Evolution of microRNA diversity and regulation in animals (Q37957677)

25 August 2017

Evolution of microRNA diversity and regulation in animals (English)

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25 August 2017

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25 August 2017

18 November 2011

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25 August 2017

Nature Reviews Genetics

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25 August 2017

12

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25 August 2017

846-860

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25 August 2017

12

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https://scigraph.springernature.com/pub.10.1038/nrg3079

25 August 2017

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

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An extensive class of small RNAs in Caenorhabditis elegans

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Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals

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Ancient animal microRNAs and the evolution of tissue identity

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The expansion of the metazoan microRNA repertoire

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MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion

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MicroRNAs and the advent of vertebrate morphological complexity

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The deep evolution of metazoan microRNAs

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microRNAs reveal the interrelationships of hagfish, lampreys, and gnathostomes and the nature of the ancestral vertebrate

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Evolutionary flux of canonical microRNAs and mirtrons in Drosophila

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Diversity of microRNAs in human and chimpanzee brain.

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Canalization of development by microRNAs

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The phylogenetic distribution of metazoan microRNAs: insights into evolutionary complexity and constraint

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Evolutionary conservation of microRNA regulatory circuits: an examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogeny

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Evidence for a microRNA expansion in the bilaterian ancestor

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The evolution of gene regulation by transcription factors and microRNAs

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A uniform system for microRNA annotation

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miRBase: integrating microRNA annotation and deep-sequencing data

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Simultaneous expansions of microRNAs and protein-coding genes by gene/genome duplications in early vertebrates.

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Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs

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Identification of mammalian microRNA host genes and transcription units

31 March 2020

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Expression patterns of intronic microRNAs in Caenorhabditis elegans

31 March 2020

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Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity

31 March 2020

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Chromatin structure analyses identify miRNA promoters

31 March 2020

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The birth and death of microRNA genes in Drosophila.

31 March 2020

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Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

31 March 2020

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Primate microRNAs miR-220 and miR-492 lie within processed pseudogenes

31 March 2020

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A human snoRNA with microRNA-like functions

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Human miRNA precursors with box H/ACA snoRNA features

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Regulatory RNAs derived from transfer RNA?

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Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs

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Identification of human miRNA precursors that resemble box C/D snoRNAs

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Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin.

31 March 2020

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Molecular domestication of transposable elements: from detrimental parasites to useful host genes.

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The impact of retrotransposons on human genome evolution

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Mammalian microRNAs derived from genomic repeats

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A family of human microRNA genes from miniature inverted-repeat transposable elements

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Marsupial-specific microRNAs evolved from marsupial-specific transposable elements

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Origin and evolution of a placental-specific microRNA family in the human genome

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MicroRNA genes derived from repetitive elements and expanded by segmental duplication events in mammalian genomes

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miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

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31 March 2020

The many faces of RNAi

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MicroRNAs in the Drosophila bithorax complex

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A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands

31 March 2020

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Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci

31 March 2020

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Identification of hundreds of conserved and nonconserved human microRNAs

31 March 2020

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

31 March 2020

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The evolution and functional diversification of animal microRNA genes

31 March 2020

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Adaptive evolution of newly emerged micro-RNA genes in Drosophila

31 March 2020

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Adverse interactions between micro-RNAs and target genes from different species

31 March 2020

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miRNA profiling of naïve, effector and memory CD8 T cells.

31 March 2020

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A mammalian microRNA expression atlas based on small RNA library sequencing

31 March 2020

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Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

31 March 2020

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Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies.

31 March 2020

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Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

31 March 2020

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Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

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Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans

31 March 2020

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A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness

31 March 2020

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Dynamic isomiR regulation in Drosophila development

31 March 2020

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The microRNAs of Caenorhabditis elegans

31 March 2020

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MicroRNAs: target recognition and regulatory functions

31 March 2020

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Functional shifts in insect microRNA evolution

31 March 2020

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MicroRNAs: genomics, biogenesis, mechanism, and function

31 March 2020

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The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution

31 March 2020

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Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells

31 March 2020

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Repertoire and evolution of miRNA genes in four divergent nematode species

31 March 2020

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MicroRNA evolution by arm switching

31 March 2020

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Functional siRNAs and miRNAs Exhibit Strand Bias

31 March 2020

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Asymmetry in the assembly of the RNAi enzyme complex

31 March 2020

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Tissue-dependent paired expression of miRNAs

31 March 2020

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Editor meets silencer: crosstalk between RNA editing and RNA interference

31 March 2020

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RNA editing of a miRNA precursor

31 March 2020

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RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex

31 March 2020

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Redirection of silencing targets by adenosine-to-inosine editing of miRNAs

31 March 2020

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Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

31 March 2020

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The Effect of RNA Editing and ADARs on miRNA Biogenesis and Function

31 March 2020

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Tracing the evolution of tissue identity with microRNAs

31 March 2020

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Differences in vertebrate microRNA expression

31 March 2020

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Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development

31 March 2020

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Desperately seeking microRNA targets

31 March 2020

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Prediction of mammalian microRNA targets

31 March 2020

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Principles of microRNA-target recognition

31 March 2020

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Combinatorial microRNA target predictions

31 March 2020

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

31 March 2020

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Most mammalian mRNAs are conserved targets of microRNAs

31 March 2020

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MicroRNA targeting specificity in mammals: determinants beyond seed pairing

31 March 2020

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Expanding the microRNA targeting code: functional sites with centered pairing

31 March 2020

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Isolation of microRNA targets by miRNP immunopurification

31 March 2020

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Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

31 March 2020

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miR-148 targets human DNMT3b protein coding region

31 March 2020

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A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

31 March 2020

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MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

31 March 2020

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MicroRNA-126 regulates HOXA9 by binding to the homeobox

31 March 2020

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MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

31 March 2020

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CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation

31 March 2020

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Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRs

31 March 2020

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MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions

31 March 2020

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Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

31 March 2020

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The impact of miRNA target sites in coding sequences and in 3'UTRs

31 March 2020

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The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

31 March 2020

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Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

31 March 2020

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Specificity of microRNA target selection in translational repression

31 March 2020

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Determinants of targeting by endogenous and exogenous microRNAs and siRNAs

31 March 2020

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Distance constraints between microRNA target sites dictate efficacy and cooperativity

31 March 2020

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Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

31 March 2020

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Cell-type-specific signatures of microRNAs on target mRNA expression

31 March 2020

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Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

31 March 2020

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Alternative isoform regulation in human tissue transcriptomes

31 March 2020

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Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

31 March 2020

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Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

31 March 2020

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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.

31 March 2020

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A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

31 March 2020

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Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression

31 March 2020

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Natural selection on human microRNA binding sites inferred from SNP data

31 March 2020

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Human polymorphism at microRNAs and microRNA target sites

31 March 2020

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An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset

31 March 2020

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A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

31 March 2020

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A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk

31 March 2020

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Functional SNP in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification

31 March 2020

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Adaptive evolution and explosive speciation: the cichlid fish model

31 March 2020

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Evolution of microRNAs and the diversification of species

31 March 2020

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MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems

31 March 2020

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Nature, nurture, or chance: stochastic gene expression and its consequences

31 March 2020

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Biological principles of microRNA-mediated regulation: shared themes amid diversity

31 March 2020

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

31 March 2020

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Targets of microRNA regulation in the Drosophila oocyte proteome

31 March 2020

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Widespread changes in protein synthesis induced by microRNAs

31 March 2020

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The impact of microRNAs on protein output

31 March 2020

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MicroRNAs can generate thresholds in target gene expression

31 March 2020

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MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals

31 March 2020

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Evolution under canalization and the dual roles of microRNAs: a hypothesis

31 March 2020

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MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila

31 March 2020

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A microRNA imparts robustness against environmental fluctuation during development

31 March 2020

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Most Caenorhabditis elegans microRNAs are individually not essential for development or viability

31 March 2020

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Many families of C. elegans microRNAs are not essential for development or viability

31 March 2020

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Loss of individual microRNAs causes mutant phenotypes in sensitized genetic backgrounds in C. elegans

31 March 2020

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MicroRNAs: genetically sensitized worms reveal new secrets

31 March 2020

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The relationship between non-protein-coding DNA and eukaryotic complexity.

31 March 2020

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Deep conservation of microRNA-target relationships and 3'UTR motifs in vertebrates, flies, and nematodes

31 March 2020

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Approaches to microRNA discovery

31 March 2020

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Discovering microRNAs from deep sequencing data using miRDeep

31 March 2020

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The Trichoplax genome and the nature of placozoans

31 March 2020

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

31 March 2020

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MicroRNA genes are transcribed by RNA polymerase II

31 March 2020

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Processing of intronic microRNAs

31 March 2020

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Processing of primary microRNAs by the Microprocessor complex

31 March 2020

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The Microprocessor complex mediates the genesis of microRNAs

31 March 2020

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Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

31 March 2020

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31 March 2020

Mammalian mirtron genes

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The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila

31 March 2020

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Intronic microRNA precursors that bypass Drosha processing

31 March 2020

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MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila

31 March 2020

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Role for a bidentate ribonuclease in the initiation step of RNA interference

31 March 2020

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

31 March 2020

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

31 March 2020

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

31 March 2020

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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

31 March 2020

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Canalization in evolutionary genetics: a stabilizing theory?

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22094948

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRG3079

1 reference

25 August 2017

1 reference

PubMed ID

22094948