Adjuvant properties of meningococcal outer membrane vesicles and the use of adjuvants in Neisseria meningitidis protein vaccines (Q37857249)

24 August 2017

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title

Adjuvant properties of meningococcal outer membrane vesicles and the use of adjuvants in Neisseria meningitidis protein vaccines (English)

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24 August 2017

Neisseria meningitidis

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Holly Sanders

1

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PubMed ID

21434800

24 August 2017

Ian M Feavers

series ordinal

2

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24 August 2017

1 March 2011

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Expert Review of Vaccines

24 August 2017

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24 August 2017

10

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24 August 2017

3

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24 August 2017

323-334

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24 August 2017

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Clinical evaluation of a group B meningococcal N-propionylated polysaccharide conjugate vaccine in adult, male volunteers.

21 January 2018

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Meningococcal endotoxin in lethal septic shock plasma studied by gas chromatography, mass-spectrometry, ultracentrifugation, and electron microscopy

21 January 2018

1 reference

Proteomics in gram-negative bacterial outer membrane vesicles.

21 January 2018

1 reference

Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B.

21 January 2018

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Local and systemic antibody responses in mice immunized intranasally with native and detergent-extracted outer membrane vesicles from Neisseria meningitidis

21 January 2018

1 reference

Immunogenicity, reactogenicity, and safety of a P1.7b,4 strain-specific serogroup B meningococcal vaccine given to preteens.

21 January 2018

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Immunogenicity and safety of a combination of two serogroup B meningococcal outer membrane vesicle vaccines

21 January 2018

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Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis

21 January 2018

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Serogroup B meningococcal vaccines-an unfinished story

21 January 2018

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Meningococcal surrogates of protection--serum bactericidal antibody activity

21 January 2018

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Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease

21 January 2018

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Cross-reactivity of antibodies against PorA after vaccination with a meningococcal B outer membrane vesicle vaccine

21 January 2018

1 reference

MF59™ as a vaccine adjuvant: a review of safety and immunogenicity

21 January 2018

1 reference

Prepandemic H5N1 influenza vaccine adjuvanted with AS03: a review of the pre-clinical and clinical data.

21 January 2018

1 reference

New hepatitis B vaccine formulated with an improved adjuvant system

21 January 2018

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Vaccine adjuvant systems: enhancing the efficacy of sub-unit protein antigens

21 January 2018

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Evaluation of De-O-acetylated meningococcal C polysaccharide-tetanus toxoid conjugate vaccine in infancy: reactogenicity, immunogenicity, immunologic priming, and bactericidal activity against O-acetylated and De-O-acetylated serogroup C strains

21 January 2018

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Ability of 3 different meningococcal C conjugate vaccines to induce immunologic memory after a single dose in UK toddlers.

21 January 2018

1 reference

Immunological concepts of vaccine adjuvant activity

21 January 2018

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Meningococcal vaccines and herd immunity: lessons learned from serogroup C conjugate vaccination programs.

21 January 2018

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Understanding the immune responses to the meningococcal strain-specific vaccine MeNZB measured in studies of infants.

21 January 2018

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Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity

21 January 2018

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Aluminum hydroxide adjuvant induces macrophage differentiation towards a specialized antigen-presenting cell type.

21 January 2018

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Immunization with the adjuvant MF59 induces macrophage trafficking and apoptosis

21 January 2018

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Danger - pathogen on the premises! Immunological tolerance

21 January 2018

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Toll-like receptor signalling

21 January 2018

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How Toll-like receptors signal: what we know and what we don't know

21 January 2018

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

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Delivery of foreign antigens by engineered outer membrane vesicle vaccines

21 January 2018

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Agonists of Toll-like receptors 3, 4, 7, and 9 are candidates for use as adjuvants in an outer membrane vaccine against Neisseria meningitidis serogroup B.

21 January 2018

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Role of Innate Immune Factors in the Adjuvant Activity of Monophosphoryl Lipid A

21 January 2018

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Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529.

21 January 2018

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Modification of lipid A biosynthesis in Neisseria meningitidis lpxL mutants: influence on lipopolysaccharide structure, toxicity, and adjuvant activity

21 January 2018

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E6020: a synthetic Toll-like receptor 4 agonist as a vaccine adjuvant

21 January 2018

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Intranasal immunization of mice with recombinant lipidated P2086 protein reduces nasal colonization of group B Neisseria meningitidis.

21 January 2018

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Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin

21 January 2018

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Bactericidal antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed factor H-binding protein and genetically attenuated endotoxin

21 January 2018

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Lipooligosaccharide-deficient Neisseria meningitidis shows altered pilus-associated characteristics

21 January 2018

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Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity

21 January 2018

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Use of CpG oligodeoxynucleotides as immunoprotective agents

21 January 2018

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A universal vaccine for serogroup B meningococcus

21 January 2018

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The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant.

21 January 2018

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Innate immune function of the neisserial porins and the relationship to vaccine adjuvant activity

21 January 2018

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Activation of human dendritic cells by the PorA protein of Neisseria meningitidis

21 January 2018

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The membrane expression of Neisseria meningitidis adhesin A (NadA) increases the proimmune effects of MenB OMVs on human macrophages, compared with NadA- OMVs, without further stimulating their proinflammatory activity on circulating monocytes.

21 January 2018

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Natural adjuvants: endogenous activators of dendritic cells

21 January 2018

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The immunogenicity-enhancing effect of emulsion vaccine adjuvants is independent of the dispersion type and antigen release rate--a revisit of the role of the hydrophile-lipophile balance (HLB) value

21 January 2018

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Enhanced antigen delivery via cell death induced by the vaccine adjuvants

21 January 2018

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Reactive oxygen and nitrogen species differentially regulate Toll-like receptor 4-mediated activation of NF-kappa B and interleukin-8 expression

21 January 2018

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ISCOM-based vaccines: the second decade.

21 January 2018

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Immunization with recombinant class 1 outer-membrane protein from Neisseria meningitidis: influence of liposomes and adjuvants on antibody avidity, recognition of native protein and the induction of a bactericidal immune response against meningococc

21 January 2018

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Immunization with the recombinant PorB outer membrane protein induces a bactericidal immune response against Neisseria meningitidis.

21 January 2018

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Comparison of functional immune responses in humans after intranasal and intramuscular immunisations with outer membrane vesicle vaccines against group B meningococcal disease.

21 January 2018

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Outer membrane vesicles of Neisseria lactamica as a potential mucosal adjuvant.

21 January 2018

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Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis.

21 January 2018

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Modulating the adjuvanticity of alum by co-administration of muramyl di-peptide (MDP) or Quil-A.

21 January 2018

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AFCo1, a meningococcal B-derived cochleate adjuvant, strongly enhances antibody and T-cell immunity against Plasmodium falciparum merozoite surface protein 4 and 5

21 January 2018

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Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in mice

21 January 2018

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Vaccine adjuvants revisited

21 January 2018

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Immunogenicity and structural characterisation of an in vitro folded meningococcal siderophore receptor (FrpB, FetA).

21 January 2018

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Coincorporation of LpxL1 and PagL mutant lipopolysaccharides into liposomes with Neisseria meningitidis opacity protein: influence on endotoxic and adjuvant activity

21 January 2018

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Characterization of MspA, an immunogenic autotransporter protein that mediates adhesion to epithelial and endothelial cells in Neisseria meningitidis.

21 January 2018

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Meningococcal outer membrane vesicle vaccines derived from mutant strains engineered to express factor H binding proteins from antigenic variant groups 1 and 2

21 January 2018

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Assessment of vaccine potential of the Neisseria-specific protein NMB0938.

21 January 2018

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Measuring antigen-specific bactericidal responses to a multicomponent vaccine against serogroup B meningococcus.

21 January 2018

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Phase I safety and immunogenicity study of a candidate meningococcal disease vaccine based on Neisseria lactamica outer membrane vesicles

21 January 2018

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Phase 1 first-in-human studies of the reactogenicity and immunogenicity of a recombinant meningococcal NspA vaccine in healthy adults

21 January 2018

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Neither interleukin-6 nor signalling via tumour necrosis factor receptor-1 contribute to the adjuvant activity of Alum and Freund's adjuvant

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERV.11.10

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24 August 2017

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PubMed ID

21434800