Excipients with specialized functions for effective drug delivery (Q37971124)

26 August 2017

Excipients with specialized functions for effective drug delivery (English)

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26 August 2017

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1

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26 August 2017

Jan Steenekamp

2

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language of work or name

English

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publication date

23 December 2011

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Expert Opinion on Drug Delivery

26 August 2017

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26 August 2017

9

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26 August 2017

2

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26 August 2017

219-230

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Excipient selection can significantly affect solid-state phase transformation in formulation during wet granulation

26 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Pharmaceutical excipient development: the need for preclinical guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Novel multifunctional pharmaceutical excipients derived from microcrystalline cellulose-starch microparticulate composites prepared by compatibilized reactive polymer blending

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Intestinal permeation enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Safe and effective permeation enhancers for oral drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

The effects of excipients on transporter mediated absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Difficulties in the production of identical drug products from a pharmaceutical technology viewpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Alternative routes of administration for systemic delivery of protein pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Membrane transporter/receptor-targeted prodrug design: strategies for human and veterinary drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Discovery of tight junction modulators: significance for drug development and delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Transcellular uptake mechanisms of the intestinal epithelial barrier Part one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Effect of chitosan on epithelial permeability and structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Buccal penetration enhancement properties of N-trimethyl chitosan: Influence of quaternization degree on absorption of a high molecular weight molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Transdermal permeation enhancement of N-trimethyl chitosan for testosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Improving drug solubility for oral delivery using solid dispersions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

When poor solubility becomes an issue: from early stage to proof of concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Dissolution behavior of a poorly water soluble compound in the presence of Tween 80

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Solubilizing excipients in oral and injectable formulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Solubilization behavior of a poorly soluble drug under combined use of surfactants and cosolvents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Cyclodextrins as pharmaceutical solubilizers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Pharmaceutical profiling in drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Quality and functionality of excipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

pH control of nucleophilic/electrophilic oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Stabilization of pharmaceuticals to oxidative degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Approaches to improve the stability of the antiviral agent UC781 in aqueous solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Polymeric plant-derived excipients in drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

pH-independent drug release of an extremely poorly soluble weakly acidic drug from multiparticulate extended release formulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Polymers in drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Design and evaluation of matrix-based controlled release tablets of diclofenac sodium and chondroitin sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Guar-based monolithic matrix systems: effect of ionizable and non-ionizable substances and excipients on gel dynamics and release kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

High-amylose carboxymethyl starch matrices for oral sustained drug-release: in vitro and in vivo evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Swelling and erosion of pectin matrix tablets and their impact on drug release behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Effect of oppositely charged polymer and dissolution medium on swelling, erosion, and drug release from chitosan matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Interpolyelectrolyte complexes of Eudragit E PO with sodium alginate as potential carriers for colonic drug delivery: monitoring of structural transformation and composition changes during swellability and release evaluating

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Smart polymers for responsive drug-delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Engineered polymers for advanced drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Enhanced transport of a novel anti-HIV agent--cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Evaluation of absorption enhancement for a potent cyclopeptidic alpha(nu)beta(3)-antagonist in a human intestinal cell line (Caco-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Mechanistic understanding of oral drug absorption enhancement of cromolyn sodium by an amino acid derivative.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

The impact of DeltaG on the oral bioavailability of low bioavailable therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Evaluation of dodecylmaltoside as a permeability enhancer for insulin using human carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Modulation of ganciclovir intestinal absorption in presence of absorption enhancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Complexation hydrogels for oral insulin delivery: effects of polymer dosing on in vivo efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Model prodrugs designed for the intestinal peptide transporter. A synthetic approach for coupling of hydroxy-containing compounds to dipeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

A novel per-oral insulin formulation: proof of concept study in non-diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Paediatric pharmacology: Remember the excipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Preparation of an extended-release matrix tablet using chitosan/Carbopol interpolymer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Responsive polymers in controlled drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Architecture and composition influence on the properties of some smart polymeric materials designed as matrices in drug delivery systems. A comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Drug release from carbomer:carbomer sodium salt matrices with potential use as mucoadhesive drug delivery system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2012.647907

10.1517/17425247.2012.647907

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22196483