Molecular pathogenesis of pancreatic cancer and clinical perspectives (Q37960816)

26 August 2017

Molecular pathogenesis of pancreatic cancer and clinical perspectives (English)

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26 August 2017

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D Matthaios

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26 August 2017

P Zarogoulidis

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26 August 2017

I Balgouranidou

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26 August 2017

E Chatzaki

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26 August 2017

S Kakolyris

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26 August 2017

language of work or name

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23 November 2011

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26 August 2017

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26 August 2017

81

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26 August 2017

3-4

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26 August 2017

259-272

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Molecular characterization of pancreatic neoplasms

26 August 2017

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Nonductal neoplasms of the pancreas

21 January 2018

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Increased Risk of Cancer Other Than Melanoma in CDKN2A Founder Mutation (p16-Leiden)-Positive Melanoma Families

21 January 2018

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Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis

21 January 2018

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Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy

21 January 2018

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Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation

21 January 2018

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SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

21 January 2018

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Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness

21 January 2018

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Abrogation of signal transducer and activator of transcription 3 reactivation after Src kinase inhibition results in synergistic antitumor effects

21 January 2018

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STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas

21 January 2018

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LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

21 January 2018

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Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF

21 January 2018

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Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

21 January 2018

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MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer

21 January 2018

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Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

21 January 2018

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Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity

21 January 2018

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Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs

21 January 2018

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Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms

21 January 2018

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Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma

21 January 2018

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The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis

21 January 2018

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Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines

21 January 2018

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Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer

21 January 2018

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Abrogation of DUSP6 by hypermethylation in human pancreatic cancer

21 January 2018

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Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms

21 January 2018

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Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions

21 January 2018

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An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

21 January 2018

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Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

21 January 2018

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Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas.

21 January 2018

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Diagnosing pancreatic cancer using methylation specific PCR analysis of pancreatic juice.

21 January 2018

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Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions

21 January 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

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Differential methylation of cell-free circulating DNA among patients with pancreatic cancer versus chronic pancreatitis

21 January 2018

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 January 2018

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Roles and mechanisms of microRNAs in pancreatic cancer

21 January 2018

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Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

21 January 2018

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miR-301a as an NF-κB activator in pancreatic cancer cells

21 January 2018

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LNA-mediated microRNA silencing in non-human primates

21 January 2018

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The let-7 microRNA represses cell proliferation pathways in human cells

21 January 2018

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Implication of microRNAs in drug resistance for designing novel cancer therapy

21 January 2018

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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

21 January 2018

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Development and characterization of gemcitabine-resistant pancreatic tumor cells.

21 January 2018

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Survival of cancer cells is maintained by EGFR independent of its kinase activity

21 January 2018

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Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

21 January 2018

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Prognostic significance of activated Akt expression in pancreatic ductal adenocarcinoma

21 January 2018

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The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells

21 January 2018

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Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

21 January 2018

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Role of Akt in growth and survival of PANC-1 pancreatic cancer cells

21 January 2018

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BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer

21 January 2018

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CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer.

21 January 2018

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PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells

21 January 2018

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A new mouse model of pancreatic cancer: PTEN gets its Akt together

21 January 2018

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

21 January 2018

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Genome profiling of pancreatic adenocarcinoma

21 January 2018

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Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer

21 January 2018

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Intracranial granulocytic sarcoma after chemotherapy for pineal germinoma and testicular cancer

21 January 2018

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Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces or

21 January 2018

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Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model

21 January 2018

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Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

21 January 2018

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HIF-1: an oxygen and metal responsive transcription factor

21 January 2018

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CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer

21 January 2018

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The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis.

21 January 2018

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The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia.

21 January 2018

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Chemokine receptor CXCR4 enhances proliferation in pancreatic cancer cells through AKT and ERK dependent pathways.

21 January 2018

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

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The hedgehog signaling network

21 January 2018

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Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

21 January 2018

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HSP90 and the chaperoning of cancer

21 January 2018

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Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer.

21 January 2018

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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 January 2018

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

21 January 2018

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000334449

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26 August 2017

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