Neuroprotective mechanisms of hypothermia in brain ischaemia (Q37986997)

26 August 2017

Neuroprotective mechanisms of hypothermia in brain ischaemia (English)

1 reference

26 August 2017

1 reference

Midori A Yenari

1

1 reference

PubMed ID

22353781

26 August 2017

Hyung Soo Han

series ordinal

2

1 reference

PubMed ID

22353781

26 August 2017

language of work or name

English

0 references

publication date

22 February 2012

1 reference

Nature Reviews Neuroscience

26 August 2017

1 reference

26 August 2017

13

1 reference

26 August 2017

4

1 reference

26 August 2017

267-278

1 reference

https://scigraph.springernature.com/pub.10.1038/nrn3174

26 August 2017

0 references

cites work

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury.

1 reference

Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia

31 March 2020

1 reference

Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest

31 March 2020

1 reference

Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial.

31 March 2020

1 reference

Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.

31 March 2020

1 reference

Suspended animation can allow survival without brain damage after traumatic exsanguination cardiac arrest of 60 minutes in dogs

31 March 2020

1 reference

The evidence for hypothermia as a neuroprotectant in traumatic brain injury

31 March 2020

1 reference

Protection in animal models of brain and spinal cord injury with mild to moderate hypothermia

31 March 2020

1 reference

An automated system for regulating brain temperature in awake and freely moving rodents.

31 March 2020

1 reference

Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis

31 March 2020

1 reference

Therapeutic hypothermia for acute ischemic stroke: what do laboratory studies teach us?

31 March 2020

1 reference

Metabolic downregulation: a key to successful neuroprotection?

31 March 2020

1 reference

Indefatigable CA1 sector neuroprotection with mild hypothermia induced 6 hours after severe forebrain ischemia in rats.

31 March 2020

1 reference

Delayed induction and long-term effects of mild hypothermia in a focal model of transient cerebral ischemia: neurological outcome and infarct size

31 March 2020

1 reference

Therapeutic applications of hypothermia in cerebral ischaemia

31 March 2020

1 reference

Effects of hypothermia on energy metabolism in Mammalian central nervous system

31 March 2020

1 reference

General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage

31 March 2020

1 reference

The changing landscape of ischaemic brain injury mechanisms.

31 March 2020

1 reference

Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia

31 March 2020

1 reference

Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats.

31 March 2020

1 reference

Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia

31 March 2020

1 reference

Hypothermia enhances heat-shock protein 70 production in ischemic brains.

31 March 2020

1 reference

Characterization of hypothermia-induced cellular stress response in mouse tissues

31 March 2020

1 reference

Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection

31 March 2020

1 reference

The effect of hypothermia on induction of heat shock protein (HSP)-72 in ischemic brain

31 March 2020

1 reference

Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade.

31 March 2020

1 reference

The MicroRNAs and Stroke: No Need to be Coded to be Counted

31 March 2020

1 reference

Therapeutic hypothermia alters microRNA responses to traumatic brain injury in rats

31 March 2020

1 reference

Mitochondria and apoptosis

31 March 2020

1 reference

Death receptors: signaling and modulation

31 March 2020

1 reference

Therapeutic hypothermia: neuroprotective mechanisms

31 March 2020

1 reference

Protein kinase C delta mediates cerebral reperfusion injury in vivo.

31 March 2020

1 reference

Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation

31 March 2020

1 reference

The protective effect of early hypothermia on PTEN phosphorylation correlates with free radical inhibition in rat stroke

31 March 2020

1 reference

Epsilon PKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model.

31 March 2020

1 reference

Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

31 March 2020

1 reference

FasL shedding is reduced by hypothermia in experimental stroke

31 March 2020

1 reference

Multiple roles for MMPs and TIMPs in cerebral ischemia

31 March 2020

1 reference

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

31 March 2020

1 reference

Mild to moderate hypothermia prevents microvascular basal lamina antigen loss in experimental focal cerebral ischemia.

31 March 2020

1 reference

Reduction in levels of matrix metalloproteinases and increased expression of tissue inhibitor of metalloproteinase-2 in response to mild hypothermia therapy in experimental stroke.

31 March 2020

1 reference

Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats.

31 March 2020

1 reference

Topographically graded postischemic presence of metalloproteinases is inhibited by hypothermia.

31 March 2020

1 reference

Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke

31 March 2020

1 reference

Molecular characterization of mitochondrial apoptosis-inducing factor

31 March 2020

1 reference

Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion

31 March 2020

1 reference

PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

31 March 2020

1 reference

Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrest

31 March 2020

1 reference

Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation

31 March 2020

1 reference

Regional changes in glial cell line-derived neurotrophic factor after cardiac arrest and hypothermia in rats

31 March 2020

1 reference

The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat.

31 March 2020

1 reference

Hypothermia differentially increases extracellular signal-regulated kinase and stress-activated protein kinase/c-Jun terminal kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest

31 March 2020

1 reference

Hypothermia and ERK activation after cardiac arrest

31 March 2020

1 reference

Hypothermia enhances bcl-2 expression and protects against oxidative stress-induced cell death in Chinese hamster ovary cells

31 March 2020

1 reference

Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia

31 March 2020

1 reference

Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats.

31 March 2020

1 reference

The inflammatory response in stroke

31 March 2020

1 reference

The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia

31 March 2020

1 reference

Whole Body Hypothermia and Oxidative Stress in Babies With Hypoxic-Ischemic Brain Injury

31 March 2020

1 reference

Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation.

31 March 2020

1 reference

Mild hypothermia inhibits inflammation after experimental stroke and brain inflammation.

31 March 2020

1 reference

Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation

31 March 2020

1 reference

Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia

31 March 2020

1 reference

IL-10 production is reduced by hypothermia but augmented by hyperthermia in rat microglia

31 March 2020

1 reference

The effect of therapeutic hypothermia on the expression of inflammatory response genes following moderate traumatic brain injury in the rat

31 March 2020

1 reference

Influence of hypothermia on post-ischemic inflammation: role of nuclear factor kappa B (NFkappaB)

31 March 2020

1 reference

Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke.

31 March 2020

1 reference

Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia.

31 March 2020

1 reference

Roles of nuclear factor kappaB in neuronal survival and plasticity

31 March 2020

1 reference

Hypothermia suppresses inflammation via ERK signaling pathway in stimulated microglial cells.

31 March 2020

1 reference

The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia.

31 March 2020

1 reference

Effect of delayed mild brain hypothermia on edema formation after intracerebral hemorrhage in rats.

31 March 2020

1 reference

The influence of hypothermia on outcome after intracerebral hemorrhage in rats.

31 March 2020

1 reference

Combinational therapy using hypothermia and the immunophilin ligand FK506 to target altered pial arteriolar reactivity, axonal damage, and blood-brain barrier dysfunction after traumatic brain injury in rat.

31 March 2020

1 reference

A two-hour window for hypothermic modulation of early events that impact delayed opening of the rat blood-brain barrier after ischemia

31 March 2020

1 reference

Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: effects on BBB breakdown and MMP expression in the acute and subacute phase

31 March 2020

1 reference

Post-ischemic hypothermia attenuates loss of the vascular basement membrane proteins, agrin and SPARC, and the blood-brain barrier disruption after global cerebral ischemia

31 March 2020

1 reference

The effect of moderate hypothermia in acute ischemic stroke on pericyte migration: an ultrastructural study

31 March 2020

1 reference

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

31 March 2020

1 reference

Cerebral cortical aquaporin-4 expression in brain edema following cardiac arrest in rats

31 March 2020

1 reference

Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs.

31 March 2020

1 reference

Treatment of intracerebral hemorrhage in rats with 12 h, 3 days and 6 days of selective brain hypothermia.

31 March 2020

1 reference

Hypothermia reduces perihemorrhagic edema after intracerebral hemorrhage.

31 March 2020

1 reference

Coagulopathy by hypothermia and acidosis: mechanisms of thrombin generation and fibrinogen availability

31 March 2020

1 reference

The effects of hypothermia on fibrinogen metabolism and coagulation function in swine

31 March 2020

1 reference

Forebrain neurogenesis after focal Ischemic and traumatic brain injury

31 March 2020

1 reference

Angiogenesis, neurogenesis and neuroplasticity in ischemic stroke

31 March 2020

1 reference

Neurogenesis in the aged and neurodegenerative brain

31 March 2020

1 reference

Decline in adult neurogenesis during aging follows a topographic pattern in the mouse hippocampus.

31 March 2020

1 reference

A decrease of cell proliferation by hypothermia in the hippocampus of the neonatal rat.

31 March 2020

1 reference

Post-ischemic hypothermia promotes generation of neural cells and reduces apoptosis by Bcl-2 in the striatum of neonatal rat brain.

31 March 2020

1 reference

Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein

31 March 2020

1 reference

Therapeutic hypothermia influences cell genesis and survival in the rat hippocampus following global ischemia.

31 March 2020

1 reference

Mild hypothermia has no long-term impact on postischemic neurogenesis in rats.

31 March 2020

1 reference

Oligodendrocyte vulnerability following traumatic brain injury in rats

31 March 2020

1 reference

OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA.

31 March 2020

1 reference

Hypothermia-induced increase of oligodendrocyte precursor cells: Possible involvement of plasmalemmal voltage-dependent anion channel 1

31 March 2020

1 reference

The effect of cerebral hypothermia on white and grey matter injury induced by severe hypoxia in preterm fetal sheep

31 March 2020

1 reference

Stem cells in stroke repair: current success and future prospects

31 March 2020

1 reference

Focal cerebral ischemia induces a multilineage cytogenic response from adult subventricular zone that is predominantly gliogenic

31 March 2020

1 reference

The unusual response of serotonergic neurons after CNS Injury: lack of axonal dieback and enhanced sprouting within the inhibitory environment of the glial scar

31 March 2020

1 reference

Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning

31 March 2020

1 reference

Effect of mild hypothermia on angiogenesis in rats with focal cerebral ischemia

31 March 2020

1 reference

Body cooling ameliorating spinal cord injury may be neurogenesis-, anti-inflammation- and angiogenesis-associated in rats

31 March 2020

1 reference

Brain cooling-stimulated angiogenesis and neurogenesis attenuated traumatic brain injury in rats

31 March 2020

1 reference

A large screening of angiogenesis biomarkers and their association with neurological outcome after ischemic stroke

31 March 2020

1 reference

Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis

31 March 2020

1 reference

Hypothermia-induced neurite outgrowth is mediated by tumor necrosis factor-alpha

31 March 2020

1 reference

S100B modulates IL-6 release and cytotoxicity from hypothermic brain cells and inhibits hypothermia-induced axonal outgrowth.

31 March 2020

1 reference

Effect of therapeutic mild hypothermia on the genomics of the hippocampus after moderate traumatic brain injury in rats

31 March 2020

1 reference

Complications and treatment of mild hypothermia

31 March 2020

1 reference

Hibernation in ground squirrels induces state and species-specific tolerance to hypoxia and aglycemia: an in vitro study in hippocampal slices.

31 March 2020

1 reference

Protein kinase C epsilon activation delays neuronal depolarization during cardiac arrest in the euthermic arctic ground squirrel

31 March 2020

1 reference

Hypoxia tolerance in mammalian heterotherms.

31 March 2020

1 reference

Hibernation in black bears: independence of metabolic suppression from body temperature.

31 March 2020

1 reference

Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs

31 March 2020

1 reference

Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain

31 March 2020

1 reference

Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase

31 March 2020

1 reference

Hypothermia causes a reversible, p53-mediated cell cycle arrest in cultured fibroblasts

31 March 2020

1 reference

12 December 2020

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons.

1 reference

12 December 2020

[Effect of local mild hypothermia on expression of aquaporin-4 following intracerebral hemorrhage in rats].

1 reference

12 December 2020

Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

1 reference

12 December 2020

Therapeutic modulation of brain temperature: relevance to ischemic brain injury

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRN3174

1 reference

26 August 2017

1 reference

PubMed ID

22353781