Antibiotics as probes of biological complexity (Q37891661)

24 August 2017

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title

Antibiotics as probes of biological complexity (English)

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24 August 2017

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Shannon B Falconer

1

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PubMed ID

21685879

24 August 2017

Tomasz L Czarny

series ordinal

2

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PubMed ID

21685879

24 August 2017

Eric D Brown

series ordinal

3

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24 August 2017

1 July 2011

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24 August 2017

Nature Chemical Biology

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24 August 2017

7

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24 August 2017

7

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24 August 2017

415-423

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https://scigraph.springernature.com/pub.10.1038/nchembio.590

24 August 2017

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cites work

Penicillin-binding proteins and cell shape in E. coli

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Penicillin-sensitive enzymes and penicillin-binding components in bacterial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Bacterial actin MreB assembles in complex with cell shape protein RodZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Regulation of peptidoglycan synthesis by outer-membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

DNA gyrase: an enzyme that introduces superhelical turns into DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

The twisted 'life' of DNA in the cell: bacterial topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Structural Insights into the Quinolone Resistance Mechanism of Mycobacterium tuberculosis DNA Gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Type IIA topoisomerase inhibition by a new class of antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Probing translation with small-molecule inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

INHIBITION BY PUROMYCIN OF AMINO ACID INCORPORATION INTO PROTEIN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

A posttermination ribosomal complex is the guanine nucleotide exchange factor for peptide release factor RF3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Translation factors direct intrinsic ribosome dynamics during translation termination and ribosome recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

A complex between initiation factor IF2, guanosine triphosphate, and fMet-tRNA: an intermediate in initiation complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Ribosome rescue by Escherichia coli ArfA (YhdL) in the absence of trans-translation system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Recycling of aborted ribosomal 50S subunit-nascent chain-tRNA complexes by the heat shock protein Hsp15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Precise alignment of peptidyl tRNA by the decoding center is essential for EF-G-dependent translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

SOS response induction by beta-lactams and bacterial defense against antibiotic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

A common mechanism of cellular death induced by bactericidal antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Bacterial charity work leads to population-wide resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Secretion of LamB-LacZ by the signal recognition particle pathway of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

The surprising complexity of signal sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Diverse paths to midcell: assembly of the bacterial cell division machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Probing teichoic acid genetics with bioactive molecules reveals new interactions among diverse processes in bacterial cell wall biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Precise deletion of tagD and controlled depletion of its product, glycerol 3-phosphate cytidylyltransferase, leads to irregular morphology and lysis of Bacillus subtilis grown at physiological temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Wall teichoic acid polymers are dispensable for cell viability in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Lesions in teichoic acid biosynthesis in Staphylococcus aureus lead to a lethal gain of function in the otherwise dispensable pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Systematic genetic analysis with ordered arrays of yeast deletion mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Combining biological networks to predict genetic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

The genetic landscape of a cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

The chemical genomic portrait of yeast: uncovering a phenotype for all genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Interaction network containing conserved and essential protein complexes in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

High-throughput, quantitative analyses of genetic interactions in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

eSGA: E. coli synthetic genetic array analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Determination of antibiotic hypersensitivity among 4,000 single-gene-knockout mutants of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

NAViGaTOR: Network Analysis, Visualization and Graphing Toronto

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Phenotypic landscape of a bacterial cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Discovery of FabH/FabF inhibitors from natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Functional classification of drugs by properties of their pairwise interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Chemical probes of Escherichia coli uncovered through chemical-chemical interaction profiling with compounds of known biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.590

Mode of action of penicillin

21 January 2018

1 reference

12 December 2020

Differential effect of mutational impairment of penicillin-binding proteins 1A and 1B on Escherichia coli strains harboring thermosensitive mutations in the cell division genes ftsA, ftsQ, ftsZ, and pbpB.

1 reference

12 December 2020

THE PUROMYCIN REACTION AND ITS RELATION TO PROTEIN SYNTHESIS

1 reference

12 December 2020

A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds

1 reference

12 December 2020

Uridine-5'-pyrophosphate derivatives. III. Amino acid-containing derivatives

1 reference

12 December 2020

Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections

1 reference

12 December 2020

Accumulation of labile phosphate in Staphylococcus aureus grown in the presence of penicillin

1 reference

12 December 2020

Uridine-5'-pyrophosphate derivatives. II. Isolation from Staphylococcus aureus

1 reference

12 December 2020

Sensitivity to Ampicillin and Cephalothin of Enzymes Involved in Wall Peptide Crosslinking in Escherichia coli K12, Strain 44

1 reference

12 December 2020

Multiple Penicillin-binding Components in Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, and Escherichia coli

1 reference

12 December 2020

SOS response as an adaptive response to DNA damage in prokaryotes

1 reference

12 December 2020

Catalysis of peptide bond formation by 50 s ribosomal subunits from Escherichia coli

1 reference

12 December 2020

The Action of Penicillin on Staphylococcus: Further Observations on the Effect of a Short Exposure

1 reference

12 December 2020

Uridine-5'-pyrophosphate derivatives. II. A structure common to three derivatives

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.590

1 reference

24 August 2017

1 reference

PubMed ID

21685879