Cationic host defence peptides: multifaceted role in immune modulation and inflammation. (Q38022156)

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6 February 2020

title

Cationic host defence peptides: multifaceted role in immune modulation and inflammation (English)

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6 February 2020

1

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6 February 2020

Neeloffer Mookherjee

series ordinal

3

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6 February 2020

author name string

Leola N Y Chow

series ordinal

2

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6 February 2020

publication date

14 March 2012

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Journal of Innate Immunity

6 February 2020

published in

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6 February 2020

volume

4

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6 February 2020

page(s)

361-370

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6 February 2020

issue

4

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Antimicrobial peptides important in innate immunity

6 February 2020

cites work

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Host defence peptides-a bridge between the innate and adaptive immune responses

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Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

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The roles of antimicrobial peptides in innate host defense

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Innate immune peptide LL-37 displays distinct expression pattern from beta-defensins in inflamed gingival tissue.

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The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses

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Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

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Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

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LL-37 protects rats against lethal sepsis caused by gram-negative bacteria

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The antimicrobial peptide BMAP-28 reduces lethality in mouse models of staphylococcal sepsis

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Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats

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Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

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Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells

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Host defense peptide LL-37 selectively reduces proinflammatory macrophage responses.

21 January 2018

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Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide.

21 January 2018

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Interaction and cellular localization of the human host defense peptide LL-37 with lung epithelial cells.

21 January 2018

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LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

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Intracellular receptor for human host defense peptide LL-37 in monocytes

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Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide

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Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus

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Antimicrobial peptides and self-DNA in autoimmune skin inflammation

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Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases

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Safety of tumour necrosis factor and interleukin-1 blocking agents in rheumatic diseases

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Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs

21 January 2018

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Increased serum leucine, leucine-37 levels in psoriasis: positive and negative feedback loops of leucine, leucine-37 and pro- or anti-inflammatory cytokines

21 January 2018

1 reference

The cationic host defense peptide rCRAMP promotes gastric ulcer healing in rats

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Neutrophil secretion products pave the way for inflammatory monocytes

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1 reference

Monocyte-chemotactic activity of defensins from human neutrophils

21 January 2018

1 reference

Fusobacterium nucleatum and human beta-defensins modulate the release of antimicrobial chemokine CCL20/macrophage inflammatory protein 3α

21 January 2018

1 reference

Involvement of P2X(7) purinergic receptor and MEK1/2 in interleukin-8 up-regulation by LL-37 in human gingival fibroblasts.

21 January 2018

1 reference

Immunomodulatory properties of defensins and cathelicidins

21 January 2018

1 reference

Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells

21 January 2018

1 reference

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

21 January 2018

1 reference

Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages

21 January 2018

1 reference

Neutrophil-derived cathelicidin protects from neointimal hyperplasia

21 January 2018

1 reference

Host defense peptides in wound healing.

21 January 2018

1 reference

Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells

21 January 2018

1 reference

Protein chimeras containing the Mycoplasma bovis GAPDH protein and bovine host-defence peptides retain the properties of the individual components

21 January 2018

1 reference

CpG oligodeoxynucleotide synergizes innate defense regulator peptide for enhancing the systemic and mucosal immune responses to pseudorabies attenuated virus vaccine in piglets in vivo

21 January 2018

1 reference

Effects of the antimicrobial peptide LL-37 and hyperthermic preconditioning in septic rats.

21 January 2018

1 reference

Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis

21 January 2018

1 reference

Maternal plasma level of antimicrobial peptide LL37 is a major determinant factor of neonatal plasma LL37 level

21 January 2018

1 reference

Expression and activity of beta-defensins and LL-37 in the developing human lung.

21 January 2018

1 reference

Oral antimicrobial peptides and biological control of caries

21 January 2018

1 reference

Raised plasma concentrations of alpha-defensins in patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity

21 January 2018

1 reference

Defensins and other antimicrobial peptides in inflammatory bowel disease

21 January 2018

1 reference

Antimicrobial peptides are expressed and produced in healthy and inflamed human synovial membranes

21 January 2018

1 reference

Allergic airway inflammation inhibits pulmonary antibacterial host defense

21 January 2018

1 reference

Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease

21 January 2018

1 reference

Increased Bronchoalveolar Lavage Human ??-Defensin Type 2 in Bronchiolitis Obliterans Syndrome after Lung Transplantation

21 January 2018

1 reference

Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo

21 January 2018

1 reference

Endogenous antimicrobial peptides and skin infections in atopic dermatitis

21 January 2018

1 reference

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

21 January 2018

1 reference

Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A

21 January 2018

1 reference

Sequence Requirements and an Optimization Strategy for Short Antimicrobial Peptides

21 January 2018

1 reference

Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells

21 January 2018

1 reference

12 December 2020

Defensins enable macrophages to inhibit the intracellular proliferation of Listeria monocytogenes

1 reference

12 December 2020

PR39, a peptide regulator of angiogenesis

1 reference

12 December 2020

Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways

1 reference

12 December 2020

Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome

1 reference

12 December 2020

The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization

1 reference

12 December 2020

Antimicrobial peptide LL-37 internalized by immature human dendritic cells alters their phenotype

1 reference

12 December 2020

The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes

1 reference

12 December 2020

An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.

1 reference

12 December 2020

Evaluation of the effect of human beta-defensins on neutrophil apoptosis

1 reference

12 December 2020

Strategies for the discovery and advancement of novel cationic antimicrobial peptides.

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12 December 2020

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

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12 December 2020

Human cathelicidin LL-37 is a chemoattractant for eosinophils and neutrophils that acts via formyl-peptide receptors

1 reference

12 December 2020

LL-37 expression in the skin in systemic lupus erythematosus

1 reference

12 December 2020

Chemoattractant properties of PR-39, a neutrophil antibacterial peptide.

1 reference

12 December 2020

An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7.

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12 December 2020

A cathelicidin-2-derived peptide effectively impairs Staphylococcus epidermidis biofilms

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12 December 2020

Identifiers

DOI

10.1159/000336630

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6 February 2020

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6 February 2020

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