Structure, regulation and cellular functions of Rab geranylgeranyl transferase and its cellular partner Rab Escort Protein (Q38018351)

27 August 2017

Structure, regulation and cellular functions of Rab geranylgeranyl transferase and its cellular partner Rab Escort Protein (English)

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27 August 2017

2

Ewa Swiezewska

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27 August 2017

Malgorzata Gutkowska

1

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27 August 2017

14 June 2012

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Molecular Membrane Biology

27 August 2017

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27 August 2017

29

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27 August 2017

7

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27 August 2017

243-256

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Organization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease

27 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Molecular evolution of the Rab-escort-protein/guanine-nucleotide-dissociation-inhibitor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Amino- and carboxy-terminal domains of the yeast Rab escort protein are both required for binding of Ypt small G proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The C2 domain of PKCdelta is a phosphotyrosine binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

New type of mutations in three spanish families with choroideremia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Arabidopsis RAB geranylgeranyl transferase beta-subunit mutant is constitutively photomorphogenic, and has shoot growth and gravitropic defects.

21 January 2018

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https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Role of Rab GTPases in membrane traffic and cell physiology

21 January 2018

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https://api.crossref.org/works/10.3109%2F09687688.2012.693211

A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

21 January 2018

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https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The leucine-rich repeat as a protein recognition motif

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Regulation of β2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Geranylgeranyl transferase type II inhibition prevents myeloma bone disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

5'-UTR structural organization, transcript expression, and mutational analysis of the human Rab geranylgeranyl transferase alpha-subunit (RABGGTA) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Cell transplantation as a treatment for retinal disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Choroideremia gene testing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The yeast Rab escort protein binds intracellular membranes in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Ypt protein prenylation depends on the interplay among levels of Rab escort protein and geranylgeranyl diphosphate in yeast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Rab GTPases implicated in inherited and acquired disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The C2 domain calcium-binding motif: structural and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Understanding and exploiting protein prenyltransferases

21 January 2018

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https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Analysis of the eukaryotic prenylome by isoprenoid affinity tagging

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The yeast protein Mrs6p, a homologue of the rabGDI and human choroideraemia proteins, affects cytoplasmic and mitochondrial functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Multiple domain insertions and losses in the evolution of the Rab prenylation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Biochemical and molecular mechanisms of action of bisphosphonates.

21 January 2018

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https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Deficient geranylgeranylation of Ram/Rab27 in choroideremia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

The functional effect of pathogenic mutations in Rab escort protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Choroideremia gene product affects trophoblast development and vascularization in mouse extra-embryonic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Griscelli syndrome: a model system to study vesicular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

MRS6--yeast homologue of the choroideraemia gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Yeast geranylgeranyltransferase type-II: steady state kinetic studies of the recombinant enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Structure of the disordered C terminus of Rab7 GTPase induced by binding to the Rab geranylgeranyl transferase catalytic complex reveals the mechanism of Rab prenylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09687688.2012.693211

10.3109/09687688.2012.693211

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

22694141