The mystery of C. elegans aging: an emerging role for fat. Distant parallels between C. elegans aging and metabolic syndrome? (Q37988793)

26 August 2017

The mystery of C. elegans aging: an emerging role for fat. Distant parallels between C. elegans aging and metabolic syndrome? (English)

1 reference

26 August 2017

Caenorhabditis elegans

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1 reference

David Gems

2

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author name string

Daniel Ackerman

series ordinal

1

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PubMed ID

22371137

26 August 2017

language of work or name

English

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publication date

27 February 2012

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26 August 2017

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26 August 2017

34

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26 August 2017

466-471

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26 August 2017

6

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26 August 2017

The genetics of ageing

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Is the oxidative stress theory of aging dead?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Signals from the reproductive system regulate the lifespan of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Regulation of life-span by germ-line stem cells in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Fat metabolism links germline stem cells and longevity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Autophagy regulates ageing in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Autophagy is required for dietary restriction-mediated life span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Autophagy regulates lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

C. elegans major fats are stored in vesicles distinct from lysosome-related organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Lipotoxicity: when tissues overeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Role of visceral adipose tissue in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Cellular mechanisms of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

A novel mouse model of lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Distribution and transport of cholesterol in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Shuttling between species for pathways of lifespan regulation: a central role for the vitellogenin gene family?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Redox regulation of germline and vulval development in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Loss of intestinal nuclei and intestinal integrity in aging C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Regulation of Caenorhabditis elegans vitellogenesis by DAF-2/IIS through separable transcriptional and posttranscriptional mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Transcriptional profile of aging in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Genetic mouse models of extended lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100189

21 January 2018

Identifiers

DOI

10.1002/BIES.201100189

1 reference

26 August 2017

1 reference

PubMed ID

22371137