Application of optical biosensors in small-molecule screening activities (Q38016148)

27 August 2017

2 references

19 September 2019

4 November 2020

Application of optical biosensors in small-molecule screening activities (English)

1 reference

biomedical investigative technique

27 August 2017

1 reference

19 September 2019

1 reference

4 November 2020

Stefan Geschwindner

1

1 reference

27 August 2017

Johan F Carlsson

series ordinal

2

1 reference

27 August 2017

Wolfgang Knecht

series ordinal

3

1 reference

27 August 2017

language of work or name

English

0 references

publication date

28 March 2012

3 references

27 August 2017

19 September 2019

4 November 2020

3 references

27 August 2017

19 September 2019

4 November 2020

12

1 reference

27 August 2017

4

1 reference

27 August 2017

4311-4323

1 reference

Creative Commons Attribution

27 August 2017

2 references

19 September 2019

4 November 2020

0 references

From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Fragment screening of stabilized G-protein-coupled receptors using biophysical methods

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Fragment screening to predict druggability (ligandability) and lead discovery success.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Biacore analysis with stabilized G-protein-coupled receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Fragment library screening and lead characterization using SPR biosensors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

NMR methods in fragment screening: theory and a comparison with other biophysical techniques

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Label-free primary screening and affinity ranking of fragment libraries using parallel analysis of protein panels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Discovery of a novel warhead against beta-secretase through fragment-based lead generation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

A new strategy for improved secondary screening and lead optimization using high-resolution SPR characterization of compound-target interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

A 100K well screen for a muscarinic receptor using the Epic label-free system--a reflection on the benefits of the label-free approach to screening seven-transmembrane receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Resonant waveguide grating biosensor for living cell sensing.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Kinetic efficiency: the missing metric for enhancing compound quality?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

HTS reporter displacement assay for fragment screening and fragment evolution toward leads with optimized binding kinetics, binding selectivity, and thermodynamic signature

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Affinity-based, biophysical methods to detect and analyze ligand binding to recombinant proteins: matching high information content with high throughput.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Label-free assays on the BIND system.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Equilibrium and kinetic analyses of the interactions between vitamin B(12) binding proteins and cobalamins by surface plasmon resonance

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Study of substrate-enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Real-time competitive kinetic analysis of interactions between low-molecular-weight ligands in solution and surface-immobilized receptors

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Adding calorimetric data to decision making in lead discovery: a hot tip

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Identification of MMP-12 Inhibitors by Using Biosensor-Based Screening of a Fragment Library

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355412

Immobilization chemistries suitable for use in the BIAcore surface plasmon resonance detector

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22666031

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Surface plasmon resonance based assay for the detection and characterization of promiscuous inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22666031

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of binding kinetics in therapeutically useful drug action

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22666031

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/S120404311

1 reference

journals/sensors/GeschwindnerCK12

27 August 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

27 August 2017

PubMed publication ID

22666031

1 reference