Lynch syndrome diagnostics: decision-making process for germ-line testing (Q38000941)

26 August 2017

Lynch syndrome diagnostics: decision-making process for germ-line testing (English)

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26 August 2017

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E Lastra

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26 August 2017

M García-González

2

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26 August 2017

B Llorente

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26 August 2017

C Bernuy

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26 August 2017

M J Barrio

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26 August 2017

L Pérez-Cabornero

6

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26 August 2017

M Durán

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26 August 2017

C García-Girón

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26 August 2017

1 April 2012

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Clinical and Translational Oncology

26 August 2017

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26 August 2017

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26 August 2017

254-262

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https://scigraph.springernature.com/pub.10.1007/s12094-012-0793-3

26 August 2017

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cites work

Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).

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Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X

21 January 2018

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Who should be sent for genetic testing in hereditary colorectal cancer syndromes?

21 January 2018

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Feasibility of screening for Lynch syndrome among patients with colorectal cancer

21 January 2018

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Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.

21 January 2018

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Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients

21 January 2018

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Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Prediction of germline mutations and cancer risk in the Lynch syndrome

21 January 2018

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Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part I. The utility of immunohistochemistry

21 January 2018

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Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer

21 January 2018

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Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database

21 January 2018

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Oxidative stress inactivates the human DNA mismatch repair system.

21 January 2018

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Regulation of DNA repair in hypoxic cancer cells

21 January 2018

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The utility of immunohistochemical detection of DNA mismatch repair gene proteins.

21 January 2018

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Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome. Part II. The utility of microsatellite instability testing

21 January 2018

1 reference

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Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant

21 January 2018

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Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history

21 January 2018

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Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance

21 January 2018

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hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

21 January 2018

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Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair

21 January 2018

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21 January 2018

12 December 2020

Development of a fluorescent multiplex assay for detection of MSI-High tumors

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Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR.

21 January 2018

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Recent insights into the pathogenesis of colorectal cancer.

21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum

21 January 2018

1 reference

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BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing

21 January 2018

1 reference

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

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Epigenetic changes in colorectal cancer.

21 January 2018

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Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis

21 January 2018

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Germline epimutation in humans

21 January 2018

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DNA methylation, epimutations and cancer predisposition

21 January 2018

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Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.

21 January 2018

1 reference

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Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

21 January 2018

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Erasure of MLH1 methylation in spermatozoa—implications for epigenetic inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Somatic hypermethylation of MSH2 is a frequent event in Lynch Syndrome colorectal cancers

21 January 2018

1 reference

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Recurrence and variability of germline EPCAM deletions in Lynch syndrome.

21 January 2018

1 reference

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Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

21 January 2018

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The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside

21 January 2018

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Microsatellites in the eukaryotic DNA mismatch repair genes as modulators of evolutionary mutation rate

21 January 2018

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Prediction of MLH1 and MSH2 Mutations in Lynch Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

RAF/RAS oncogenes and mismatch-repair status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Frequency of constitutional MSH6 mutations in a consecutive series of families with clinical suspicion of HNPCC

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-012-0793-3

Microsatellite Instability and hMLH1 and hMSH2 expression analysis in familial and sporadic colorectal cancer

21 January 2018

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12 December 2020

Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families

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12 December 2020

Heritable germline epimutation is not the same as transgenerational epigenetic inheritance

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12 December 2020

Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining

1 reference

12 December 2020

Prophylactic Surgery to Reduce the Risk of Gynecologic Cancers in the Lynch Syndrome

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12 December 2020

Prospective Determination of Prevalence of Lynch Syndrome in Young Women With Endometrial Cancer

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12 December 2020

Analysis of EPCAM protein expression in diagnostics of Lynch syndrome

1 reference

12 December 2020

Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC

1 reference

12 December 2020

Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma

1 reference

12 December 2020

10.1007/S12094-012-0793-3

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DOI

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26 August 2017

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