Integrase-defective lentiviral-vector-based vaccine: a new vector for induction of T cell immunity (Q37857291)

24 August 2017

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title

Integrase-defective lentiviral-vector-based vaccine: a new vector for induction of T cell immunity (English)

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24 August 2017

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Alessandra Rossi

7

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Roberta Bona

Roberta Bona

3

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Zuleika Michelini

Zuleika Michelini

2

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Andrea Cara

Andrea Cara

9

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Maria Blasi

Maria Blasi

4

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ORCID Public Data File 2021

author name string

Donatella Rm Negri

1

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24 August 2017

Piero Filati

5

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24 August 2017

Pasqualina Leone

6

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24 August 2017

Marina Franco

8

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24 August 2017

language of work or name

English

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publication date

25 March 2011

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Expert Opinion on Biological Therapy

24 August 2017

published in

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24 August 2017

volume

11

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24 August 2017

issue

6

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24 August 2017

page(s)

739-750

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Evaluation of the persistence of vaccine-induced protection with human vaccines

24 August 2017

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Altering the tropism of lentiviral vectors through pseudotyping

21 January 2018

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Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins

21 January 2018

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Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

21 January 2018

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Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

21 January 2018

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The genetic engineering of hematopoietic stem cells: the rise of lentiviral vectors, the conundrum of the ltr, and the promise of lineage-restricted vectors

21 January 2018

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Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization.

21 January 2018

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Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system

21 January 2018

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Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

21 January 2018

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Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

21 January 2018

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Gene therapy. As Gelsinger case ends, gene therapy suffers another blow

21 January 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Hot spots of retroviral integration in human CD34+ hematopoietic cells

21 January 2018

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Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

21 January 2018

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Immunization delivered by lentiviral vectors for cancer and infectious diseases

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A quantitative assay for HIV DNA integration in vivo

21 January 2018

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New insight on the role of extrachromosomal retroviral DNA

21 January 2018

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Retroviral E-DNA: persistence and gene expression in nondividing immune cells.

21 January 2018

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Integration-deficient lentiviral vectors: a slow coming of age.

21 January 2018

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Novel integrase-defective lentiviral episomal vectors for gene transfer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Effective gene therapy with nonintegrating lentiviral vectors

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Stable gene transfer to muscle using non-integrating lentiviral vectors

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector

21 January 2018

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Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants

21 January 2018

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Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo

21 January 2018

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Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors.

21 January 2018

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Toward integrase defective lentiviral vectors for genetic immunization.

21 January 2018

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Protective Antiviral Immunity Conferred by a Nonintegrative Lentiviral Vector-Based Vaccine

21 January 2018

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Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy

21 January 2018

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Nonintegrating lentiviral vectors can effectively deliver ovalbumin antigen for induction of antitumor immunity

21 January 2018

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Development and use of SIV-based Integrase defective lentiviral vector for immunization.

21 January 2018

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Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity

21 January 2018

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Transduction of human antigen-presenting cells with integrase-defective lentiviral vector enables functional expansion of primed antigen-specific CD8(+) T cells

21 January 2018

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Human immunodeficiency virus type 1 (HIV-1) Vpr enhances expression from unintegrated HIV-1 DNA.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Lentiviral vectors for immune cells targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Mucosal vaccines: the promise and the challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Targeting early infection to prevent HIV-1 mucosal transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Mucosal immunity and vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Proinflammatory responses in the murine brain after intranasal delivery of cholera toxin: implications for the use of AB toxins as adjuvants in intranasal vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Sublingual immunotherapy: what have we learnt from the 'big trials'?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Sublingual vaccination with influenza virus protects mice against lethal viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Lentivirus vector can be readministered to nasal epithelia without blocking immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Gene delivery to airway epithelial cells in vivo: a direct comparison of apical and basolateral transduction strategies using pseudotyped lentivirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Lentivirus-mediated gene transfer to the respiratory epithelium: a promising approach to gene therapy of cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Intratracheal administration of third-generation lentivirus vector encoding MPT51 from Mycobacterium tuberculosis induces specific CD8+ T-cell responses in the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Expression of vFLIP in a lentiviral vaccine vector activates NF-{kappa}B, matures dendritic cells, and increases CD8+ T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

HIV-1 integration as a target for antiretroviral therapy: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Specific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

HIV integrase as a target for antiviral chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Development of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Evaluation of HIV-1 integrase inhibitors on human primary macrophages using a luciferase-based single-cycle phenotypic assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Early transcription from nonintegrated DNA in human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Persistent transcription of a nonintegrating mutant of simian immunodeficiency virus in rhesus macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Human macrophages support persistent transcription from unintegrated HIV-1 DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Vpr is required for efficient Nef expression from unintegrated human immunodeficiency virus type 1 DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Expression of Nef from unintegrated HIV-1 DNA downregulates cell surface CXCR4 and CCR5 on T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.571670

10.1517/14712598.2011.571670

21 January 2018

Identifiers

DOI

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