Modulation of ion channels in clinical psychopharmacology: adults and younger people (Q37960095)

25 August 2017

Modulation of ion channels in clinical psychopharmacology: adults and younger people (English)

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25 August 2017

Lindsey I Sinclair

1

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25 August 2017

Peter T Dineen

series ordinal

2

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25 August 2017

Andrea L Malizia

series ordinal

3

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25 August 2017

language of work or name

English

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publication date

1 May 2010

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Expert Review of Clinical Pharmacology

25 August 2017

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25 August 2017

3

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25 August 2017

397-416

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25 August 2017

3

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Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

25 August 2017

1 reference

From ion channels to complex networks: magic bullet versus magic shotgun approaches to anticonvulsant pharmacotherapy.

21 January 2018

1 reference

The mechanisms of action of commonly used antiepileptic drugs

21 January 2018

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GABAA receptors as targets for novel anxiolytic drugs

21 January 2018

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A new benzodiazepine pharmacology.

21 January 2018

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The pharmacokinetic and pharmacodynamic effects of SL65.1498, a GABA-A alpha2,3 selective agonist, in comparison with lorazepam in healthy volunteers

21 January 2018

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GABA-ergic drugs: exit stage left, enter stage right

21 January 2018

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The diagnosis and management of benzodiazepine dependence

21 January 2018

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Peripheral-type benzodiazepine receptors in anxiety disorders.

21 January 2018

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Decreased density of benzodiazepine receptors in lymphocytes of anxious patients: reversal after chronic diazepam treatment.

21 January 2018

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Peripheral benzodiazepine binding sites on platelet membranes are increased during diazepam treatment of anxious patients.

21 January 2018

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New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder

21 January 2018

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Reduced gamma-aminobutyric acid(A)-benzodiazepine binding sites in insular cortex of individuals with panic disorder.

21 January 2018

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Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography

21 January 2018

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Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.

21 January 2018

1 reference

Antidepressant-induced jitteriness/anxiety syndrome: systematic review.

21 January 2018

1 reference

Therapeutic drug monitoring of alprazolam in adolescents with asthma.

21 January 2018

1 reference

Clinical, cognitive, and neurophysiological effects of alprazolam in children and adolescents with overanxious and avoidant disorders

21 January 2018

1 reference

Neuroleptic malignant syndrome in a child treated with an atypical antipsychotic

21 January 2018

1 reference

Ziprasidone monotherapy in pediatric bipolar disorder

21 January 2018

1 reference

Zuclopenthixol-induced neuroleptic malignant syndrome in an adolescent girl.

21 January 2018

1 reference

Catatonia in autism: implications across the life span

21 January 2018

1 reference

A naturalistic evaluation of intramuscular ziprasidone versus intramuscular olanzapine for the management of acute agitation and aggression in children and adolescents

21 January 2018

1 reference

Serotonin syndrome following a single 50 mg dose of sertraline in a child.

21 January 2018

1 reference

A16-year-old girl with excited catatonia treated with low-dose oral Lorazepam

21 January 2018

1 reference

The effectiveness of a pain and anxiety protocol to treat the acute pediatric burn patient

21 January 2018

1 reference

Tiagabine in anxiety disorders

21 January 2018

1 reference

Molecular targets in the treatment of anxiety

21 January 2018

1 reference

Effects of tiagabine on cholecystokinin-tetrapeptide (CCK-4)-induced anxiety in healthy volunteers

21 January 2018

1 reference

Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies

21 January 2018

1 reference

Tiagabine for posttraumatic stress disorder: effects of open-label and double-blind discontinuation treatment

21 January 2018

1 reference

The efficacy and tolerability of tiagabine in adult patients with post-traumatic stress disorder

21 January 2018

1 reference

Tiagabine for social anxiety disorder

21 January 2018

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Tiagabine: efficacy and safety in partial seizures - current status

21 January 2018

1 reference

Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment

21 January 2018

1 reference

Vigabatrin has an anxiolytic effect in the elevated plus-maze test of anxiety

21 January 2018

1 reference

Anxiolytic-like effect of the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA) on rat exploratory activity.

21 January 2018

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Vigabatrin and tiagabine might have antipanic properties

21 January 2018

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Vigabatrin decreases cholecystokinin-tetrapeptide (CCK-4) induced panic in healthy volunteers

21 January 2018

1 reference

Evaluation of the abuse potential of pagoclone, a partial GABAA agonist

21 January 2018

1 reference

Divalproex in the treatment of posttraumatic stress disorder: a randomized, double-blind, placebo-controlled trial in a veteran population

21 January 2018

1 reference

Valproate treatment of panic disorder and lactate-induced panic attacks.

21 January 2018

1 reference

Ketter's hypothesis of the mood effects of antiepileptic drugs coupled to the mechanism of action of topiramate and levetiracetam

21 January 2018

1 reference

Cognitive and psychiatric effects of topiramate monotherapy in migraine treatment: an open study

21 January 2018

1 reference

Effects of Topiramate on Aggressive, Self-Injurious, and Disruptive/Destructive Behaviors in the Intellectually Disabled: An Open-Label Retrospective Study

21 January 2018

1 reference

Adjuvant topiramate administration: a pharmacologic strategy for addressing NMDA receptor hypofunction in schizophrenia

21 January 2018

1 reference

Efficacy of topiramate in bulimia nervosa and binge-eating disorder: a systematic review

21 January 2018

1 reference

Reversible dementia secondary to topiramate

21 January 2018

1 reference

Topiramate for treating alcohol dependence: a randomized controlled trial

21 January 2018

1 reference

Topiramate add-on treatment in schizophrenia: a randomised, double-blind, placebo-controlled clinical trial

21 January 2018

1 reference

Worsening of psychosis or topiramate-induced adverse event?

21 January 2018

1 reference

Donepezil treatment of topiramate-related cognitive dysfunction.

21 January 2018

1 reference

Topiramate-induced psychosis

21 January 2018

1 reference

Topiramate-induced psychosis in patients with essential tremor: report of 2 cases.

21 January 2018

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Oral topiramate for treatment of alcohol dependence: a randomised controlled trial

21 January 2018

1 reference

Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings

21 January 2018

1 reference

Prospective open-label study of add-on and monotherapy topiramate in civilians with chronic nonhallucinatory posttraumatic stress disorder

21 January 2018

1 reference

A randomized, double-blind, placebo-controlled trial of augmentation topiramate for chronic combat-related posttraumatic stress disorder

21 January 2018

1 reference

A randomized, double-blind, placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic stress disorder

21 January 2018

1 reference

Topiramate augmentation in treatment-resistant obsessive-compulsive disorder: a retrospective, open-label case series

21 January 2018

1 reference

Evidence-based guidelines for the pharmacological management of substance misuse, addiction and comorbidity: recommendations from the British Association for Psychopharmacology.

21 January 2018

1 reference

Using topiramate or naltrexone for the treatment of alcohol-dependent patients

21 January 2018

1 reference

Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees

21 January 2018

1 reference

A pilot trial of topiramate for the treatment of cocaine dependence

21 January 2018

1 reference

Trazodone and valproate in patients discontinuing long-term benzodiazepine therapy: effects on withdrawal symptoms and taper outcome

21 January 2018

1 reference

Topiramate in benzodiazepine withdrawal

21 January 2018

1 reference

Topiramate use in alprazolam addiction.

21 January 2018

1 reference

Topiramate in opiate withdrawal

21 January 2018

1 reference

The effects of flumazenil, Ro 154513 and beta-CCM on the behaviour of control and stressed mice in the staircase test

21 January 2018

1 reference

Effects of naltrexone and Ro 15-4513 on a multiple schedule of ethanol and Tang self-administration

21 January 2018

1 reference

Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography

21 January 2018

1 reference

RO 15-4513 and its interaction with ethanol

21 January 2018

1 reference

Topiramate for the treatment of kleptomania: a case series and review of the literature

21 January 2018

1 reference

Topiramate versus fluvoxamine in the treatment of pathological gambling: a randomized, blind-rater comparison study

21 January 2018

1 reference

12-month follow-up study of drug treatment in pathological gamblers: a primary outcome study

21 January 2018

1 reference

Compulsive buying treatment with topiramate, a case report

21 January 2018

1 reference

Treatment of paraphilic sexual disorder: the use of topiramate in fetishism.

21 January 2018

1 reference

Topiramate in the treatment of trichotillomania: an open-label pilot study

21 January 2018

1 reference

GABA and glutamate systems as therapeutic targets in depression and mood disorders

21 January 2018

1 reference

A preliminary metabolomic analysis of older adults with and without depression.

21 January 2018

1 reference

Plasma GABA levels in psychiatric illness

21 January 2018

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Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors

21 January 2018

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Increased cortical GABA concentrations in depressed patients receiving ECT.

21 January 2018

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21 January 2018

GABA and mood disorders.

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Benzodiazepines as antidepressants: does GABA play a role in depression?

21 January 2018

1 reference

Paradoxical reactions to benzodiazepines

21 January 2018

1 reference

Pharmacological interventions for the prevention of relapse in bipolar disorder: a systematic review of controlled trials

21 January 2018

1 reference

Medication use in children and adolescents treated in the community for bipolar disorder

21 January 2018

1 reference

A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents

21 January 2018

1 reference

A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy

21 January 2018

1 reference

Vigabatrin and depression

21 January 2018

1 reference

How reviews covered the unfolding scientific story of gabapentin for bipolar disorder

21 January 2018

1 reference

Gabapentin and methylphenidate treatment of a preadolescent with attention deficit hyperactivity disorder and bipolar disorder

21 January 2018

1 reference

Gabapentin augmentation therapy in bipolar depression

21 January 2018

1 reference

Topiramate monotherapy in the management of acute mania: results of four double-blind placebo-controlled trials

21 January 2018

1 reference

A pilot study of topiramate as monotherapy in the treatment of acute mania

21 January 2018

1 reference

Topiramate and divalproex in combination with risperidone for acute mania: a randomized open-label study

21 January 2018

1 reference

Adjunctive topiramate in the maintenance treatment of bipolar disorders: an open-label study

21 January 2018

1 reference

Use of topiramate, a new anti-epileptic as a mood stabilizer.

21 January 2018

1 reference

Topiramate versus bupropion SR when added to mood stabilizer therapy for the depressive phase of bipolar disorder: a preliminary single-blind study

21 January 2018

1 reference

Topiramate-induced depression

21 January 2018

1 reference

Adjunctive topiramate in hospitalized children and adolescents with bipolar disorders

21 January 2018

1 reference

A pilot controlled trial of topiramate for mania in children and adolescents with bipolar disorder

21 January 2018

1 reference

Topiramate in treatment of depressive and anger symptoms in female depressive patients: a randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

Topiramate in treatment-resistant depression and binge-eating disorder

21 January 2018

1 reference

Primidone and rapid cycling affective disorders

21 January 2018

1 reference

Treating insomnia: Current and investigational pharmacological approaches

21 January 2018

1 reference

Potential pharmacokinetic basis for zolpidem dosing in children with sleep difficulties

21 January 2018

1 reference

Controlled clinical trial of zolpidem for the treatment of insomnia associated with attention-deficit/ hyperactivity disorder in children 6 to 17 years of age.

21 January 2018

1 reference

Anxiolytics, hypnotics, and antidepressants dispensed to adolescents in a French region in 2002

21 January 2018

1 reference

Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia

21 January 2018

1 reference

Pouring oil into the fire? On the conundrum of the beneficial effects of NMDA receptor antagonists in Alzheimer disease

21 January 2018

1 reference

Anticonvulsants in the treatment of aggression in the demented elderly: an update

21 January 2018

1 reference

Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats

21 January 2018

1 reference

Effects of antiepileptic drugs on attention as assessed by a five-choice serial reaction time task in rats

21 January 2018

1 reference

GABA(A) receptor subtype-selective efficacy: TPA023, an alpha2/alpha3 selective non-sedating anxiolytic and alpha5IA, an alpha5 selective cognition enhancer

21 January 2018

1 reference

An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

21 January 2018

1 reference

Blockade of alcohol's amnestic activity in humans by an alpha5 subtype benzodiazepine receptor inverse agonist.

21 January 2018

1 reference

Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA alpha5 inverse agonists with potential for the treatment of cognitive dysfunction

21 January 2018

1 reference

The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction

21 January 2018

1 reference

Critical review of GABA-ergic drugs in the treatment of schizophrenia

21 January 2018

1 reference

GABA and Schizophrenia: A Review of Basic Science and Clinical Studies

21 January 2018

1 reference

GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.

21 January 2018

1 reference

A revised excitotoxic hypothesis of schizophrenia: therapeutic implications

21 January 2018

1 reference

GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.

21 January 2018

1 reference

Reduced cortical inhibition in first-episode schizophrenia.

21 January 2018

1 reference

Pathophysiologically based treatment interventions in schizophrenia

21 January 2018

1 reference

Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction

21 January 2018

1 reference

Inhibitory deficit in schizophrenia is not necessarily a GABAergic deficit

21 January 2018

1 reference

Rapid tranquilization: new approaches in the emergency treatment of behavioral disturbances

21 January 2018

1 reference

Rapid tranquillisation. A survey of emergency prescribing in a general psychiatric hospital

21 January 2018

1 reference

The expert consensus guideline series. Treatment of behavioral emergencies 2005.

21 January 2018

1 reference

Topiramate as an adjuvant treatment with atypical antipsychotics in schizophrenic patients experiencing weight gain

21 January 2018

1 reference

Topiramate effect in catatonia: a case series

21 January 2018

1 reference

The current status of tardive dyskinesia.

21 January 2018

1 reference

GABA agonist-induced changes in motor, oculomotor, and attention measures correlate in schizophrenics with tardive dyskinesia

21 January 2018

1 reference

21 January 2018

Vigabatrin and psychosis

1 reference

Topiramate treatment of women with borderline personality disorder, part II: an open 18-month follow-up

21 January 2018

1 reference

Topiramate for self-mutilation in a patient with borderline personality disorder

21 January 2018

1 reference

Calcium-channel blockade and depressive illness

21 January 2018

1 reference

Calcium-channel blockade and depressive illness.

21 January 2018

1 reference

Verapamil treatment for women with bipolar disorder

21 January 2018

1 reference

Pregabalin augmentation to antidepressants in patients with major depressive disorder.

21 January 2018

1 reference

Verapamil augmentation of lithium treatment improves outcome in mania unresponsive to lithium alone: preliminary findings and a discussion of therapeutic mechanisms

21 January 2018

1 reference

Verapamil and valproic acid treatment of prolonged mania.

21 January 2018

1 reference

Calcium channel antagonists for the treatment of bipolar disorder

21 January 2018

1 reference

Adjunctive pregabalin to quetiapine in acute mania.

21 January 2018

1 reference

Long-term efficacy of pregabalin in generalized anxiety disorder

21 January 2018

1 reference

Pregabalin for the treatment of generalized anxiety disorder: a novel pharmacologic intervention

21 January 2018

1 reference

Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials.

21 January 2018

1 reference

Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder

21 January 2018

1 reference

Pregabalin in generalized anxiety disorder: a placebo-controlled trial

21 January 2018

1 reference

Pregabalin for treatment of generalized anxiety disorder: a 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam

21 January 2018

1 reference

Pregabalin: From molecule to medicine

21 January 2018

1 reference

Pregabalin for the treatment of generalised anxiety disorder

21 January 2018

1 reference

Pregabalin augmentation of antidepressants in patients with accident-related posttraumatic stress disorder: an open label pilot study

21 January 2018

1 reference

An effect-size analysis of pharmacologic treatments for generalized anxiety disorder

21 January 2018

1 reference

Pregabalin treatment of posttraumatic stress disorder

21 January 2018

1 reference

Pregabalin augmentation to sertraline-risperidone combination in the treatment of obsessive-compulsive disorder

21 January 2018

1 reference

The efficacy of pregabalin and benzodiazepines in generalized anxiety disorder presenting with high levels of insomnia

21 January 2018

1 reference

Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study

21 January 2018

1 reference

Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy.

21 January 2018

1 reference

Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.

21 January 2018

1 reference

Nimodipine in opiate detoxification: a controlled trial.

21 January 2018

1 reference

Nimodipine in human alcohol withdrawal syndrome--an open study

21 January 2018

1 reference

Calcium channel antagonists decrease the ethanol withdrawal syndrome.

21 January 2018

1 reference

Efficacy and safety of pregabalin in alcohol dependence

21 January 2018

1 reference

The N-type calcium channel is a novel target for treating alcohol use disorders

21 January 2018

1 reference

A blocker of N- and T-type voltage-gated calcium channels attenuates ethanol-induced intoxication, place preference, self-administration, and reinstatement

21 January 2018

1 reference

Phenytoin as an augmentation for SSRI failures: a small controlled study

21 January 2018

1 reference

Prophylactic effect of phenytoin in bipolar disorder: a controlled study

21 January 2018

1 reference

Lamotrigine and the treatment of mania in bipolar disorder

21 January 2018

1 reference

Discovery and development of lamotrigine for bipolar disorder: a story of serendipity, clinical observations, risk taking, and persistence

21 January 2018

1 reference

Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials

21 January 2018

1 reference

Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder

21 January 2018

1 reference

Anticonvulsants in the treatment of major depressive disorder: an overview

21 January 2018

1 reference

Comparison of carbamazepine and lithium in treatment of bipolar disorder: a systematic review of randomized controlled trials

21 January 2018

1 reference

Potentiation of antidepressants with lithium or carbamazepine in treatment-resistant depression.

21 January 2018

1 reference

Identification of treatment-resistant depressives who respond favorably to carbamazepine.

21 January 2018

1 reference

Carbamazepine augmentation in depressive patients non-responding to citalopram: a pharmacokinetic and clinical pilot study

21 January 2018

1 reference

A prospective open-label trial of extended-release carbamazepine monotherapy in children with bipolar disorder.

21 January 2018

1 reference

A comparison of divalproex and oxcarbazepine in aggressive youth with bipolar disorder

21 January 2018

1 reference

The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis

21 January 2018

1 reference

Placebo-controlled trial of intravenous diphenylhydantoin for short-term treatment of alcohol withdrawal seizures

21 January 2018

1 reference

Phenytoin in the treatment of cocaine abuse: a double-blind study.

21 January 2018

1 reference

Adjunctive treatment of benzodiazepine discontinuation syndromes: a review

21 January 2018

1 reference

Lamotrigine for agitation in older patients with dementia

21 January 2018

1 reference

Randomised controlled study-efficacy of clonidine versus carbamazepine in children with ADHD.

21 January 2018

1 reference

Drug treatment of conduct disorder in young people

21 January 2018

1 reference

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels

21 January 2018

1 reference

Structure and regulation of voltage-gated Ca2+ channels

21 January 2018

1 reference

Mood stabilization and weight loss with topiramate.

21 January 2018

1 reference

The Selective GABA Reuptake Inhibitor Tiagabine for the Treatment of Generalized Anxiety Disorder

21 January 2018

1 reference

Pregabalin in Patients With Antidepressant Treatment-Resistant Somatoform Disorders

21 January 2018

1 reference

Combination therapy with venlafaxine and carbamazepine in depressive patients not responding to venlafaxine: pharmacokinetic and clinical aspects

21 January 2018

1 reference

The Effects of Topiramate Adjunctive Treatment Added to Antidepressants in Patients with Resistant Obsessive-compulsive Disorder

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ECP.10.21

1 reference

25 August 2017

1 reference