PRDM proteins: important players in differentiation and disease (Q37949547)

25 August 2017

PRDM proteins: important players in differentiation and disease (English)

1 reference

25 August 2017

Cathrine K Fog

1

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Anders H. Lund

object named as

Anders H Lund

series ordinal

3

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author name string

Giorgio G Galli

series ordinal

2

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PubMed ID

22028065

25 August 2017

language of work or name

English

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publication date

26 October 2011

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25 August 2017

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25 August 2017

34

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25 August 2017

50-60

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25 August 2017

1

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Histone methyltransferases, diet nutrients and tumour suppressors

25 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Structural Biology of Human H3K9 Methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The PR/SET domain in PRDM4 is preceded by a zinc knuckle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

A histone H3 methyltransferase controls epigenetic events required for meiotic prophase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Involvement of histone demethylase LSD1 in Blimp-1-mediated gene repression during plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Keep your fingers off my DNA: protein-protein interactions mediated by C2H2 zinc finger domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM16 controls a brown fat/skeletal muscle switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Germ cell specification in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Blimp1 is a critical determinant of the germ cell lineage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Transcriptional control of brown fat development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Transcriptional control of brown fat determination by PRDM16

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Expression of the mouse PR domain protein Prdm8 in the developing central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Expression patterns of PRDM10 during mouse embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Hematopoiesis: an evolving paradigm for stem cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The Evi1 proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Significant increase of self-renewal in hematopoietic cells after forced expression of EVI1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

EVI1 induces myelodysplastic syndrome in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Point mutations in two EVI1 Zn fingers abolish EVI1-GATA1 interaction and allow erythroid differentiation of murine bone marrow cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

EVI1 Impairs myelopoiesis by deregulation of PU.1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Prdm16 is a physiologic regulator of hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

A functional screen to identify novel effectors of hematopoietic stem cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Regulation of plasma-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Cytokines in the differentiation therapy of leukemia: from laboratory investigations to clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Epigenetic down-regulation of the tumor suppressor gene PRDM1/Blimp-1 in diffuse large B cell lymphomas: a potential role of the microRNA let-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Blimp1 is limiting for transformation in a mouse plasmacytoma model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Identification of a functionally impaired positive regulatory domain I binding factor 1 transcription repressor in myeloma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Loss of promoter methylation contributes to the expression of functionally impaired PRDM1β isoform in diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The oncogene and developmental regulator EVI1: expression, biochemical properties, and biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

RIZ1 repression is associated with insulin-like growth factor-1 signaling activation in chronic myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

A histone methyltransferase is required for maximal response to female sex hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM5 is silenced in human cancers and has growth suppressive activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

DNA methylation and carcinogenesis of PRDM5 in cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Wnt/beta-catenin signaling in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The zinc finger SET domain gene Prdm14 is overexpressed in lymphoblastic lymphomas with retroviral insertions at Evi32.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Gene amplification and overexpression of PRDM14 in breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

B lymphocyte-induced maturation protein (Blimp)-1, IFN regulatory factor (IRF)-1, and IRF-2 can bind to the same regulatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Stage-specific modulation of IFN-regulatory factor 4 function by Krüppel-type zinc finger proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

EVI1 recruits the histone methyltransferase SUV39H1 for transcription repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The oncoprotein EVI1 and the DNA methyltransferase Dnmt3 co-operate in binding and de novo methylation of target DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Repression of RUNX1 activity by EVI1: a new role of EVI1 in leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

UXT interacts with the transcriptional repressor protein EVI1 and suppresses cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

Identification of a DNA Binding Protein Cooperating with Estrogen Receptor as RIZ (Retinoblastoma Interacting Zinc Finger Protein)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100107

21 January 2018

Identifiers

DOI

10.1002/BIES.201100107

1 reference

25 August 2017

1 reference

PubMed ID

22028065