Clinical pharmacokinetics of fingolimod (Q37965580)

26 August 2017

Clinical pharmacokinetics of fingolimod (English)

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26 August 2017

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Olivier J David

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26 August 2017

John M Kovarik

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2

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26 August 2017

Robert L Schmouder

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3

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26 August 2017

1 January 2012

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Clinical Pharmacokinetics

26 August 2017

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26 August 2017

51

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26 August 2017

15-28

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https://scigraph.springernature.com/pub.10.2165/11596550-000000000-00000

26 August 2017

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cites work

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

1 reference

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Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis

21 January 2018

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FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system

21 January 2018

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

21 January 2018

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A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.2165%2F11596550-000000000-00000

Single-dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects

21 January 2018

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FTY720 pharmacokinetics in mild to moderate hepatic impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11596550-000000000-00000

Fingolimod (FTY720) in severe hepatic impairment: pharmacokinetics and relationship to markers of liver function

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11596550-000000000-00000

Changes in plasma protein binding have little clinical relevance

21 January 2018

1 reference

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Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study

21 January 2018

1 reference

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Multiple-dose FTY720: tolerability, pharmacokinetics, and lymphocyte responses in healthy subjects

21 January 2018

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FTY720 and cyclosporine: evaluation for a pharmacokinetic interaction

21 January 2018

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Pharmacokinetics, pharmacodynamics, safety, and tolerability of single-dose fingolimod (FTY720) in adolescents with stable renal transplants

21 January 2018

1 reference

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Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11596550-000000000-00000

The effect on heart rate of combining single-dose fingolimod with steady-state atenolol or diltiazem in healthy subjects

21 January 2018

1 reference

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Oral fingolimod (FTY720) for relapsing multiple sclerosis

21 January 2018

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A mechanistic study to assess whether isoproterenol can reverse the negative chronotropic effect of fingolimod

21 January 2018

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The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects

21 January 2018

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CYP4F enzymes are responsible for the elimination of fingolimod (FTY720), a novel treatment of relapsing multiple sclerosis

21 January 2018

1 reference

12 December 2020

Ethnic sensitivity study of fingolimod in white and Asian subjects

1 reference

12 December 2020

First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients

1 reference

12 December 2020

FTY720 story. Its discovery and the following accelerated development of sphingosine 1-phosphate receptor agonists as immunomodulators based on reverse pharmacology

1 reference

12 December 2020

Oral-intravenous crossover study of fingolimod pharmacokinetics, lymphocyte responses and cardiac effects

1 reference

12 December 2020

Exposure-efficacy relationships of a fingolimod-everolimus regimen in kidney transplant patients at risk for delayed graft function

1 reference

12 December 2020

Absorption and disposition of the sphingosine 1-phosphate receptor modulator fingolimod (FTY720) in healthy volunteers: a case of xenobiotic biotransformation following endogenous metabolic pathways

1 reference

12 December 2020

10.2165/11596550-000000000-00000

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DOI

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Dimensions Publication ID

26 August 2017

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