Viral fitness: definitions, measurement, and current insights (Q38044156)

27 August 2017

Viral fitness: definitions, measurement, and current insights (English)

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27 August 2017

Andrew R Wargo

1

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PubMed ID

22986085

27 August 2017

Gael Kurath

series ordinal

2

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27 August 2017

15 September 2012

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Current opinion in virology

27 August 2017

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27 August 2017

2

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27 August 2017

5

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27 August 2017

538-545

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Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus

27 August 2017

1 reference

12 December 2020

Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1

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12 December 2020

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12 December 2020

Fitness epistasis and constraints on adaptation in a human immunodeficiency virus type 1 protein region

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12 December 2020

Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models.

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12 December 2020

Distribution of fitness effects caused by single-nucleotide substitutions in bacteriophage f1

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12 December 2020

In vivo fitness associated with high virulence in a vertebrate virus is a complex trait regulated by host entry, replication, and shedding

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12 December 2020

Human immunodeficiency virus type 1 fitness and tropism: concept, quantification, and clinical relevance.

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12 December 2020

Decreased infectivity of a neutralization-resistant equine infectious anemia virus variant can be overcome by efficient cell-to-cell spread

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12 December 2020

dN/dS-based methods detect positive selection linked to trade-offs between different fitness traits in the coat protein of potato virus Y.

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12 December 2020

A Cooperative Interaction between Nontranslated RNA Sequences and NS5A Protein Promotes In Vivo Fitness of a Chimeric Hepatitis C/GB Virus B

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12 December 2020

Initial fitness recovery of HIV-1 is associated with quasispecies heterogeneity and can occur without modifications in the consensus sequence

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12 December 2020

Dengue-1 virus clade replacement in Thailand associated with enhanced mosquito transmission

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12 December 2020

High replication fitness and transmission efficiency of HIV-1 subtype C from India: Implications for subtype C predominance

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12 December 2020

A mathematical framework for estimating pathogen transmission fitness and inoculum size using data from a competitive mixtures animal model

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12 December 2020

West Nile virus experimental evolution in vivo and the trade-off hypothesis

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12 December 2020

The fitness effects of synonymous mutations in DNA and RNA viruses

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12 December 2020

Mutation T74S in HIV-1 subtype B and C proteases resensitizes them to ritonavir and indinavir and confers fitness advantage.

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12 December 2020

High-throughput analysis of growth differences among phage strains.

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12 December 2020

Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus

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12 December 2020

Differences in accumulation and virulence determine the outcome of competition during Tobacco etch virus coinfection

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12 December 2020

Mechanisms of viral emergence

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12 December 2020

Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response

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12 December 2020

Oseltamivir-resistant pandemic H1N1/2009 influenza virus possesses lower transmissibility and fitness in ferrets

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12 December 2020

A viral dynamic model for treatment regimens with direct-acting antivirals for chronic hepatitis C infection

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12 December 2020

Effect of raltegravir resistance mutations in HIV-1 integrase on viral fitness

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12 December 2020

Divergent evolution in reverse transcriptase (RT) of HIV-1 group O and M lineages: impact on structure, fitness, and sensitivity to nonnucleoside RT inhibitors.

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12 December 2020

Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes

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12 December 2020

Viral adaptation to an antiviral protein enhances the fitness level to above that of the uninhibited wild type

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12 December 2020

In vivo fitness correlates with host-specific virulence of Infectious hematopoietic necrosis virus (IHNV) in sockeye salmon and rainbow trout

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12 December 2020

Emergence of the Asian 1 genotype of dengue virus serotype 2 in viet nam: in vivo fitness advantage and lineage replacement in South-East Asia

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12 December 2020

Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations

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12 December 2020

Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness

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12 December 2020

A point mutation in the polymerase of Potato virus Y confers virulence toward the Pvr4 resistance of pepper and a high competitiveness cost in susceptible cultivar

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12 December 2020

Gag determinants of fitness and drug susceptibility in protease inhibitor-resistant human immunodeficiency virus type 1.

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12 December 2020

Fitness and virulence of different strains of white spot syndrome virus

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12 December 2020

Rapid genetic diversification and high fitness penalties associated with pathogenicity evolution in a plant virus

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12 December 2020

Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models

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12 December 2020

Incongruent fitness landscapes, not tradeoffs, dominate the adaptation of vesicular stomatitis virus to novel host types

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12 December 2020

Carrying photosynthesis genes increases ecological fitness of cyanophage in silico

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12 December 2020

Mixed infections and the competitive fitness of faster-acting genetically modified viruses

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12 December 2020

The role of evolutionary intermediates in the host adaptation of canine parvovirus

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12 December 2020

Experimental evidence for competitive growth advantage of genotype VII over VI: implications for foot-and-mouth disease virus serotype A genotype turnover in nature

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12 December 2020

In vitro characterization of viral fitness of therapy-resistant hepatitis B variants

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12 December 2020

Abiotic heterogeneity drives parasite local adaptation in coevolving bacteria and phages

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12 December 2020

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

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12 December 2020

Viral and epidemiological determinants of the invasion dynamics of novel dengue genotypes

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12 December 2020

Growth of an RNA virus in single cells reveals a broad fitness distribution

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12 December 2020

Experimental evidence that source genetic variation drives pathogen emergence.

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12 December 2020

Exploring the fitness landscape of an RNA virus by using a universal barcode microarray

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12 December 2020

Cucumber mosaic virus satellite RNAs that induce similar symptoms in melon plants show large differences in fitness

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12 December 2020

Competitive fitness of oseltamivir-sensitive and -resistant highly pathogenic H5N1 influenza viruses in a ferret model

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12 December 2020

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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12 December 2020

Multiple genetic pathways to similar fitness limits during viral adaptation to a new host

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12 December 2020

Genomic evolution of vesicular stomatitis virus strains with differences in adaptability

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12 December 2020

CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemic

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12 December 2020

Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape

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12 December 2020

Point mutations in the West Nile virus (Flaviviridae; Flavivirus) RNA-dependent RNA polymerase alter viral fitness in a host-dependent manner in vitro and in vivo

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12 December 2020

Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types

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12 December 2020

Host alternation of chikungunya virus increases fitness while restricting population diversity and adaptability to novel selective pressures

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12 December 2020

Macaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus

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12 December 2020

RNA virus mutations and fitness for survival

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12 December 2020

Multidrug-resistant 2009 pandemic influenza A(H1N1) viruses maintain fitness and transmissibility in ferrets

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12 December 2020

10.1016/J.COVIRO.2012.07.007

Identifiers

DOI

1 reference

release_yfs6z6kkx5g2regcsilbklek4i

27 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/yfs6z6kkx5g2regcsilbklek4i

24 November 2022

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1 reference

PubMed ID

22986085