CD95-mediated cell signaling in cancer: mutations and post-translational modulations (Q37951369)

25 August 2017

CD95-mediated cell signaling in cancer: mutations and post-translational modulations (English)

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25 August 2017

4

Patrick Legembre

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25 August 2017

Sébastien Tauzin

1

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25 August 2017

Laure Debure

series ordinal

2

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25 August 2017

Jean-François Moreau

series ordinal

3

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25 August 2017

1 November 2011

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Cellular and Molecular Life Sciences

25 August 2017

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25 August 2017

69

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25 August 2017

8

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25 August 2017

1261-1277

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https://scigraph.springernature.com/pub.10.1007/s00018-011-0866-4

25 August 2017

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cites work

Structure of the human APO-1 gene.

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

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Monoclonal antibody-mediated tumor regression by induction of apoptosis.

21 January 2018

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Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas involvement in cytotoxicity mediated by human NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Regulation of the proinflammatory effects of Fas ligand (CD95L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

CD95 promotes tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Yes and PI3K bind CD95 to signal invasion of glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The Fas-FADD death domain complex structure unravels signalling by receptor clustering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The origin of CD95-gene mutations in B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The relevance of NF-kappaB for CD95 signaling in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas receptor clustering and involvement of the death receptor pathway in rituximab-mediated apoptosis with concomitant sensitization of lymphoma B cells to fas-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Actin-independent exclusion of CD95 by PI3K/AKT signalling: implications for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Redistribution of CD95 into the lipid rafts to treat cancer cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

S-nitrosylation of the death receptor fas promotes fas ligand-mediated apoptosis in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Palmitoylation is required for efficient Fas cell death signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The role of receptor internalization in CD95 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Malignancy after transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Dominant-negative Fas mutation is reversed by down-expression of c-FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Two CD95 tumor classes with different sensitivities to antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Sustained polymorphonuclear leukocyte transmigration induces apoptosis in T84 intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Modulation of the immune response using dendritic cell-derived exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Germline FAS gene mutation in a case of ALPS and NLP Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Autoimmune lymphoproliferative syndrome with somatic Fas mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Somatic FAS mutations are common in patients with genetically undefined autoimmune lymphoproliferative syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas gene mutation in the progression of adult T cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Loss of Fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas gene mutations in prostatic intraepithelial neoplasia and concurrent carcinoma: analysis of laser capture microdissected specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Frequent Fas gene mutations in testicular germ cell tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Infrequent Fas mutations but no Bax or p53 mutations in early mycosis fungoides: a possible mechanism for the accumulation of malignant T lymphocytes in the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Frequent mutations of Fas gene in nasal NK/T cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Mutations within the 5' region of FAS/CD95 gene in nodal diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

FAS mRNA editing in Human Systemic Lupus Erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Ceramide-mediated clustering is required for CD95-DISC formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Solution NMR Investigation of the CD95/FADD Homotypic Death Domain Complex Suggests Lack of Engagement of the CD95 C Terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

21 January 2018

12 December 2020

A role for CD95 ligand in preventing graft rejection

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0866-4

Serum levels of soluble Fas ligand in patients with silicosis

21 January 2018

1 reference

12 December 2020

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

12 December 2020

Defective apoptosis due to a point mutation in the death domain of CD95 associated with autoimmune lymphoproliferative syndrome, T-cell lymphoma, and Hodgkin's disease

1 reference

12 December 2020

Alterations of Fas (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder

1 reference

12 December 2020

Frequent mutations of Fas gene in thyroid lymphoma.

1 reference

12 December 2020

Mutations in the Fas antigen in patients with multiple myeloma.

1 reference

12 December 2020

Chronic lymphadenopathy simulating malignant lymphoma

1 reference

12 December 2020

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen

1 reference

12 December 2020

Autoimmune lymphoproliferative syndrome (ALPS) in a patient with a new germline Fas gene mutation

1 reference

12 December 2020

Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma.

1 reference

12 December 2020

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis

1 reference

12 December 2020

Soluble Fas ligand in the joints of patients with rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

12 December 2020

Levels of soluble FasL and FasL gene expression during the development of graft-versus-host disease in DLT-treated patients

1 reference

12 December 2020

Somatic mutations of the CD95 gene in Hodgkin and Reed-Sternberg cells

1 reference

12 December 2020

Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity.

1 reference

12 December 2020

Increased soluble Fas-ligand in sera of bone marrow transplant recipients with acute graft-versus-host disease

1 reference

12 December 2020

ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

1 reference

12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

1 reference

12 December 2020

The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis

1 reference

12 December 2020

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

1 reference

12 December 2020

Fas ligand in human serum

1 reference

12 December 2020

Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Stromelysin-1 (MMP-3) in synovial fluid of patients with rheumatoid arthritis has potential to cleave membrane bound Fas ligand

1 reference

12 December 2020

Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar

1 reference

12 December 2020

Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations

1 reference

12 December 2020

Does CD95 have tumor promoting activities?

1 reference

12 December 2020

10.1007/S00018-011-0866-4

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DOI

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release_yij52cirn5dm3ogqm2a6jmkufa

25 August 2017

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https://api.fatcat.wiki/v0/release/yij52cirn5dm3ogqm2a6jmkufa

24 November 2022

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