Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy? (Q37973820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Joannes F. M. Jacobs

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Stefan Nierkens

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

I Jolanda M de Vries

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Gosse J Adema

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

1 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

Lancet Oncology Commission

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

e32-42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma

19 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Systematic review of medical treatment in melanoma: current status and future prospects.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Immunotherapy for melanoma: current status and perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Human T cell responses against melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Recent advances and hurdles in melanoma immunotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Regulatory T cells and immune tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Human tumor antigen-specific helper and regulatory T cells share common epitope specificity but exhibit distinct T cell repertoire.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Toll-like receptor signalling on Tregs: to suppress or not to suppress?

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Increased regulatory T-cell frequencies in patients with advanced melanoma correlate with a generally impaired T-cell responsiveness and are restored after dendritic cell-based vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Immunosuppressive dendritic and regulatory T cells are upregulated in melanoma patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

FOXP3+ cell density in primary tumor has no prognostic impact in patients with cutaneous malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Evaluation of tumour-infiltrating CD4+CD25+FOXP3+ regulatory T cells in human cutaneous benign and atypical naevi, melanomas and melanoma metastases

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

CD4+CD25+ suppressor lymphocytes in the circulation of patients immunized against melanoma antigens

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Prognostic value of tumor-infiltrating Foxp3+ T-cell subpopulations in metastatic melanoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Leukocyte infiltration and tumor cell plasticity are parameters of aggressiveness in primary cutaneous melanoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Vaccination against the Forkhead Family Transcription Factor Foxp3 Enhances Tumor Immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Regulatory T-cell compartmentalization and trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Skin melanoma development in ret transgenic mice despite the depletion of CD25+Foxp3+ regulatory T cells in lymphoid organs

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Indoleamine 2,3-dioxygenase and tumor-induced tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Blockade of CCL1 inhibits T regulatory cell suppressive function enhancing tumor immunity without affecting T effector responses.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Comparative methodologies of regulatory T cell depletion in a murine melanoma model

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Regulatory T cells in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Interleukin 2 receptor-targeted cytotoxicity. Receptor binding requirements for entry of a diphtheria toxin-related interleukin 2 fusion protein into cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(Hi) regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Toll-like receptor 2 controls expansion and function of regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Plasticity of CD4(+) FoxP3(+) T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2811%2970155-3

7 January 2021

10.1016/S1470-2045(11)70155-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference