Promotion and inhibition of cardiac hypertrophy by A-kinase anchor proteins (Q38031570)

27 August 2017

title

Promotion and inhibition of cardiac hypertrophy by A-kinase anchor proteins (English)

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27 August 2017

Alexandra Blant

1

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27 August 2017

Michael P Czubryt

series ordinal

2

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27 August 2017

publication date

2 August 2012

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Canadian Journal of Physiology and Pharmacology

27 August 2017

published in

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27 August 2017

volume

90

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27 August 2017

issue

9

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27 August 2017

page(s)

1161-1170

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The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy

27 August 2017

cites work

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The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy

21 January 2018

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Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

21 January 2018

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The ubiquitin-like protein LC3 regulates the Rho-GEF activity of AKAP-Lbc

21 January 2018

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Isoform-specific differences between the type Ialpha and IIalpha cyclic AMP-dependent protein kinase anchoring domains revealed by solution NMR.

21 January 2018

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Network integration of the adrenergic system in cardiac hypertrophy

21 January 2018

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The mAKAP signalosome and cardiac myocyte hypertrophy.

21 January 2018

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A-kinase anchoring proteins and neuronal signaling mechanisms

21 January 2018

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AKAP-Lbc nucleates a protein kinase D activation scaffold

21 January 2018

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AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway

21 January 2018

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Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development

21 January 2018

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Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

21 January 2018

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Association of protein kinase A and protein phosphatase 2B with a common anchoring protein

21 January 2018

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AKAPs: from structure to function

21 January 2018

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Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy

21 January 2018

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Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

21 January 2018

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AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation

21 January 2018

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Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex

21 January 2018

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A-kinase anchoring proteins: scaffolding proteins in the heart.

21 January 2018

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AKAP79 and the evolution of the AKAP model

21 January 2018

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Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.

21 January 2018

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Mice lacking the Cβ subunit of PKA are resistant to angiotensin II-induced cardiac hypertrophy and dysfunction

21 January 2018

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The scaffold protein gravin (cAMP-dependent protein kinase-anchoring protein 250) binds the beta 2-adrenergic receptor via the receptor cytoplasmic Arg-329 to Leu-413 domain and provides a mobile scaffold during desensitization

21 January 2018

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Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes

21 January 2018

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Interference of antihypertrophic molecules and signaling pathways with the Ca2+-calcineurin-NFAT cascade in cardiac myocytes

21 January 2018

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Cardiac hypertrophy: the good, the bad, and the ugly

21 January 2018

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AKAP12 and AKAP5 form higher-order hetero-oligomers

21 January 2018

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SERCA pump optimizes Ca2+ release by a mechanism independent of store filling in smooth muscle cells

21 January 2018

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PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy

21 January 2018

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Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15

21 January 2018

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Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C-terminal domain.

21 January 2018

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Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy

21 January 2018

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An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytes

21 January 2018

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Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation

21 January 2018

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Calcineurin inhibition and cardiac hypertrophy: a matter of balance

21 January 2018

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The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin

21 January 2018

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Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylation

21 January 2018

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AKAP (A-kinase anchoring protein) domains: beads of structure-function on the necklace of G-protein signalling

21 January 2018

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Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

21 January 2018

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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

21 January 2018

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Signalosomes as Therapeutic Targets

21 January 2018

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The molecular basis for protein kinase A anchoring revealed by solution NMR

21 January 2018

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

21 January 2018

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Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

21 January 2018

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Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

21 January 2018

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Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

21 January 2018

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AKAP signalling complexes: focal points in space and time

21 January 2018

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mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha

21 January 2018

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Effects of angiotensin type I receptor blockade on the cardiac Raf/MEK/ERK cascade activated via adrenergic receptors

21 January 2018

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AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress

21 January 2018

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The potential use of AKAP18δ as a drug target in heart failure patients

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y2012-032

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27 August 2017

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