Sirtuin 1 in immune regulation and autoimmunity (Q37959305)

25 August 2017

Sirtuin 1 in immune regulation and autoimmunity (English)

1 reference

25 August 2017

Sinyi Kong

1

1 reference

PubMed ID

22105513

25 August 2017

Michael W McBurney

series ordinal

2

1 reference

PubMed ID

22105513

25 August 2017

Deyu Fang

series ordinal

3

1 reference

25 August 2017

22 November 2011

1 reference

Immunology & Cell Biology

25 August 2017

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25 August 2017

90

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25 August 2017

1

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25 August 2017

6-13

1 reference

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

25 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 regulates the function of the Nijmegen breakage syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Inhibition of transcriptional activity of c-JUN by SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

RETRACTED: Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

miR-34a repression of SIRT1 regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

JNK1 phosphorylates SIRT1 and promotes its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

JNK2-dependent regulation of SIRT1 protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

DBC1 is a negative regulator of SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Negative regulation of the deacetylase SIRT1 by DBC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Introduction to NF-kappaB: players, pathways, perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Circuitry of nuclear factor kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

The type III histone deacetylase Sirt1 protein suppresses p300-mediated histone H3 lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Plasma cell differentiation requires the transcription factor XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

XBP-1 couples endoplasmic reticulum stress to augmented IFN-beta induction via a cis-acting enhancer in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Roles of SIRT1 in the acute and restorative phases following induction of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Essential role for Bclaf1 in lung development and immune system function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

STAT3 inhibition of gluconeogenesis is downregulated by SirT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Transcriptional mechanisms underlying lymphocyte tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Binding of Tat to TAR and recruitment of positive transcription elongation factor b occur independently in bovine immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

SIRT1 regulates HIV transcription via Tat deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Effects of resveratrol in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Resveratrol is a class IA phosphoinositide 3-kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Involvement of sirtuin 1 in airway inflammation and hyperresponsiveness of allergic airway disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

7 January 2021

Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

7 January 2021

sirt1-null mice develop an autoimmune-like condition

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

7 January 2021

Transcriptional regulation in the immune system: all roads lead to AP-1.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

7 January 2021

IgG1 production by sIgD+ splenic B cells and peritoneal B-1 cells in response to IL-5 and CD38 ligation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.102

7 January 2021

Identifiers

DOI

10.1038/ICB.2011.102

1 reference

25 August 2017

1 reference

PubMed ID

22105513