Cisapride: what can we learn from the rise and fall of a prokinetic? (Q37880285)

24 August 2017

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title

Cisapride: what can we learn from the rise and fall of a prokinetic? (English)

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24 August 2017

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Eamonn M M Quigley

1

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24 August 2017

1 June 2011

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Journal of Digestive Diseases

24 August 2017

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24 August 2017

12

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24 August 2017

3

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24 August 2017

147-156

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Cisapride. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use as a prokinetic agent in gastrointestinal motility disorders

24 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Pharmacokinetic profile of cisapride 20 mg after once- and twice-daily dosing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Grapefruit juice-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of cisapride, a new gastrointestinal prokinetic substance, on interdigestive and postprandial motor activity of the distal oesophagus in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on the gastro-oesophageal function in normal human subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride restores the decreased lower oesophageal sphincter pressure in reflux patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of cisapride on parameters of oesophageal motility and on the prolonged intraoesophageal pH test in infants with gastro-oesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of ranitidine and cisapride on acid reflux and oesophageal motility in patients with reflux oesophagitis: a 24 hour ambulatory combined pH and manometry study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride inhibits meal-stimulated gastric acid secretion and post-prandial gastric acidity in subjects with gastro-oesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on postprandial gastro-oesophageal reflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

The effect of cisapride on oesophageal motility and lower sphincter function in patients with gastro-oesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Does the addition of a prokinetic to proton pump inhibitor therapy help reduce duodenogastro-oesophageal reflux in patients with Barrett's oesophagus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on nocturnal transient lower oesophageal sphincter relaxations and nocturnal gastro-oesophageal reflux in patients with oesophagitis: a double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on gastric sensitivity to distension, gastric compliance and duodeno-gastric reflexes in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Evaluation of gastric emptying and motility in diabetic gastroparesis with magnetic resonance imaging: effects of cisapride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of cisapride on gastric emptying of oil and aqueous meal components, hunger, and fullness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Postprandial antropyloroduodenal motility and gastric emptying in gastroparesis--effects of cisapride

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Slow gastric emptying induced by high fat content of meal accelerated by cisapride administered rectally

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Measurement of gastric emptying in dyspeptic patients: effect of a new gastrokinetic agent (cisapride)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of chronic administration of cisapride on gastric emptying of a solid meal and on dyspeptic symptoms in patients with idiopathic gastroparesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Objective and subjective results of a randomized, double-blind, placebo-controlled trial using cisapride to treat gastroparesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Long-term efficacy of oral cisapride in symptomatic upper gut dysmotility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on delayed gastric emptying in gastro-oesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Randomised controlled trial of cisapride in preterm infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

The effect of cisapride on duodenal acid exposure in the proximal duodenum in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride stimulates antral motility and decreases biliary reflux in patients with severe dyspepsia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Longterm oral cisapride improves interdigestive antroduodenal motility in dyspeptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride provides symptomatic relief in functional dyspepsia associated with gastric myoelectrical abnormality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of oral cisapride on interdigestive jejunal motor activity, psychomotor function, and side-effect profile in healthy man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride stimulates propulsive motility patterns in human jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of oral cisapride on small bowel motility in irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effects of cisapride on symptoms and postcibal small-bowel motor function in patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride in chronic idiopathic constipation: clinical response and effect on colonic transit time

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on human fasting gallbladder volume: a real-time ultrasonographic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Healing and prevention of relapse of reflux oesophagitis by cisapride

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Heartburn treatment in primary care: randomised, double blind study for 8 weeks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Maintenance therapy with cisapride after healing of erosive oesophagitis: a double-blind placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Meta-analysis of randomized controlled trials on the benefits and risks of using cisapride for the treatment of gastroesophageal reflux in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride in functional dyspepsia in general practice. A placebo-controlled, randomized, double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Symptomatic improvement with one-year cisapride treatment in neuropathic chronic intestinal dysmotility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Randomised controlled trial of cisapride in feed intolerance in preterm infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride reduces neonatal postoperative ileus: randomised placebo controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Treatment of chronic constipation with cisapride and placebo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride for the treatment of constipation in children: A double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Does cisapride influence cardiac rhythm? Results of a United States multicenter, double-blind, placebo-controlled pediatric study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Tachycardia during cisapride treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Influence of grapefruit juice on cisapride pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Block of the rapid component of the delayed rectifier potassium current by the prokinetic agent cisapride underlies drug-related lengthening of the QT interval

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Refining insights into high-affinity drug binding to the human ether-à-go-go-related gene potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Cisapride-induced transmural dispersion of repolarization and torsade de pointes in the canine left ventricular wedge preparation during epicardial stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

QTc interval in infants receiving cisapride

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Evidence of impaired cisapride metabolism in neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

A comparison of the pharmacokinetics of two dosing regimens of cisapride and their effects on corrected QT interval in premature infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Coprescribing and codispensing of cisapride and contraindicated drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Randomised double-blind comparison of simethicone with cisapride in functional dyspepsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

A comparison of two cohort studies evaluating the safety of cisapride: Prescription-Event Monitoring and a large phase IV study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

Effect of cisapride on distal colonic motility in the early postoperative period following left colonic anastomosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1751-2980.2011.00491.X

10.1111/J.1751-2980.2011.00491.X

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21615867