WWP1: a versatile ubiquitin E3 ligase in signaling and diseases (Q37952498)

25 August 2017

title

WWP1: a versatile ubiquitin E3 ligase in signaling and diseases (English)

1 reference

25 August 2017

Xu Zhi

1

1 reference

25 August 2017

Ceshi Chen

series ordinal

2

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25 August 2017

publication date

4 November 2011

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Cellular and Molecular Life Sciences

25 August 2017

published in

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25 August 2017

volume

69

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25 August 2017

issue

9

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25 August 2017

page(s)

1425-1434

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The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The Nedd4-like family of E3 ubiquitin ligases and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Regulation of functional diversity within the Nedd4 family by accessory and adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Characterization of a novel protein-binding module--the WW domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

NeW wrinkles for an old domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Regulation of the nuclear localization of the human Nedd4-related WWP1 protein by Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Overexpression of WWP1 is associated with the estrogen receptor and insulin-like growth factor receptor 1 in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Reg IV: a promising marker of hormone refractory metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Multiple cell-type-specific elements regulate Myc protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Association of Wwox with ErbB4 in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WWP1-dependent ubiquitination and degradation of the lung Krüppel-like factor, KLF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

In vivo interference of Rous sarcoma virus budding by cis expression of a WW domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

The role of WWP1-Gag interaction and Gag ubiquitination in assembly and release of human T-cell leukemia virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Multiple interactions between the ESCRT machinery and arrestin-related proteins: implications for PPXY-dependent budding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Molecular pathology of dentatorubral-pallidoluysian atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Identification and structural mechanism for a novel interaction between a ubiquitin ligase WWP1 and Nogo-A, a key inhibitor for central nervous system regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

Identification of novel human WW domain-containing proteins by cloning of ligand targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0871-7

SPG20 is mutated in Troyer syndrome, an hereditary spastic paraplegia.

21 January 2018

1 reference

12 December 2020

Differential expression and localisation of WWP1, a Nedd4-like protein, in epithelia

1 reference

12 December 2020

The ubiquitin ligase gene (WWP1) is responsible for the chicken muscular dystrophy

1 reference

12 December 2020

The amplified WWP1 gene is a potential molecular target in breast cancer

1 reference

12 December 2020

Tumour-promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicator

1 reference

12 December 2020

The WWP1 ubiquitin E3 ligase increases TRAIL resistance in breast cancer

1 reference

12 December 2020

A conserved ubiquitination pathway determines longevity in response to diet restriction

1 reference

12 December 2020

10.1007/S00018-011-0871-7

Identifiers

DOI

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release_xtmxcfq4ibcdzidagu55f7xf2i

25 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/xtmxcfq4ibcdzidagu55f7xf2i

24 November 2022

mapped directly with Wikidata item

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