Therapeutic applications of gold complexes: lipophilic gold(III) cations and gold(I) complexes for anti-cancer treatment (Q37889670)

24 August 2017

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title

Therapeutic applications of gold complexes: lipophilic gold(III) cations and gold(I) complexes for anti-cancer treatment (English)

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24 August 2017

1

Chi-Ming Che

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24 August 2017

Raymond Wai-Yin Sun

2

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PubMed ID

21674082

24 August 2017

language of work or name

English

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publication date

14 June 2011

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24 August 2017

Chemical Communications

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24 August 2017

47

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24 August 2017

34

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24 August 2017

9554-9560

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Gold-based therapeutic agents

24 August 2017

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Metal compounds in therapy and diagnosis

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HIV therapeutic possibilities of gold compounds

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In vitro inhibition of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase by gold(III) porphyrins

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Inhibitory effects of a new oral gold compound on hela cells

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Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.

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A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

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Mitochondrial permeability transition induced by dinuclear gold(I)-carbene complexes: potential new antimitochondrial antitumour agents.

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Gold derivatives for the treatment of cancer

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Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds

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Antitumor properties of some 2-[(dimethylamino)methyl]phenylgold(III) complexes

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Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study

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Mechanisms of cytotoxicity of selected organogold(III) compounds

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Gold(III) complexes with bipyridyl ligands: solution chemistry, cytotoxicity, and DNA binding properties

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[Au2(phen(2Me))2(μ-O)2](PF6)2, a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties

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Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to biological properties

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Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands

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Antitumor activity of gold(III)-dithiocarbamato derivatives on prostate cancer cells and xenografts

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The Midas touch in cancer chemotherapy: from platinum- to gold-dithiocarbamato complexes.

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Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway.

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A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts.

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Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity.

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Synthesis, characterization, and comparative in vitro cytotoxicity studies of platinum(II), palladium(II), and gold(III) methylsarcosinedithiocarbamate complexes

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Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties

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Metal complexes in medicine with a focus on enzyme inhibition

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Gold(III) porphyrin 1a prolongs the survival of melanoma-bearing mice and inhibits angiogenesis

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Stable anticancer gold(III)-porphyrin complexes: effects of porphyrin structure

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Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro.

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Gold (III) porphyrin complexes induce apoptosis and cell cycle arrest and inhibit tumor growth in colon cancer

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Gold(III) porphyrin complex is more potent than cisplatin in inhibiting growth of nasopharyngeal carcinoma in vitro and in vivo.

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Inhibition of Akt sensitises neuroblastoma cells to gold(III) porphyrin 1a, a novel antitumour drug induced apoptosis and growth inhibition.

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Modulation of gold(III) porphyrin 1a-induced apoptosis by mitogen-activated protein kinase signaling pathways

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Cellular pharmacological properties of gold(III) porphyrin 1a, a potential anticancer drug lead

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Gold(III) compound is a novel chemocytotoxic agent for hepatocellular carcinoma

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Proteomic characterization of the cytotoxic mechanism of gold (III) porphyrin 1a, a potential anticancer drug

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Gold(III) porphyrins as a new class of anticancer drugs: cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells.

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A gold(III) porphyrin complex with antitumor properties targets the Wnt/beta-catenin pathway

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Anticancer cyclometalated [Au(III)m(C(wedge)N(wedge)C)mL]n+ compounds: Synthesis and cytotoxic properties

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Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons

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Gold(I) complex of N,N'-disubstituted cyclic thiourea with in vitro and in vivo anticancer properties-potent tight-binding inhibition of thioredoxin reductase

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Encapsulation of dual cytotoxic and anti-angiogenic gold(III) complexes by gelatin-acacia microcapsules: in vitro and in vivo studies

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DNA binding properties of novel cytotoxic gold(III) complexes of terpyridine ligands: the impact of steric and electrostatic effects

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Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

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Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents

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Gold(III) Porphyrin 1a Induced Apoptosis by Mitochondrial Death Pathways Related to Reactive Oxygen Species

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Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

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Bioinorganic and medicinal chemistry: aspects of gold(i)-protein complexes

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21 January 2018

Identifiers

DOI

10.1039/C1CC10860C

1 reference

24 August 2017

1 reference

PubMed ID

21674082