Truncated somatostatin receptors as new players in somatostatin-cortistatin pathophysiology (Q37851157)

24 August 2017

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title

Truncated somatostatin receptors as new players in somatostatin-cortistatin pathophysiology (English)

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24 August 2017

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José Córdoba-Chacón

1

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24 August 2017

Manuel D Gahete

2

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24 August 2017

Mario Durán-Prado

3

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24 August 2017

Raul M Luque

4

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24 August 2017

Justo P Castaño

5

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24 August 2017

language of work or name

English

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publication date

1 March 2011

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Annals of the New York Academy of Sciences

24 August 2017

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24 August 2017

1220

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24 August 2017

6-15

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Pharmacological profile of somatostatin and cortistatin receptors

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Occurrence of two somatostatin variants in the frog brain: characterization of the cDNAs, distribution of the mRNAs, and receptor-binding affinities of the peptides

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Identification and characterization of a novel human cortistatin-like peptide

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Somatostatinergic systems in brain: networks and functions

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Cortistatin--functions in the central nervous system

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Cortistatin: not just another somatostatin analog

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Endocrine actions of cortistatin: in vivo studies

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Are somatostatin and cortistatin two siblings in regulating endocrine secretions? In vitro work ahead

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Gender-dependent role of endogenous somatostatin in regulating growth hormone-axis function in mice.

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Brain somatostatin receptors are up-regulated in somatostatin-deficient mice.

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Impairment in motor learning of somatostatin null mutant mice

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MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion

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Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland

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Evidence that a novel somatostatin receptor couples to an inward rectifier potassium current in AtT-20 cells

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The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ in coupling efficiency to adenylate cyclase and in agonist-induced receptor desensitization

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A mechanism for RNA splicing

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Identification and characterization of two novel truncated but functional isoforms of the somatostatin receptor subtype 5 differentially present in pituitary tumors

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Identification and characterization of new functional truncated variants of somatostatin receptor subtype 5 in rodents

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Analysis of canonical and non-canonical splice sites in mammalian genomes

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Mechanisms of alternative pre-messenger RNA splicing

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"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing

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Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human

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Regulation and function of somatostatin receptors

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The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling

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A potential inhibitory role for the new truncated variant of somatostatin receptor 5, sst5TMD4, in pituitary adenomas poorly responsive to somatostatin analogs

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The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization.

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Immunohistochemical distribution and subcellular localization of the somatostatin receptor subtype 1 (sst1) in the rat hypothalamus.

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Porcine somatostatin receptor 2 displays typical pharmacological sst2 features but unique dynamics of homodimerization and internalization.

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21 January 2018

Somatostatin receptors

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Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

21 January 2018

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10.1111/J.1749-6632.2011.05985.X

21 January 2018

Identifiers

DOI

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24 August 2017

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