Roles for nuclear organization in the maintenance of genome stability (Q37961727)

26 August 2017

Roles for nuclear organization in the maintenance of genome stability (English)

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26 August 2017

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3

Susan M Gasser

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26 August 2017

Shigeki Nagai

1

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PubMed ID

22121875

26 August 2017

Patrick Heun

series ordinal

2

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26 August 2017

1 April 2010

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26 August 2017

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26 August 2017

2

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26 August 2017

2

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26 August 2017

289-305

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Chromatin motion is constrained by association with nuclear compartments in human cells.

26 August 2017

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Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus.

21 January 2018

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Chromosome dynamics in the yeast interphase nucleus

21 January 2018

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Interphase chromosomes undergo constrained diffusional motion in living cells

21 January 2018

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In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition

21 January 2018

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The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

21 January 2018

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Perinuclear localization of chromatin facilitates transcriptional silencing

21 January 2018

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The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion

21 January 2018

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Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions

21 January 2018

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Transcriptional repression mediated by repositioning of genes to the nuclear lamina

21 January 2018

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A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

21 January 2018

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Recruitment to the nuclear periphery can alter expression of genes in human cells

21 January 2018

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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

21 January 2018

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Characterization of the Drosophila melanogaster genome at the nuclear lamina.

21 January 2018

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Human laminopathies: nuclei gone genetically awry

21 January 2018

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Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

21 January 2018

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Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

21 January 2018

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Nup-PI: the nucleopore-promoter interaction of genes in yeast

21 January 2018

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Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization

21 January 2018

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Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila

21 January 2018

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Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast.

21 January 2018

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Spatial and temporal dynamics of DNA replication sites in mammalian cells

21 January 2018

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Mapping replicational sites in the eucaryotic cell nucleus

21 January 2018

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The positioning and dynamics of origins of replication in the budding yeast nucleus.

21 January 2018

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Ku complex controls the replication time of DNA in telomere regions.

21 January 2018

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Global reorganization of replication domains during embryonic stem cell differentiation

21 January 2018

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The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae

21 January 2018

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Histone acetylation regulates the time of replication origin firing

21 January 2018

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Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing

21 January 2018

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Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae

21 January 2018

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Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome

21 January 2018

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Genome maintenance mechanisms for preventing cancer

21 January 2018

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Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair

21 January 2018

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Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains.

21 January 2018

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Positional stability of single double-strand breaks in mammalian cells

21 January 2018

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Lack of chromosome territoriality in yeast: promiscuous rejoining of broken chromosome ends.

21 January 2018

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Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiae

21 January 2018

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Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase

21 January 2018

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The dynamics of homologous pairing during mating type interconversion in budding yeast

21 January 2018

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Rad52 forms DNA repair and recombination centers during S phase

21 January 2018

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Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage

21 January 2018

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Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

21 January 2018

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Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex

21 January 2018

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In situ visualization of DNA double-strand break repair in human fibroblasts

21 January 2018

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

21 January 2018

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Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

21 January 2018

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Chromosomes are predominantly located randomly with respect to each other in interphase human cells

21 January 2018

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53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

21 January 2018

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DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

21 January 2018

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Finding a match: how do homologous sequences get together for recombination?

21 January 2018

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The frequency of gene targeting in yeast depends on the number of target copies

21 January 2018

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Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair

21 January 2018

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Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

21 January 2018

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INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

21 January 2018

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Chromatin dynamics and the preservation of genetic information

21 January 2018

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Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks.

21 January 2018

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Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae

21 January 2018

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A chromatin remodelling complex involved in transcription and DNA processing.

21 January 2018

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Computational modeling of the chromatin fiber

21 January 2018

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Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations

21 January 2018

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Chromosome pairing does not contribute to nuclear architecture in vegetative yeast cells

21 January 2018

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Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells

21 January 2018

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Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei

21 January 2018

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Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast

21 January 2018

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Yeast nuclei display prominent centromere clustering that is reduced in nondividing cells and in meiotic prophase

21 January 2018

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Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization

21 January 2018

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From early homologue recognition to synaptonemal complex formation

21 January 2018

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Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast

21 January 2018

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Chromosome topology in mammalian interphase nuclei

21 January 2018

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SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

21 January 2018

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In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway

21 January 2018

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The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences

21 January 2018

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Active genes dynamically colocalize to shared sites of ongoing transcription

21 January 2018

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Myc dynamically and preferentially relocates to a transcription factory occupied by Igh

21 January 2018

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Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins.

21 January 2018

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Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning

21 January 2018

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Gene recruitment of the activated INO1 locus to the nuclear membrane

21 January 2018

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The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator

21 January 2018

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CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

21 January 2018

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Functional TFIIH is required for UV-induced translocation of CSA to the nuclear matrix

21 January 2018

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Sub-nuclear localization of Rad51 in response to DNA damage.

21 January 2018

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A SIM-ultaneous role for SUMO and ubiquitin

21 January 2018

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Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery

21 January 2018

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Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break

21 January 2018

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Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination

21 January 2018

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The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

21 January 2018

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Telomeres and their control

21 January 2018

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Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML.

21 January 2018

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RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

21 January 2018

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Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

21 January 2018

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Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

21 January 2018

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Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence

21 January 2018

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Break-induced replication and recombinational telomere elongation in yeast

21 January 2018

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The DNA damage response at eroded telomeres and tethering to the nuclear pore complex.

21 January 2018

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A two-step model for senescence triggered by a single critically short telomere

21 January 2018

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Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

21 January 2018

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Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

21 January 2018

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Yeast ribosomal DNA genes are located on chromosome XII

21 January 2018

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Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

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Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I

21 January 2018

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Cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S. cerevisiae

21 January 2018

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The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus.

21 January 2018

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Mutational analysis of the structure and localization of the nucleolus in the yeast Saccharomyces cerevisiae

21 January 2018

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Role for perinuclear chromosome tethering in maintenance of genome stability.

21 January 2018

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Karyopherin-mediated import of integral inner nuclear membrane proteins

21 January 2018

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A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

21 January 2018

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Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.

21 January 2018

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Nuclear microenvironments in biological control and cancer.

21 January 2018

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Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides

21 January 2018

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Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

21 January 2018

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Nuclear pore association confers optimal expression levels for an inducible yeast gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/EPI.09.49

1 reference

26 August 2017

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PubMed ID

22121875