The evolving field of induced pluripotency: recent progress and future challenges (Q38024317)

27 August 2017

The evolving field of induced pluripotency: recent progress and future challenges (English)

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27 August 2017

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Gustavo Mostoslavsky

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author name string

Cesar A Sommer

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1

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27 August 2017

1 February 2013

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Journal of Cellular Physiology

27 August 2017

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27 August 2017

228

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27 August 2017

2

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27 August 2017

267-275

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Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency

27 August 2017

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Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

21 January 2018

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Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells

21 January 2018

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Generation of induced pluripotent stem cells in the absence of drug selection

21 January 2018

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Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

21 January 2018

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Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

21 January 2018

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Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

21 January 2018

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Modelling schizophrenia using human induced pluripotent stem cells

21 January 2018

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Reprogramming of murine and human somatic cells using a single polycistronic vector

21 January 2018

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Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells

21 January 2018

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

21 January 2018

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Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

21 January 2018

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Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells.

21 January 2018

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Molecular analyses of human induced pluripotent stem cells and embryonic stem cells

21 January 2018

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Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation.

21 January 2018

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Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes

21 January 2018

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Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

21 January 2018

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Induced pluripotent stem cells from a spinal muscular atrophy patient

21 January 2018

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Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

21 January 2018

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Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

21 January 2018

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Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector

21 January 2018

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Somatic coding mutations in human induced pluripotent stem cells

21 January 2018

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Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells

21 January 2018

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Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

21 January 2018

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Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

21 January 2018

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Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

21 January 2018

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Current technology for the derivation of pluripotent stem cell lines from human embryos

21 January 2018

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Nuclear reprogramming and pluripotency

21 January 2018

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Epigenetic reprogramming and induced pluripotency

21 January 2018

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Genetic engineering of human pluripotent cells using TALE nucleases

21 January 2018

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Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

21 January 2018

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

21 January 2018

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Copy number variation and selection during reprogramming to pluripotency

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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Modelling the long QT syndrome with induced pluripotent stem cells

21 January 2018

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A nonviral minicircle vector for deriving human iPS cells

21 January 2018

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Virus-free induction of pluripotency and subsequent excision of reprogramming factors

21 January 2018

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Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines

21 January 2018

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

21 January 2018

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Oct4-induced pluripotency in adult neural stem cells.

21 January 2018

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Epigenetic memory in induced pluripotent stem cells

21 January 2018

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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

21 January 2018

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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

21 January 2018

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

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Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

21 January 2018

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A cytoplasmic RNA vector derived from nontransmissible Sendai virus with efficient gene transfer and expression

21 January 2018

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A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

21 January 2018

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

21 January 2018

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Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts

21 January 2018

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Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells

21 January 2018

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Reprogramming of T cells from human peripheral blood

21 January 2018

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Generation of pluripotent stem cells from patients with type 1 diabetes

21 January 2018

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Guidelines and techniques for the generation of induced pluripotent stem cells

21 January 2018

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Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc

21 January 2018

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

21 January 2018

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A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

21 January 2018

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Transgenic mice with defined combinations of drug-inducible reprogramming factors

21 January 2018

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 January 2018

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Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

21 January 2018

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Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

21 January 2018

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Reprogramming of mouse and human cells to pluripotency using mature microRNAs.

21 January 2018

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Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

21 January 2018

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Patient-specific induced pluripotent stem-cell models for long-QT syndrome

21 January 2018

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A call to standardize teratoma assays used to define human pluripotent cell lines.

21 January 2018

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Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development

21 January 2018

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LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 January 2018

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Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming

21 January 2018

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Generation of germline-competent induced pluripotent stem cells

21 January 2018

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Generation of mouse induced pluripotent stem cells without viral vectors

21 January 2018

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Marked differences in differentiation propensity among human embryonic stem cell lines

21 January 2018

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Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

21 January 2018

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Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

21 January 2018

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Disease-specific induced pluripotent stem cells

21 January 2018

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Generation of human-induced pluripotent stem cells

21 January 2018

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Reprogramming of human somatic cells to pluripotency with defined factors

21 January 2018

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Progress in understanding reprogramming to the induced pluripotent state

21 January 2018

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

21 January 2018

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Differentiation of human embryonic stem cells after transplantation in immune-deficient mice

21 January 2018

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Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

21 January 2018

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Technical challenges in using human induced pluripotent stem cells to model disease

21 January 2018

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Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

21 January 2018

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Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells.

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds

21 January 2018

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Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

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Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.

21 January 2018

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Experimental approaches for the generation of induced pluripotent stem cells.

21 January 2018

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Induced pluripotent stem cell generation using a single lentiviral stem cell cassette

21 January 2018

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Induced pluripotency: history, mechanisms, and applications

21 January 2018

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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse

21 January 2018

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Induced pluripotent stem cells generated without viral integration

21 January 2018

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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

21 January 2018

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A reprogrammable mouse strain from gene-targeted embryonic stem cells

21 January 2018

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Reprogramming of human peripheral blood cells to induced pluripotent stem cells

21 January 2018

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Generation of functional human hepatic endoderm from human induced pluripotent stem cells

21 January 2018

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Human iPS cell-based therapy: considerations before clinical applications

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Diseases in a dish: modeling human genetic disorders using induced pluripotent cells

21 January 2018

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Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions

21 January 2018

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Chromosomal transposition of PiggyBac in mouse embryonic stem cells

21 January 2018

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

21 January 2018

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

21 January 2018

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Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

21 January 2018

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Viable offspring derived from fetal and adult mammalian cells

21 January 2018

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PiggyBac transposon-mediated gene transfer in human cells

21 January 2018

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No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells.

21 January 2018

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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

21 January 2018

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Gene therapy: therapeutic gene causing lymphoma

21 January 2018

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Generation of induced pluripotent stem cells from newborn marmoset skin fibroblasts

21 January 2018

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Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

21 January 2018

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Modeling familial Alzheimer's disease with induced pluripotent stem cells

21 January 2018

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Strategies and new developments in the generation of patient-specific pluripotent stem cells

21 January 2018

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Pluripotency and nuclear reprogramming

21 January 2018

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Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Human induced pluripotent stem cells free of vector and transgene sequences

21 January 2018

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Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

21 January 2018

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iPS cells produce viable mice through tetraploid complementation

21 January 2018

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Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells

21 January 2018

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Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

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Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

21 January 2018

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Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

21 January 2018

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Broader Implications of Defining Standards for the Pluripotency of iPSCs

21 January 2018

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Regeneration and orthotopic transplantation of a bioartificial lung

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24155

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27 August 2017

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PubMed ID

22767332