Why is chromosome segregation error in oocytes increased with maternal aging? (Q37947557)

25 August 2017

Why is chromosome segregation error in oocytes increased with maternal aging? (English)

1 reference

25 August 2017

2

Heide Schatten

1 reference

25 August 2017

Zhen-Bo Wang

1

1 reference

PubMed ID

22013190

25 August 2017

Qing-Yuan Sun

series ordinal

3

1 reference

25 August 2017

1 October 2011

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25 August 2017

1 reference

25 August 2017

26

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25 August 2017

5

1 reference

25 August 2017

314-325

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Insulin signaling in mouse oocytes.

25 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Cohesin SMC1beta protects telomeres in meiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Regulation of histone acetylation during meiotic maturation in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Inadequate histone deacetylation during oocyte meiosis causes aneuploidy and embryo death in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Maternal age and risk for trisomy 21 assessed by the origin of chromosome nondisjunction: a report from the Atlanta and National Down Syndrome Projects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Meiosis I in human oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Functionality of the spindle checkpoint during the first meiotic division of mammalian oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Regulation of chromatin and chromosome morphology by histone H3 modifications in pig oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Bisphenol-A induces cell cycle delay and alters centrosome and spindle microtubular organization in oocytes during meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Sorting out chromosome errors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Increasing age influences uterine integrity, but not ovarian function or oocyte quality, in the cheetah (Acinonyx jubatus).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changes in histone modifications during in vitro maturation of porcine oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Involvement of Mitogen-Activated Protein Kinase Cascade During Oocyte Maturation and Fertilization in Mammals1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Gene expression profiles of single human mature oocytes in relation to age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Distribution and expression of phosphorylated histone H3 during porcine oocyte maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Mps1 at kinetochores is essential for female mouse meiosis I

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

The origin of human aneuploidy: where we have been, where we are going

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

To err (meiotically) is human: the genesis of human aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Experimental evidence that changes in oocyte growth influence meiotic chromosome segregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

SMC1beta-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

New insights into the genetic regulation of homologue disjunction in mammalian oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Restaging the spindle assembly checkpoint in female mammalian meiosis I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Frequency of aneuploidy related to age in porcine oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changes in histone acetylation during postovulatory aging of mouse oocyte.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Analysis of chromosome behavior in intact mammalian oocytes: monitoring the segregation of a univalent chromosome during female meiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Human female meiosis: what makes a good egg go bad?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Bisphenol a exposure causes meiotic aneuploidy in the female mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

The bisphenol A experience: a primer for the analysis of environmental effects on mammalian reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

A model system for increased meiotic nondisjunction in older oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Increased zona pellucida thickness and meiotic spindle disruption in oocytes from cigarette smoking mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Deterioration without replenishment--the misery of oocyte cohesin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Germline stem cells and follicular renewal in the postnatal mammalian ovary

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Meiosis in oocytes: predisposition to aneuploidy and its increased incidence with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Alterations in epigenetic modifications during oocyte growth in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

The teratogenic effects of alcohol following exposure during pregnancy, and its influence on the chromosome constitution of the pre-ovulatory egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changes in histone acetylation during mouse oocyte meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Female and male lifestyle habits and IVF: what is known and unknown

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Resolution of chiasmata in oocytes requires separase-mediated proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Effect of meiotic recombination on the production of aneuploid gametes in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Association between maternal age and meiotic recombination for trisomy 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Gene expression in the fetal mouse ovary is altered by exposure to low doses of bisphenol A

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Lack of checkpoint control at the metaphase/anaphase transition: a mechanism of meiotic nondisjunction in mammalian females

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Continuous exposure to bisphenol A during in vitro follicular development induces meiotic abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Irregular telomeres impair meiotic synapsis and recombination in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Nuclear origin of aging-associated meiotic defects in senescence-accelerated mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Reduced expression of MAD2, BCL2, and MAP kinase activity in pig oocytes after in vitro aging are associated with defects in sister chromatid segregation during meiosis II and embryo fragmentation after activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Faulty spindle checkpoint and cohesion protein activities predispose oocytes to premature chromosome separation and aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Oocyte aging: cellular and molecular changes, developmental potential and reversal possibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Sister-chromatid cohesion in mitosis and meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Effects of selected endocrine disruptors on meiotic maturation, cumulus expansion, synthesis of hyaluronan and progesterone by porcine oocyte-cumulus complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

The spindle-assembly checkpoint in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changes in H3K79 methylation during preimplantation development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Differential remodeling of mono- and trimethylated H3K27 during porcine embryo development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Chromosomal abnormalities in oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Cohesin component dynamics during meiotic prophase I in mammalian oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changes in histone methylation during human oocyte maturation and IVF- or ICSI-derived embryo development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Epigenetic modifications and related mRNA expression during bovine oocyte in vitro maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Oocyte cohesin expression restricted to predictyate stages provides full fertility and prevents aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Keeping sister chromatids together: cohesins in meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Dynamic alterations of specific histone modifications during early murine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Relationship of recombination patterns and maternal age among non-disjoined chromosomes 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Association between spindle assembly checkpoint expression and maternal age in human oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Post-ovulatory aging of mouse oocytes leads to decreased MAD2 transcripts and increased frequencies of premature centromere separation and anaphase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Aging predisposes oocytes to meiotic nondisjunction when the cohesin subunit SMC1 is reduced

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Heterochromatin-mediated association of achiasmate homologs declines with age when cohesion is compromised

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Bisphenol A exposure in utero disrupts early oogenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Proper chromatin condensation and maintenance of histone H3 phosphorylation during mouse oocyte meiosis requires protein phosphatase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Dynamic changes in histone acetylation during sheep oocyte maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Roles for transforming growth factor beta superfamily proteins in early folliculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Acetaldehyde and microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Human exposure to bisphenol A (BPA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Evidence of a high proportion of premature unbalanced separation of sister chromatids in the first polar bodies of women of advanced age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Spindle formation, chromosome segregation and the spindle checkpoint in mammalian oocytes and susceptibility to meiotic error

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

The meiotic competence of in-vitro matured human oocytes is influenced by donor age: evidence that folliculogenesis is compromised in the reproductively aged ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Histone phosphorylation and pericentromeric histone modifications in oocyte meiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Histone deacetylation is required for orderly meiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Glycogen synthase kinase-3 regulates mouse oocyte homologue segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

A molecular model for sporadic human aneuploidy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Metaphase I arrest upon activation of the Mad2-dependent spindle checkpoint in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Maternal age and trisomy--a unifying mechanism of formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Structure and function of the PP2A-shugoshin interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Shugoshin1 may play important roles in separation of homologous chromosomes and sister chromatids during mouse oocyte meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Bub1 prevents chromosome misalignment and precocious anaphase during mouse oocyte meiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Smoking and reproduction: gene damage to human gametes and embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Localization of mitotic arrest deficient 1 (MAD1) in mouse oocytes during the first meiosis and its functions as a spindle checkpoint protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

Production of offspring from a germline stem cell line derived from neonatal ovaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00020.2011

10.1152/PHYSIOL.00020.2011

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

22013190