Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases (Q37976521)

26 August 2017

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases (English)

1 reference

26 August 2017

Christopher J. Schofield

series ordinal

4

1 reference

26 August 2017

Michael A McDonough

3

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author name string

Monica Mantri

series ordinal

1

1 reference

PubMed ID

22251775

26 August 2017

Zhihong Zhang

series ordinal

2

1 reference

PubMed ID

22251775

26 August 2017

language of work or name

English

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publication date

20 February 2012

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26 August 2017

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26 August 2017

279

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26 August 2017

9

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26 August 2017

1563-1575

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FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes

26 August 2017

1 reference

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Expanding chemical biology of 2-oxoglutarate oxygenases

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SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

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Structural and mechanistic studies on γ-butyrobetaine hydroxylase

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The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens

21 January 2018

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Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases

21 January 2018

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Chemistry and biosynthesis of clavulanic acid and other clavams

21 January 2018

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Expression cloning of a gibberellin 20-oxidase, a multifunctional enzyme involved in gibberellin biosynthesis.

21 January 2018

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Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase

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Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

21 January 2018

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Crystal structure and mechanistic implications of 1-aminocyclopropane-1-carboxylic acid oxidase--the ethylene-forming enzyme.

21 January 2018

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Inhibition of 2-oxoglutarate dependent oxygenases

21 January 2018

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Structural studies on human 2-oxoglutarate dependent oxygenases

21 January 2018

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Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins

21 January 2018

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Structure of a cephalosporin synthase

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The 2-His-1-carboxylate facial triad--an emerging structural motif in mononuclear non-heme iron(II) enzymes

21 January 2018

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Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation

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Evidence That Two Enzyme-derived Histidine Ligands Are Sufficient for Iron Binding and Catalysis by Factor Inhibiting HIF (FIH)

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The structural basis of cephalosporin formation in a mononuclear ferrous enzyme

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Dynamic states of the DNA repair enzyme AlkB regulate product release

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Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

21 January 2018

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Selective inhibition of factor inhibiting hypoxia-inducible factor

21 January 2018

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Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements

21 January 2018

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Non-heme Fe(IV)-oxo intermediates

21 January 2018

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Direct detection of oxygen intermediates in the non-heme Fe enzyme taurine/alpha-ketoglutarate dioxygenase.

21 January 2018

1 reference

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Theoretical perspective on the structure and mechanism of cytochrome P450 enzymes.

21 January 2018

1 reference

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Mechanism of oxidation reactions catalyzed by cytochrome p450 enzymes.

21 January 2018

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O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase

21 January 2018

1 reference

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Alternative reactivity of an alpha-ketoglutarate-dependent iron(II) oxygenase: enzyme self-hydroxylation

21 January 2018

1 reference

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Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: single turnover reaction

21 January 2018

1 reference

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The nature of O2 activation by the ethylene-forming enzyme 1-aminocyclopropane-1-carboxylic acid oxidase

21 January 2018

1 reference

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Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue

21 January 2018

1 reference

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Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

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Cytochrome p450 and chemical toxicology

21 January 2018

1 reference

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Destruction of heme and hemoproteins mediated by liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase

21 January 2018

1 reference

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Auto-hydroxylation of FIH-1: an Fe(ii), alpha-ketoglutarate-dependent human hypoxia sensor.

21 January 2018

1 reference

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Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

21 January 2018

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Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage

21 January 2018

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Detection of four oxidation sites in viral prolyl-4-hydroxylase by top-down mass spectrometry.

21 January 2018

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Succinate complex crystal structures of the alpha-ketoglutarate-dependent dioxygenase AtsK: steric aspects of enzyme self-hydroxylation

21 January 2018

1 reference

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Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

21 January 2018

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Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase.

21 January 2018

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Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia coli

21 January 2018

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Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase

21 January 2018

1 reference

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Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions

21 January 2018

1 reference

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Protein oxidation and aging

21 January 2018

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Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis

21 January 2018

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A model for oxidative modification of glutamine synthetase, based on crystal structures of mutant H269N and the oxidized enzyme

21 January 2018

1 reference

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Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents

21 January 2018

1 reference

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Incorporation of oxygen into the succinate co-product of iron(II) and 2-oxoglutarate dependent oxygenases from bacteria, plants and humans

21 January 2018

1 reference

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Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase

21 January 2018

1 reference

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Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

21 January 2018

1 reference

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The 2-Oxoglutarate-Dependent Oxygenase JMJD6 Catalyses Oxidation of Lysine Residues to give 5S-Hydroxylysine Residues

21 January 2018

1 reference

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The most versatile of all reactive intermediates?

21 January 2018

1 reference

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Inactivation of 1-Aminocyclopropane-1-carboxylate Oxidase Involves Oxidative Modifications†

21 January 2018

1 reference

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Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

21 January 2018

1 reference

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10.1111/J.1742-4658.2012.08496.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22251775