Aging affects human B cell responses (Q37841206)

30 September 2017

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title

Aging affects human B cell responses (English)

1 reference

30 September 2017

Daniela Frasca

1

1 reference

PMCID

5560853

30 September 2017

Bonnie B Blomberg

series ordinal

2

1 reference

30 September 2017

12 February 2011

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Journal of Clinical Immunology

30 September 2017

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30 September 2017

31

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30 September 2017

3

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30 September 2017

430-435

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https://scigraph.springernature.com/pub.10.1007/s10875-010-9501-7

30 September 2017

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cites work

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The ageing B cell population: composition and function

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Immunosenescence and vaccine failure in the elderly

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1 October 2017

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1 October 2017

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B-cell diversity decreases in old age and is correlated with poor health status

1 October 2017

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1 October 2017

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Aging of the immune system as a prognostic factor for human longevity

1 October 2017

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1 October 2017

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Mechanism and regulation of class switch recombination

1 October 2017

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1 October 2017

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1 October 2017

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Aging and T-cell diversity

1 October 2017

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Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity

1 October 2017

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Antibody response to influenza vaccination in the elderly: a quantitative review

1 October 2017

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Signal transduction in the aging immune system

1 October 2017

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CD28 extinction in human T cells: altered functions and the program of T-cell senescence

1 October 2017

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Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features

1 October 2017

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1 October 2017

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Characterization of naïve, memory and effector CD8+ T cells: effect of age.

1 October 2017

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Basis for the age-related decline in intestinal mucosal immunity

1 October 2017

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1 October 2017

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Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen

1 October 2017

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Genetic alterations in the ageing immune system: impact on infection and cancer

1 October 2017

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B lymphopoiesis is active throughout human life, but there are developmental age-related changes

1 October 2017

1 reference

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Hyper-IgM syndromes: a model for studying the regulation of class switch recombination and somatic hypermutation generation

1 October 2017

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1 October 2017

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Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Aging impairs intestinal immunity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Ageing of lymphocytes and lymphocytes in the aged

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

The network and the remodeling theories of aging: historical background and new perspectives

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

The immunology of exceptional individuals: the lesson of centenarians.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Immunosenescence and mucosal immunity: significant effects of old age on secretory IgA concentrations and intraepithelial lymphocyte counts

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Changes in circulating B cells and immunoglobulin classes and subclasses in a healthy aged population

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Effect of Priming Infection on Serologic Response to Whole and Subunit Influenza Virus Vaccines in Animals

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

B-cell kinetics in humans: rapid turnover of peripheral blood memory cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Effect of age on humoral immunity, selection of the B-cell repertoire and B-cell development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Humoral and cellular immune response to influenza virus vaccination in aged humans.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Reduction in mortality associated with influenza vaccine during 1989-90 epidemic.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Efficacy of sequential annual vaccination with inactivated influenza virus vaccine

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Ageing and duodenal mucosal immunity.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Regulation of aged humoral immune defense against pneumococcal bacteria by IgM memory B cell.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

CD27(+) (memory) B cell decrease and apoptosis-resistant CD27(-) (naive) B cell increase in aged humans: implications for age-related peripheral B cell developmental disturbances.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Secretory IgA antibodies provide cross-protection against infection with different strains of influenza B virus

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

B cells in the aged: CD27, CD5, and CD40 expression

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Maintenance of serological memory by polyclonal activation of human memory B cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Characterization of antibody responses to annual influenza vaccination over four years in a healthy elderly population.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Age-dependent altered proportions in subpopulations of tonsillar lymphocytes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Quality and quantity of the humoral immune response in healthy elderly and young subjects after annually repeated influenza vaccination.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560853

Aging and Innate Immunity

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10875-010-9501-7

Clinical spectrum of X-linked hyper-IgM syndrome

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS10875-010-9501-7

Role of humoral and cell-mediated immunity in protection from influenza disease after immunization of healthy elderly

21 January 2018

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12 December 2020

Age- and tissue-specific differences in human germinal center B cell selection revealed by analysis of IgVH gene hypermutation and lineage trees

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12 December 2020

Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry

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12 December 2020

Ageing and immunity: addressing immune senescence to ensure healthy ageing

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12 December 2020

Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines

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12 December 2020

Vaccination against tetanus in the elderly: do recommended vaccination strategies give sufficient protection

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12 December 2020

Diversity of the Ig repertoire is maintained with age in spite of reduced germinal centre cells in human tonsil lymphoid tissue

1 reference

12 December 2020

B cell subpopulations separated by CD27 and crucial collaboration of CD27+ B cells and helper T cells in immunoglobulin production

1 reference

12 December 2020

Mucosal vaccination and immune responses in the elderly

1 reference

12 December 2020

10.1007/S10875-010-9501-7

Identifiers

DOI

1 reference

30 September 2017

1 reference

30 September 2017

1 reference

PMCID

5560853