Design and development of peptides and peptide mimetics as antagonists for therapeutic intervention (Q37856278)

24 August 2017

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title

Design and development of peptides and peptide mimetics as antagonists for therapeutic intervention (English)

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24 August 2017

Jody M Mason

1

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24 August 2017

1 December 2010

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Future Medicinal Chemistry

24 August 2017

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24 August 2017

2

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24 August 2017

12

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24 August 2017

1813-1822

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Large-scale manufacture of peptide therapeutics by chemical synthesis

24 August 2017

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Synthetic therapeutic peptides: science and market

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Design strategies for anti-amyloid agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Modified-peptide inhibitors of amyloid beta-peptide polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Visualization of molecular interactions by fluorescence complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Role of hydrophobic and electrostatic interactions in coiled coil stability and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Semirational design of Jun-Fos coiled coils with increased affinity: Universal implications for leucine zipper prediction and design

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

iPEP: peptides designed and selected for interfering with protein interaction and function

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Positive aspects of negative design: simultaneous selection of specificity and interaction stability

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Selectional and mutational scope of peptides sequestering the Jun-Fos coiled-coil domain

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Exploring protein-protein interactions with phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Mirror image phage display--a method to generate D-peptide ligands for use in diagnostic or therapeutical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Mirror-image phage display: aiming at the mirror

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Yeast surface display for screening combinatorial polypeptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Microbial cell-surface display

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

An in vitro polysome display system for identifying ligands from very large peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

In vitro selection and evolution of functional proteins by using ribosome display

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Construction and analysis of high-complexity ribosome display random peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

mRNA display: diversity matters during in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Totally in vitro protein selection using mRNA-protein fusions and ribosome display

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

CIS display: In vitro selection of peptides from libraries of protein-DNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

An in vitro selection strategy for conferring protease resistance to ligand binding peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Constrained peptides as binding entities

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Peptide aptamers: powerful new tools for molecular medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Chris Lipinski discusses life and chemistry after the Rule of Five.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Peptidomimetics: Fmoc solid-phase pseudopeptide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Periodicity in alpha-helix lengths and C-capping preferences.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

N- and C-capping preferences for all 20 amino acids in alpha-helical peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

A hydrogen bond surrogate approach for stabilization of short peptide sequences in alpha-helical conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

A highly stable short alpha-helix constrained by a main-chain hydrogen-bond surrogate

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Direct inhibition of the NOTCH transcription factor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

A cell-penetrating helical peptide as a potential HIV-1 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta1-42 by mirror image phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Identification of D-peptide ligands through mirror-image phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Potent D-peptide inhibitors of HIV-1 entry

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

A designed protein with packing between left-handed and right-handed helices

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

The use of cell-penetrating peptides for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

The retro-inverso form of a homeobox-derived short peptide is rapidly internalised by cultured neurones: a new basis for an efficient intracellular delivery system.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Cell-penetrating-peptide-based delivery of oligonucleotides: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Strategies to improve plasma half life time of peptide and protein drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Oral protein delivery: a patent review of academic and industrial approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Therapeutic potential of venom peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Multifunctional nanoparticles--properties and prospects for their use in human medicine.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Therapeutic application of peptides and proteins: parenteral forever?

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Chemical biology: A Notch above other inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.259

21 January 2018

Identifiers

DOI

10.4155/FMC.10.259

1 reference

24 August 2017

1 reference

PubMed ID

21428804