An inquiry into the mechanisms of herpes simplex virus latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

The major virus-producing cell type during murine cytomegalovirus infection, the hepatocyte, is not the source of virus dissemination in the host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Shedding light on the elusive role of endothelial cells in cytomegalovirus dissemination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Human cytomegalovirus latency-associated protein pORF94 is dispensable for productive and latent infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Prevention and treatment of cytomegalovirus pneumonia in transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Murine model of interstitial cytomegalovirus pneumonia in syngeneic bone marrow transplantation: persistence of protective pulmonary CD8-T-cell infiltrates after clearance of acute infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Pulmonary cytomegalovirus reactivation causes pathology in immunocompetent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Random, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalovirus latency in the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Murine cytomegalovirus major immediate-early enhancer region operating as a genetic switch in bidirectional gene pair transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Bidirectional gene organization: a common architectural feature of the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

An abundance of bidirectional promoters in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Murine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Expression of an altered ribonucleotide reductase activity associated with the replication of murine cytomegalovirus in quiescent fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Transactivation of cellular genes involved in nucleotide metabolism by the regulatory IE1 protein of murine cytomegalovirus is not critical for viral replicative fitness in quiescent cells and host tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Elimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Murine cytomegalovirus IE2, an activator of gene expression, is dispensable for growth and latency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

The IE2 promoter/enhancer region from mouse CMV provides high levels of therapeutic protein expression in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Synergism between the components of the bipartite major immediate-early transcriptional enhancer of murine cytomegalovirus does not accelerate virus replication in cell culture and host tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Enhancerless cytomegalovirus is capable of establishing a low-level maintenance infection in severely immunodeficient host tissues but fails in exponential growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Single cell analysis: the new frontier in 'omics'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Integrated microfluidic bioprocessor for single-cell gene expression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Immune evasion proteins enhance cytomegalovirus latency in the lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Allogeneic transplantation induces expression of cytomegalovirus immediate-early genes in vivo: a model for reactivation from latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Lipopolysaccharide, tumor necrosis factor alpha, or interleukin-1beta triggers reactivation of latent cytomegalovirus in immunocompetent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Two antigenic peptides from genes m123 and m164 of murine cytomegalovirus quantitatively dominate CD8 T-cell memory in the H-2d haplotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Virally Infected Mouse Liver Endothelial Cells Trigger CD8+ T-Cell Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00430-012-0273-Y

Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion

21 January 2018

1 reference

12 December 2020

Preemptive CD8 T-cell immunotherapy of acute cytomegalovirus infection prevents lethal disease, limits the burden of latent viral genomes, and reduces the risk of virus recurrence

1 reference

12 December 2020

Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungs

1 reference

12 December 2020

Patchwork pattern of transcriptional reactivation in the lungs indicates sequential checkpoints in the transition from murine cytomegalovirus latency to recurrence

1 reference

12 December 2020

Functional roles of the human cytomegalovirus essential IE86 protein

1 reference

12 December 2020

Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance

1 reference

12 December 2020

Enhancer requirement for murine cytomegalovirus growth and genetic complementation by the human cytomegalovirus enhancer

1 reference

12 December 2020

Immediate-early genes of murine cytomegalovirus: location, transcripts, and translation products

1 reference

12 December 2020

Nonbacterial Pneumonia After Allogeneic Marrow Transplantation: A Review of Ten Years' Experience

1 reference

12 December 2020

Cellular localization of latent murine cytomegalovirus

1 reference

12 December 2020

Sequence and structural organization of murine cytomegalovirus immediate-early gene 1.

1 reference

12 December 2020

Pathogenesis of cytomegalovirus pneumonia in immunocompromised hosts.

1 reference

12 December 2020

Murine model of cytomegalovirus latency and reactivation.

1 reference

12 December 2020

Intra-abdominal bacterial infection reactivates latent pulmonary cytomegalovirus in immunocompetent mice

1 reference

12 December 2020

Control of murine cytomegalovirus in the lungs: relative but not absolute immunodominance of the immediate-early 1 nonapeptide during the antiviral cytolytic T-lymphocyte response in pulmonary infiltrates

1 reference

12 December 2020

Focal transcriptional activity of murine cytomegalovirus during latency in the lungs.

1 reference

12 December 2020

Lungs are a major organ site of cytomegalovirus latency and recurrence.

1 reference

12 December 2020

Latent murine cytomegalovirus DNA in splenic stromal cells of mice

1 reference

12 December 2020

Structure and expression of murine cytomegalovirus immediate-early gene 2.

1 reference

12 December 2020

Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3

1 reference

12 December 2020

Pathogenesis of murine cytomegalovirus infection: identification of infected cells in the spleen during acute and latent infections.

1 reference

12 December 2020

Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs

1 reference

12 December 2020

Initiation of cytomegalovirus infection at ND10.

1 reference

12 December 2020

10.1007/S00430-012-0273-Y

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

0 references

1 reference