Matrix metalloproteinase inhibition therapy for vascular diseases (Q37983293)

26 August 2017

Matrix metalloproteinase inhibition therapy for vascular diseases (English)

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26 August 2017

Andrew C Newby

1

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26 August 2017

1 February 2012

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26 August 2017

Vascular Pharmacology

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26 August 2017

56

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26 August 2017

232-244

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26 August 2017

5-6

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Collagen degradation in the abdominal aneurysm: a conspiracy of matrix metalloproteinase and cysteine collagenases

26 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Zinc-binding groups modulate selective inhibition of MMPs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Relationship between type IV collagen degradation, metalloproteinase activity and smooth muscle cell migration and proliferation in cultured human saphenous vein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

CD44 is the principal cell surface receptor for hyaluronate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Prospective, Randomized, Double-Blind Trial Investigating the Effect of Doxycycline on Matrix Metalloproteinase Expression Within Atherosclerotic Carotid Plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Localized administration of doxycycline suppresses aortic dilatation in an experimental mouse model of abdominal aortic aneurysm.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Prolonged administration of doxycycline in patients with small asymptomatic abdominal aortic aneurysms: report of a prospective (Phase II) multicenter study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline modulates smooth muscle cell growth, migration, and matrix remodeling after arterial injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Early differential MMP-2 and -9 dynamics during flow-induced arterial and vein graft adaptations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The matrix metalloproteinase inhibitor BB-94 limits expansion of experimental abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Inhibition of transcription factor NF-kappaB reduces matrix metalloproteinase-1, -3 and -9 production by vascular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline inhibits elastin degradation and reduces metalloproteinase activity in a model of aneurysmal disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The role of the matrix metalloproteinases during in vitro vessel formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Coronary risk factors and plaque morphology in men with coronary disease who died suddenly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Effect of risk factors on the mechanism of acute thrombosis and sudden coronary death in women.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Stromelysin-1 (matrix metalloproteinase-3) and tissue inhibitor of metalloproteinase-3 are overexpressed in the wall of abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Role of nuclear factor-kappa B activation in metalloproteinase-1, -3, and -9 secretion by human macrophages in vitro and rabbit foam cells produced in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A BAC-based STS-content map spanning a 35-Mb region of human chromosome 1p35-p36

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Extracellular matrix metalloproteinase inducer (EMMPRIN) is present in smooth muscle cells of human aneurysmal aorta and is induced by angiotensin II in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Adenovirus-mediated gene transfer of the human tissue inhibitor of metalloproteinase-2 blocks vascular smooth muscle cell invasiveness in vitro and modulates neointimal development in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Metalloproteinase inhibition and the response to angioplasty and stenting in atherosclerotic primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

RECK--a newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The regulation of matrix metalloproteinases and their inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Targeting matrix metalloproteinases in inflammatory conditions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Pharmacologic suppression of experimental abdominal aortic aneurysms: acomparison of doxycycline and four chemically modified tetracyclines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

New Strategies for the Next Generation of Matrix-Metalloproteinase Inhibitors: Selectively Targeting Membrane-Anchored MMPs with Therapeutic Antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases in the aneurysm wall of patients treated with low-dose doxycycline

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline inhibition of abdominal aortic aneurysm growth: a systematic review of the literature

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression of tissue inhibitor of matrix metalloproteinases 1 by use of an adenoviral vector inhibits smooth muscle cell migration and reduces neointimal hyperplasia in the rat model of vascular balloon injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Neutrophil elastase in human atherosclerotic plaques: production by macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase inhibitors: a critical appraisal of design principles and proposed therapeutic utility.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Thrombin receptor-mediated increase of two matrix metalloproteinases, MMP-1 and MMP-3, in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Key role of the NO-pathway and matrix metalloprotease-9 in high blood flow-induced remodeling of rat resistance arteries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Structural basis for the highly selective inhibition of MMP-13.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Intravital microscopy on atherosclerosis in apolipoprotein e-deficient mice establishes microvessels as major entry pathways for leukocytes to advanced lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Overexpression of tissue inhibitor of matrix metalloproteinase-1 inhibits vascular smooth muscle cell functions in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline alters vascular smooth muscle cell adhesion, migration, and reorganization of fibrillar collagen matrices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Gene transfer of tissue inhibitor of metalloproteinase-2 inhibits metalloproteinase activity and neointima formation in human saphenous veins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Inhibition of late vein graft neointima formation in human and porcine models by adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Sustained reduction of vein graft neointima formation by ex vivo TIMP-3 gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Remodeling of carotid artery is associated with increased expression of matrix metalloproteinases in mouse blood flow cessation model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Current status of medical management for abdominal aortic aneurysm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Pyrimidine-2,4,6-Triones: a new effective and selective class of matrix metalloproteinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Egr-1 mediates extracellular matrix-driven transcription of membrane type 1 matrix metalloproteinase in endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A randomized, placebo-controlled trial of doxycycline after endoluminal aneurysm repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Transcriptional up-regulation of endothelial cell matrix metalloproteinase-2 in response to extracellular cues involves GATA-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Vascular expression of matrix metalloproteinase-13 (collagenase-3) in basal cell carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression of Neutrophil Gelatinase–Associated Lipocalin in Atherosclerosis and Myocardial Infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Regulation of matrilysin expression in endothelium by fibroblast growth factor-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Imaging of Abdominal Aortic Aneurysm: the present and the future.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Oxidized LDL differentially regulates MMP-1 and TIMP-1 expression in vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A Nonantibiotic Chemically Modified Tetracycline (CMT-3) Inhibits Intimal Thickening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MT1-MMP: a key regulator of cell migration in tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix Metalloproteinase-2 and −9 Differentially Regulate Smooth Muscle Cell Migration and Cell-Mediated Collagen Organization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Suppression of Atherosclerotic Plaque Progression and Instability by Tissue Inhibitor of Metalloproteinase-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Effect of broad-spectrum matrix metalloproteinase inhibition on atherosclerotic plaque stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix Metalloproteinase (MMP)-3 Activates MMP-9 Mediated Vascular Smooth Muscle Cell Migration and Neointima Formation in Mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Role of matrix metalloproteinases in the inflammatory process of respiratory diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A role of matrix metalloproteinase-8 in atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Increased medial degradation with pseudo-aneurysm formation in apolipoprotein E-knockout mice deficient in tissue inhibitor of metalloproteinases-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

TIMP3 mutation in Sorsby's fundus dystrophy: molecular insights

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Lessons on the pathogenesis of aneurysm from heritable conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Nitric oxide induces the progression of abdominal aortic aneurysms through the matrix metalloproteinase inducer EMMPRIN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MMP-12 has a role in abdominal aortic aneurysms in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism: implications for tubule formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases as modulators of inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression of collagenase-3 (MMP-13) in human abdominal aortic aneurysms and vascular smooth muscle cells in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: a randomized, double-blind, placebo-controlled pilot study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Structure and function of matrix metalloproteinases and TIMPs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Expression of matrilysin in vascular endothelial cells adjacent to matrilysin-producing tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Selective MMP-inhibition with Ro 28-2653 in acute experimental stroke--a magnetic resonance imaging efficacy study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Metalloproteinase expression in monocytes and macrophages and its relationship to atherosclerotic plaque instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The expression and localization of membrane type-1 matrix metalloproteinase in human abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Pathophysiology and epidemiology of abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases and the regulation of tissue remodelling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases as modulators of inflammation and innate immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Overexpression of a secretory form of FGF-1 promotes MMP-1-mediated endothelial cell migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

cAMP involvement in the expression of MMP-2 and MT-MMP1 metalloproteinases in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Activity of matrix metalloproteinase-2 and -9 in abdominal aortic aneurysms. Relation to size and rupture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Involvement of Membrane-Type Matrix Metalloproteinases (MT-MMPs) in Capillary Tube Formation by Human Endometrial Microvascular Endothelial Cells: Role of MT3-MMP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Localization by in situ hybridization of mRNAs encoding stromelysin 3 and tissue inhibitors of metallo-proteinases TIMP-1 and TIMP-2 in human head and neck carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Effect of matrix metalloproteinase inhibition on progression of atherosclerosis and aneurysm in LDL receptor-deficient mice overexpressing MMP-3, MMP-12, and MMP-13 and on restenosis in rats after balloon injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MMP-2 colocalizes with caveolae on the surface of endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Selective inhibition of matrix metalloproteinase-13 increases collagen content of established mouse atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MMP-2 and MMP-9 alteration in response to collaring in rabbits: the effects of endothelin receptor antagonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Diverse patterns of cyclooxygenase-independent metalloproteinase gene regulation in human monocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Increased 18F-fluorodeoxyglucose uptake in abdominal aortic aneurysms in positron emission/computed tomography is associated with inflammation, aortic wall instability, and acute symptoms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-1 reduces atherosclerotic lesions in apolipoprotein E-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Biphenyl sulfonylamino methyl bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix Metalloproteinase Expressions in Arteriosclerotic Aneurysmal Disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Tetracyclines: nonantibiotic properties and their clinical implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix-metalloproteinase-14 deficiency in bone-marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

In vivo optical molecular imaging of matrix metalloproteinase activity in abdominal aortic aneurysms correlates with treatment effects on growth rate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Continuous periaortic infusion improves doxycycline efficacy in experimental aortic aneurysms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Persistence of atherosclerotic plaque but reduced aneurysm formation in mice with stromelysin-1 (MMP-3) gene inactivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Reduced atherosclerotic plaque but enhanced aneurysm formation in mice with inactivation of the tissue inhibitor of metalloproteinase-1 (TIMP-1) gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase 2 is associated with stable and matrix metalloproteinases 8 and 9 with vulnerable carotid atherosclerotic lesions: a study in human endarterectomy specimen pointing to a role for different extracellular matrix metalloprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Early beneficial effect of matrix metalloproteinase inhibition on blood-brain barrier permeability as measured by magnetic resonance imaging countered by impaired long-term recovery after stroke in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Increased secretion of basement membrane-degrading metalloproteinases in pig saphenous vein into carotid artery interposition grafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Novel matrix metalloproteinase inhibitors: generation of lead compounds by the in silico fragment-based approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Analysis of in situ and ex vivo vascular endothelial growth factor receptor expression during experimental aortic aneurysm progression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Cytokines in atherosclerosis: pathogenic and regulatory pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Genomics of Foam Cells and Nonfoamy Macrophages From Rabbits Identifies Arginase-I as a Differential Regulator of Nitric Oxide Production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MMP inhibition in abdominal aortic aneurysms. Rationale for a prospective randomized clinical trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase-2: the forgotten enzyme in aneurysm pathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Marimastat inhibits elastin degradation and matrix metalloproteinase 2 activity in a model of aneurysm disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Elevated expression of matrix metalloproteinase-13 in abdominal aortic aneurysms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

In vivo serial assessment of aortic aneurysm formation in apolipoprotein E-deficient mice via MRI

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Pathology of the vulnerable plaque

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Hepatocyte growth factor enhances MMP activity in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-alpha in cultured human umbilical vein endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCgamma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Role of the Rhoa/Rho kinase system in flow-related remodeling of rat mesenteric small arteries in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase 8 (neutrophil collagenase) in the pathogenesis of abdominal aortic aneurysm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Matrix metalloproteinase-8 and -9 are increased at the site of abdominal aortic aneurysm rupture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Effects of tissue inhibitor of metalloproteinase 2 deficiency on aneurysm formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Membrane-type 1 matrix metalloproteinase regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Enhanced expression of matrix metalloproteinase-9 in abdominal aortic aneurysms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Transcription factor Sp1 phosphorylation induced by shear stress inhibits membrane type 1-matrix metalloproteinase expression in endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.01.007

10.1016/J.VPH.2012.01.007

7 January 2021

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22326338