Role of glial cells in manganese neurotoxicity (Q37961543)

26 August 2017

Role of glial cells in manganese neurotoxicity (English)

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26 August 2017

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Nikolay M Filipov

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26 August 2017

Celia A Dodd

series ordinal

2

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26 August 2017

language of work or name

English

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publication date

26 November 2011

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Journal of Applied Toxicology

26 August 2017

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26 August 2017

32

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26 August 2017

5

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26 August 2017

310-317

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Mild steel welding fume causes manganese accumulation and subtle neuroinflammatory changes but not overt neuronal damage in discrete brain regions of rats after short-term inhalation exposure

26 August 2017

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Nutritional aspects of manganese homeostasis.

21 January 2018

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Manganese: pharmacokinetics and molecular mechanisms of brain uptake

21 January 2018

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Manganese dosimetry: species differences and implications for neurotoxicity

21 January 2018

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Manganese: recent advances in understanding its transport and neurotoxicity

21 January 2018

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Manganese and its role in Parkinson's disease: from transport to neuropathology

21 January 2018

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Manganese induces inducible nitric oxide synthase (iNOS) expression via activation of both MAP kinase and PI3K/Akt pathways in BV2 microglial cells

21 January 2018

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Entry of blood-borne cytokines into the central nervous system: effects on cognitive processes

21 January 2018

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Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB.

21 January 2018

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Early-life infection is a vulnerability factor for aging-related glial alterations and cognitive decline

21 January 2018

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Early-life programming of later-life brain and behavior: a critical role for the immune system

21 January 2018

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

21 January 2018

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Dose-effect relationships between manganese exposure and neurological, neuropsychological and pulmonary function in confined space bridge welders

21 January 2018

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Manganese potentiates nitric oxide production by microglia

21 January 2018

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Manganese modulates pro-inflammatory gene expression in activated glia

21 January 2018

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Reactive astrocytes as potential manipulation targets in novel cell replacement therapy of Parkinson's disease

21 January 2018

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Manganese-induced potentiation of in vitro proinflammatory cytokine production by activated microglial cells is associated with persistent activation of p38 MAPK.

21 January 2018

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Manganese modulation of MAPK pathways: effects on upstream mitogen activated protein kinase kinases and mitogen activated kinase phosphatase-1 in microglial cells

21 January 2018

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21 January 2018

Manganese neurotoxicity

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Manganese potentiates LPS-induced heme-oxygenase 1 in microglia but not dopaminergic cells: role in controlling microglial hydrogen peroxide and inflammatory cytokine output

21 January 2018

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Neurotoxicity of manganese chloride in neonatal and adult CD rats following subchronic (21-day) high-dose oral exposure.

21 January 2018

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Sub-chronic inhalation of high concentrations of manganese sulfate induces lower airway pathology in rhesus monkeys

21 January 2018

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Rat brain endothelial cells are a target of manganese toxicity

21 January 2018

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Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

21 January 2018

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Interactions between excessive manganese exposures and dietary iron-deficiency in neurodegeneration

21 January 2018

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Manganese neurotoxicity: a focus on the neonate

21 January 2018

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Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism

21 January 2018

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A chronic iron-deficient/high-manganese diet in rodents results in increased brain oxidative stress and behavioral deficits in the morris water maze.

21 January 2018

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Changes in dietary iron exacerbate regional brain manganese accumulation as determined by magnetic resonance imaging

21 January 2018

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Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity

21 January 2018

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Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates

21 January 2018

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Oxidative basis of manganese neurotoxicity

21 January 2018

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Astrocytes and manganese neurotoxicity

21 January 2018

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Manganese decreases glutamate uptake in cultured astrocytes

21 January 2018

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Ammonia and manganese increase arginine uptake in cultured astrocytes.

21 January 2018

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Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment

21 January 2018

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Nitric oxide, mitochondria and neurological disease

21 January 2018

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Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion

21 January 2018

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Preweaning Mn exposure leads to prolonged astrocyte activation and lasting effects on the dopaminergic system in adult male rats

21 January 2018

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Dopamine transporter SPECT of a liver cirrhotic with atypical parkinsonism.

21 January 2018

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Oxidative stress and mitochondrial-mediated apoptosis in dopaminergic cells exposed to methylcyclopentadienyl manganese tricarbonyl

21 January 2018

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Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.

21 January 2018

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Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

21 January 2018

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Dopamine quinones activate microglia and induce a neurotoxic gene expression profile: relationship to methamphetamine-induced nerve ending damage

21 January 2018

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Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.

21 January 2018

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Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

21 January 2018

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Estrogen and tamoxifen protect against Mn-induced toxicity in rat cortical primary cultures of neurons and astrocytes

21 January 2018

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Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.

21 January 2018

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Role of nitric oxide in inflammation-mediated neurodegeneration.

21 January 2018

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Effect of microglia activation on dopaminergic neuronal injury induced by manganese, and its possible mechanism.

21 January 2018

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NF-kappaB-dependent production of nitric oxide by astrocytes mediates apoptosis in differentiated PC12 neurons following exposure to manganese and cytokines

21 January 2018

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Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degeneration

21 January 2018

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Mechanism of neurobehavioral alteration

21 January 2018

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Antioxidants prevent the cytotoxicity of manganese in RBE4 cells

21 January 2018

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Glial reactions in Parkinson's disease

21 January 2018

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Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

21 January 2018

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Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signaling pathways

21 January 2018

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Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration

21 January 2018

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Manganese-induced NF-kappaB activation and nitrosative stress is decreased by estrogen in juvenile mice

21 January 2018

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Etiology and pathogenesis of Parkinson's disease

21 January 2018

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The neuropathology of manganese-induced Parkinsonism

21 January 2018

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The impact of systemic infection on the progression of neurodegenerative disease.

21 January 2018

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Molecular mechanism of manganese exposure-induced dopaminergic toxicity

21 January 2018

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α-Synuclein overexpression enhances manganese-induced neurotoxicity through the NF-κB-mediated pathway

21 January 2018

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Activation of early signaling transcription factor, NF-kappaB following low-level manganese exposure

21 January 2018

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Early onset of virus infection and up-regulation of cytokines in mice treated with cadmium and manganese

21 January 2018

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Direct effects of manganese compounds on dopamine and its metabolite Dopac: an in vitro study

21 January 2018

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Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

21 January 2018

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Differential regulation of glutamic acid decarboxylase mRNA and tyrosine hydroxylase mRNA expression in the aged manganese-treated rats.

21 January 2018

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Effects of neonatal dietary manganese exposure on brain dopamine levels and neurocognitive functions

21 January 2018

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Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates.

21 January 2018

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Activation of activator protein-1 DNA binding activity due to low level manganese exposure in pheochromocytoma cells.

21 January 2018

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21 January 2018

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Manganese chloride stimulates rat microglia to release hydrogen peroxide

21 January 2018

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Microglia enhance manganese chloride-induced dopaminergic neurodegeneration: role of free radical generation

21 January 2018

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Synergistic dopaminergic neurotoxicity of manganese and lipopolysaccharide: differential involvement of microglia and astroglia

21 January 2018

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Effect of manganese chloride exposure on liver and brain mitochondria function in rats

21 January 2018

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Manganese induces dopaminergic neurodegeneration via microglial activation in a rat model of manganism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JAT.1762

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release_aq2wujnq3bdkzfnu3gn3r6khxe

26 August 2017

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24 November 2022

based on heuristic

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