Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds (Q37954617)

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scientific article published on 24 October 2011

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English	Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds	scientific article published on 24 October 2011

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scholarly article

1 reference

Europe PubMed Central

25 August 2017

2 references

4 November 2019

18 November 2019

Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds (English)

1 reference

Europe PubMed Central

25 August 2017

1 reference

4 November 2019

1 reference

18 November 2019

1 reference

based on heuristic

inferred from title

Marcel Tutor Ale

object named as

Marcel Tutor Ale

1

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Anne Strunge Meyer

object named as

Anne S Meyer

3

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author name string

Jørn D Mikkelsen

2

1 reference

Europe PubMed Central

25 August 2017

publication date

24 October 2011

3 references

Europe PubMed Central

25 August 2017

4 November 2019

18 November 2019

3 references

Europe PubMed Central

25 August 2017

4 November 2019

18 November 2019

9

1 reference

Europe PubMed Central

25 August 2017

10

1 reference

Europe PubMed Central

25 August 2017

2106-2130

1 reference

Europe PubMed Central

25 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

2 references

Europe PubMed Central

4 November 2019

Europe PubMed Central

18 November 2019

copyright status

0 references

Chemical structures and bioactivities of sulfated polysaccharides from marine algae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

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Future scenarios for the treatment of advanced non-small cell lung cancer: focus on taxane-containing regimens.

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6 September 2017

Fucoidan present in brown algae induces apoptosis of human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Structural analysis of a fucoidan from the brown alga Fucus evanescens by MALDI-TOF and tandem ESI mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Fucoidan: structure and bioactivity.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Structural investigation of a fucoidan containing a fucose-free core from the brown seaweed, Hizikia fusiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Fucoidan induces apoptosis of human HS-sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives

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6 September 2017

Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Searching for alternatives to heparin: sulfated fucans from marine invertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Further data on the structure of brown seaweed fucans: relationships with anticoagulant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

The role of natural killer cells in human disease

1 reference

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6 September 2017

Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

6 September 2017

Relationship between oversulfation and conformation of low and high molecular weight fucoidans and evaluation of their in vitro anticancer activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

14 September 2017

Fucoidan induces apoptosis through activation of caspase-8 on human breast cancer MCF-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

14 September 2017

Structural characteristics and in vitro macrophage activation of acetyl fucoidan from Cladosiphon okamuranus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

14 September 2017

A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

14 September 2017

The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

14 September 2017

Isolation and characterization of a sulfated polysaccharide from the brown alga Sargassum patens and determination of its anti-herpes activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

14 September 2017

Relationship between sulfate groups and biological activities of fucans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

28 September 2017

On the nature of the cell wall constituents of Laminaria spp. Mannuronic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

23 June 2018

A revised structure for fucoidan may explain some of its biological activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

23 June 2018

Inhibitory effect of oversulfated fucoidan on invasion through reconstituted basement membrane by murine Lewis lung carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

23 June 2018

The influence of sulfate content and molecular weight of a fucan sulfate from the brown seaweed Ecklonia kurome on its antithrombin activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

23 June 2018

Low molecular weight fucoidan prevents intimal hyperplasia in rat injured thoracic aorta through the modulation of matrix metalloproteinase-2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Higher specificity of the activity of low molecular weight fucoidan for thrombin-induced platelet aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Effect of fucoidan on the biotinidase kinetics in human hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk Sea Fucus evanescens brown alga.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Characterization of a fucoidan from Lessonia vadosa (Phaeophyta) and its anticoagulant and elicitor properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Structure of a fucoidan from the brown seaweed Fucus serratus L.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Structural and hemostatic activities of a sulfated galactofucan from the brown alga Spatoglossum schroederi. An ideal antithrombotic agent?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Fucoidan inhibits the development of proteinuria in active Heymann nephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Structure of a fucoidan from the brown seaweed Fucus evanescens C.Ag

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

A fucoidan fraction from Ascophyllum nodosum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210621

1 September 2018

Designed optimization of a single-step extraction of fucose-containing sulfated polysaccharides from Sargassum sp

1 reference

https://api.crossref.org/works/10.3390%2FMD9102106

21 January 2018

Degradative Studies on Fucoidin1

1 reference

https://api.crossref.org/works/10.3390%2FMD9102106

21 January 2018

Enzymic Degradation of Fucoidan by Fucoidanase from the Hepatopancreas of Patinopecten yessoensis.

1 reference

https://api.crossref.org/works/10.3390%2FMD9102106

21 January 2018

A 2-sulfated, 3-linked α-l-galactan is an anticoagulant polysaccharide

1 reference

https://api.crossref.org/works/10.3390%2FMD9102106

21 January 2018

Structure and anticoagulant activity of sulfated fucans. Comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of fucoidan from the brown seaweed Chorda filum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural study of fucoidan from Cladosiphon okamuranus TOKIDA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of anticoagulant fractions from crude fucoidin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An anticoagulant fucoidan from the brown seaweed Ecklonia kurome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal peroxidative changes mediated by oxalate: the protective role of fucoidan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Polysaccharides of algae: 60. Fucoidan from the Pacific brown alga Analipus japonicus (Harv.) Winne (Ectocarpales, Scytosiphonaceae)]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sulfate-content dependence of the anticoagulant activity of a fucan sulfate from the brown seaweed Ecklonia kurome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Antiviral activity of sulfated polysaccharide from the brown algae Laminaria japonica against avian influenza A (H5N1) virus infection in the cultured cells]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fucoidan film safely inhibits surgical adhesions in a rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-response relationship for lung cancer induction at radiotherapy dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulatory activity of fucoidan against aspirin-induced gastric mucosal damage in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and preliminary characterization of fucose-containing sulfated polysaccharides with blood-anticoagulant activity from the brown seaweed Hizikia fusiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation, purification, and characterization of fucose-containing sulfated polysaccharides from the brown seaweed Ecklonia kurome and their blood-anticoagulant activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New natural polysaccharides with potent antithrombic activity: fucans from brown algae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effect of seaweeds. I. Antitumor effect of extracts from Sargassum and Laminaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effect of seaweeds. III. Antitumor effect of an extract from Sargassum kjellmanianum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oversulfated fucoidan and heparin suppress endotoxin induction of plasminogen activator inhibitor-1 in cultured human endothelial cells: their possible mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and partial characterization of a novel amino sugar-containing fucan sulfate from commercial Fucus vesiculosus fucoidan

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sulfated alpha-L-fucan from sea cucumber

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Sulfated polysaccharides as inhibitors of receptor activity of P-selectin and P-selectin-dependent inflammation]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22073012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MD9102106

1 reference

Europe PubMed Central

25 August 2017

1 reference

Europe PubMed Central

25 August 2017

1 reference

Europe PubMed Central

25 August 2017

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