TRPM2: a multifunctional ion channel for calcium signalling. (Q37816751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

TRPM2: a multifunctional ion channel for calcium signalling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author

Adriana Sumoza-Toledo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Reinhold Penner

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Reinhold Penner

series ordinal

2

1 reference

23 August 2017

language of work or name

English

0 references

publication date

6 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Journal of Physiology

1 reference

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17 January 2020

volume

589

1 reference

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17 January 2020

page(s)

1515-1525

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

Pt 7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice

17 January 2020

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Gene variation of the transient receptor potential cation channel, subfamily M, member 2 (TRPM2) and type 2 diabetes mellitus: A case-control study

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Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose

1 September 2018

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TRP channels of intracellular membranes

1 September 2018

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Mucolipins: Intracellular TRPML1-3 channels

1 September 2018

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Structure-functional intimacies of transient receptor potential channels

1 September 2018

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Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity

1 September 2018

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Acid-sensitive ion channels and receptors

1 September 2018

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TRPM2 functions as a lysosomal Ca2+-release channel in beta cells

1 September 2018

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Protons make tumor cells move like clockwork

1 September 2018

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H2O2-induced Ca2+ influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the beta-cells: involvement of TRPM2 channels

1 September 2018

1 reference

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Intracellular calcium activates TRPM2 and its alternative spliced isoforms

1 September 2018

1 reference

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Role of H(2)O(2)-activated TRPM2 calcium channel in oxidant-induced endothelial injury.

1 September 2018

1 reference

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Superoxide, NO, peroxynitrite and PARP in circulatory shock and inflammation

1 September 2018

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Divide and conquer: high resolution structural information on TRP channel fragments

1 September 2018

1 reference

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Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate

1 September 2018

1 reference

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TRPM2 variants and bipolar disorder risk: confirmation in a family-based association study.

1 September 2018

1 reference

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Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

1 September 2018

1 reference

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Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.

1 September 2018

1 reference

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Epigenetics: poly(ADP-ribosyl)ation of PARP-1 regulates genomic methylation patterns

1 September 2018

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Identification of novel sense and antisense transcription at the TRPM2 locus in cancer

1 September 2018

1 reference

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The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes

1 September 2018

1 reference

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Deep tissue injury: how deep is our understanding?

1 September 2018

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Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils

1 September 2018

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TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

1 September 2018

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TRP channels entering the structural era.

1 September 2018

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Neuronal TRP channels: thermometers, pathfinders and life-savers

1 September 2018

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A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events

1 September 2018

1 reference

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Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Transient receptor potential (TRP) cation channels: rewarding unique proteins.

1 September 2018

1 reference

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Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death

1 September 2018

1 reference

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Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.

1 September 2018

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Regulation of TRPM2 by extra- and intracellular calcium.

1 September 2018

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1 September 2018

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New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose

1 September 2018

1 reference

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TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?

1 September 2018

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CD38 and CD157 as receptors of the immune system: a bridge between innate and adaptive immunity

1 September 2018

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Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity

1 September 2018

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Subunit interaction in channel assembly and functional regulation of transient receptor potential melastatin (TRPM) channels

1 September 2018

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A review of TRP channels splicing

1 September 2018

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Extracellular-added ADP-ribose increases intracellular free Ca2+ concentration through Ca2+ release from stores, but not through TRPM2-mediated Ca2+ entry, in rat beta-cell line RIN-5F.

1 September 2018

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Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7

1 September 2018

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Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid.

1 September 2018

1 reference

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TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion

1 September 2018

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Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat beta-cell line RIN-5F.

1 September 2018

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An introduction to TRP channels

1 September 2018

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Activation of T cell calcium influx by the second messenger ADP-ribose

1 September 2018

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Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones

1 September 2018

1 reference

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Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder

1 September 2018

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Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells

1 September 2018

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Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels

1 September 2018

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Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatum.

1 September 2018

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Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

1 September 2018

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Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

1 September 2018

1 reference

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The TRPM ion channel subfamily: molecular, biophysical and functional features.

1 September 2018

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CUPpling calcium to lysosomal biogenesis.

1 September 2018

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Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.

1 September 2018

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The mitochondrial ADPR link between Ca2+ store release and Ca2+ influx channel opening in immune cells.

1 September 2018

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VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx

1 September 2018

1 reference

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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

1 September 2018

1 reference

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Flufenamic acid is a pH-dependent antagonist of TRPM2 channels

1 September 2018

1 reference

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Rapid vesicular translocation and insertion of TRP channels

1 September 2018

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Emerging roles of TRPM channels.

1 September 2018

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Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity

1 September 2018

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Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP ribose

1 September 2018

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Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia.

1 September 2018

1 reference

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Role and regulation of TRP channels in neutrophil granulocytes

1 September 2018

1 reference

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A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Innate immunity is regulated by CD38, an ecto-enzyme with ADP-ribosyl cyclase activity

1 September 2018

1 reference

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Response to ADP-ribose by activation of TRPM2 in the CRI-G1 insulinoma cell line

1 September 2018

1 reference

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Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

1 September 2018

1 reference

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NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Selective association of TRPC channel subunits in rat brain synaptosomes

1 September 2018

1 reference

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The indices of endogenous oxidative and antioxidative processes in plasma from schizophrenic patients. The possible role of oxidant/antioxidant imbalance

1 September 2018

1 reference

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Subunit composition of mammalian transient receptor potential channels in living cells

1 September 2018

1 reference

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Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

1 September 2018

1 reference

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TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells

1 September 2018

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LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Free radicals in the physiological control of cell function

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Immunocyte Ca2+ influx system mediated by LTRPC2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

CD38: a new paradigm in lymphocyte activation and signal transduction

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Activation of a novel non-selective cation channel by alloxan and H2O2 in the rat insulin-secreting cell line CRI-G1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

An introduction to free radical biochemistry

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Murine CD38: an immunoregulatory ectoenzyme.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Abnormal Electroretinogram from a Drosophila Mutant

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099011

Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow

1 September 2018

1 reference

12 December 2020

Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin

1 reference

12 December 2020

Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes

1 reference

12 December 2020

Metabolite of SIR2 reaction modulates TRPM2 ion channel

1 reference

12 December 2020

Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death

1 reference

12 December 2020

Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte

1 reference

12 December 2020

The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification

1 reference

12 December 2020

Permeating proton found guilty in compromising TRPM2 channel activity

1 reference

12 December 2020

10.1113/JPHYSIOL.2010.201855

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135052%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference