Injectable lipid emulsions-advancements, opportunities and challenges (Q37803157)

23 August 2017

Injectable lipid emulsions-advancements, opportunities and challenges (English)

1 reference

23 August 2017

Ketan Hippalgaonkar

1

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23 August 2017

Soumyajit Majumdar

series ordinal

2

1 reference

23 August 2017

Viral Kansara

series ordinal

3

1 reference

23 August 2017

language of work or name

English

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publication date

26 October 2010

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23 August 2017

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23 August 2017

11

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23 August 2017

4

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23 August 2017

1526-1540

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https://scigraph.springernature.com/pub.10.1208/s12249-010-9526-5

23 August 2017

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Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions

6 September 2017

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Pharmacokinetics, tissue distribution and safety of cinnarizine delivered in lipid emulsion

6 September 2017

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Fish oil lipid emulsions and immune response: what clinicians need to know

6 September 2017

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Fish oil-based lipid emulsions prevent and reverse parenteral nutrition-associated liver disease: the Boston experience.

6 September 2017

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Hot topics in parenteral nutrition. Rationale for using new lipid emulsions in parenteral nutrition and a review of the trials performed in adults.

6 September 2017

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SolEmuls technology: a way to overcome the drawback of parenteral administration of insoluble drugs

6 September 2017

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Immune modulation by parenteral lipid emulsions

6 September 2017

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Olive oil in parenteral nutrition.

6 September 2017

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Lipid injectable emulsions: Pharmacopeial and safety issues

6 September 2017

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Structured triglyceride emulsions in parenteral nutrition

6 September 2017

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New parenteral lipid emulsions for clinical use

6 September 2017

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25th Arvid Wretlind's Lecture--Silver anniversary, 25 years with ESPEN, the history of nutrition

6 September 2017

1 reference

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Fat-globule size in a propofol emulsion containing sodium metabisulfite

6 September 2017

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Tocol emulsions for drug solubilization and parenteral delivery

6 September 2017

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Formation and stability of nano-emulsions

6 September 2017

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SolEmuls-novel technology for the formulation of i.v. emulsions with poorly soluble drugs

6 September 2017

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Systematic characterization of oil-in-water emulsions for formulation design

6 September 2017

1 reference

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Formulation of intravenous Carbamazepine emulsions by SolEmuls® technology

6 September 2017

1 reference

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Antitumor effects and pharmacokinetics of aclacinomycin A carried by injectable emulsions composed of vitamin E, cholesterol, and PEG-lipid

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Advances in intravenous lipid emulsions

6 September 2017

1 reference

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Nitrogen sparing effect of structured triglycerides containing both medium-and long-chain fatty acids in critically ill patients; a double blind randomized controlled trial

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Fish oil emulsions: what benefits can they bring?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Clinical use of lipid emulsions

6 September 2017

1 reference

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Top ten considerations in the development of parenteral emulsions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Phytosterolemia in children with parenteral nutrition-associated cholestatic liver disease.

6 September 2017

1 reference

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Medium-chain triglycerides: an update

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

In vitro and in vivo activities of clarithromycin against Mycobacterium avium

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy

6 September 2017

1 reference

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Parenteral emulsions as drug carrier systems.

6 September 2017

1 reference

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Medium-chain triglyceride-based fat emulsions: an alternative energy supply in stress and sepsis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Improvement of paclitaxel therapeutic index by derivatization and association to a cholesterol-rich microemulsion: in vitro and in vivo studies.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Jonathan Roads Symposium Papers. History of parenteral nutrition

14 September 2017

1 reference

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Development of fat emulsions

14 September 2017

1 reference

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Parenteral use of medium-chain triglycerides: a reappraisal

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Submicron emulsions as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Influence of incorporation methods on partitioning behavior of lipophilic drugs into various phases of a parenteral lipid emulsion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

A novel in vitro release method for submicron sized dispersed systems

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Side-effect evaluation of a new diazepam formulation: venous sequela reduction following intravenous (i.v.) injection of a diazepam emulsion in rabbits.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

A new formulation of etomidate in lipid emulsion--bioavailability and venous provocation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Fat emulsion particle size: influence on the clearance rate and the tissue lipolytic activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Pharmacokinetics of two alternative dosage forms for cyclosporine: liposomes and intralipid

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

The influence of charged lipids on the flocculation and coalescence of oil-in-water emulsions. II: Electrophoretic properties and monolayer film studies

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Plasma clearance of emulsified triolein in conscious rats: effects of phosphatidylcholine species, cholesterol content and emulsion surface physical state.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effect of phospholipid emulsifiers on physicochemical properties of intravenous fat emulsions and/or drug carrier emulsions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effects of sphingomyelin and phosphatidylcholine acyl chains on the clearance of triacylglycerol-rich lipoproteins from plasma. Studies with lipid emulsions in rats

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effect of terminal heat sterilization on the stability of phospholipid-stabilized submicron emulsions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Fat emulsions containing medium chain triglycerides in patients with sepsis syndrome: effects on pulmonary hemodynamics and gas exchange

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Hydrolysis kinetics of phospholipids in thermally stressed intravenous lipid emulsion formulations

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effect of high-pressure homogenization on droplet size distribution and rheological properties of ice cream mixes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Formulation of an intravenous emulsion loaded with a clarithromycin-phospholipid complex and its pharmacokinetics in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effects of parenteral structured lipid emulsion on modulating the inflammatory response in rats undergoing a total gastrectomy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Enhancement of skin permeation of docetaxel: a novel approach combining microneedle and elastic liposomes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Pharmacokinetics and pharmacodynamics of chlorambucil delivered in parenteral emulsion

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Intravascular metabolism of fat emulsions: the Arvid Wretlind Lecture, ESPEN 1988.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Pharmacokinetics and tissue distribution of etoposide delivered in long circulating parenteral emulsion

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Plasma kinetics and uptake by the tumor of a cholesterol-rich microemulsion (LDE) associated to etoposide oleate in patients with ovarian carcinoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Dialkylphosphatidylcholine and egg yolk lecithin for emulsification of various triglycerides

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Partition of antimicrobial additives in an intravenous emulsion and their effect on emulsion physical stability

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effect of oxyethylene moieties in hydrogenated castor oil on the pharmacokinetics of menatetrenone incorporated in O/W lipid emulsions prepared with hydrogenated castor oil and soybean oil in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Intravenous itraconazole emulsions produced by SolEmuls technology

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effects of sphingomyelin on apolipoprotein E- and lipoprotein lipase-mediated cell uptake of lipid particles.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Improved oral bioavailability of cyclosporin A in male Wistar rats. Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Parenteral emulsions stabilized with a mixture of phospholipids and PEG-660-12-hydroxy-stearate: evaluation of accelerated and long-term stability

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Role of the lipid emulsion on an injectable formulation of lipophilic KW-3902, a newly synthesized adenosine A1-receptor antagonist

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Stability of drug-carrier emulsions containing phosphatidylcholine mixtures

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Effects of intravenous supplementation with alpha-tocopherol in patients receiving total parenteral nutrition containing medium- and long-chain triglycerides

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Oil components modulate physical characteristics and function of the natural oil emulsions as drug or gene delivery system

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

O/W lipid emulsions for parenteral drug delivery. III. Lipophilicity necessary for incorporation in oil particles even after intravenous injection.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

O/W lipid emulsions for parenteral drug delivery. II. Effect of composition on pharmacokinetics of incorporated drug

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Solubilization and stabilization of an anti-HIV thiocarbamate, NSC 629243, for parenteral delivery, using extemporaneous emulsions

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Local discomfort and thrombophlebitis following intravenous injection of diazepam. A comparison between a glycoferol-water solution and a lipid emulsion

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Fat emulsion as a vehicle for diazepam. A study of 9492 patients.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3011075

Triglyceride hydrolysis of soy oil vs fish oil emulsions

1 September 2018

1 reference

12 December 2020

Dissolving intravenous cyclosporin A in a fat emulsion carrier prevents acute renal side effects in the rat

1 reference

12 December 2020

Monounsaturated fatty acid-based lipid emulsions in critically ill patients are associated with fewer complications

1 reference

12 December 2020

Phosphatidylcholine composition of emulsions influences triacylglycerol lipolysis and clearance from plasma

1 reference

12 December 2020

Medium- and long-chain triglycerides have different effects on the synthesis of tumor necrosis factor by human mononuclear cells in patients under total parenteral nutrition

1 reference

12 December 2020

O/W lipid emulsions for parenteral drug delivery. IV. Changes in the pharmacokinetics and pharmacodynamics of a highly lipophilic drug, menatetrenone

1 reference

12 December 2020

Lipid emulsions of palmitoylrhizoxin: effects of composition on lipolysis and biodistribution

1 reference

12 December 2020

Preparation and evaluation of 2-(allylthio)pyrazine-loaded lipid emulsion with enhanced stability and liver targeting

1 reference

12 December 2020

Physicochemical properties of chitosan-lipid emulsions and their stability during the autoclaving process

1 reference

12 December 2020

Long circulating emulsion carrier systems for highly lipophilic drugs

1 reference

12 December 2020

Using different intravenous lipids: underutilized therapeutic approaches?

1 reference

12 December 2020

Medicare program; home health agencies: conditions of participation--HHS. Correction of final rule

1 reference

12 December 2020

Parenteral formulation of hexamethylmelamine potentially suitable for use in man

1 reference

12 December 2020

Lipid emulsions as a novel system to reduce the hemolytic activity of lytic agents: mechanism of the protective effect

1 reference

12 December 2020

Polyethylene glycol modified phospholipids stabilize emulsions prepared from triacylglycerol

1 reference

12 December 2020

1 reference

12 December 2020

Intravenous lipid dose and incidence of bacteremia and fungemia in patients undergoing bone marrow transplantation

1 reference

12 December 2020

Triglycerides in fish oil affect the blood clearance of lipid emulsions containing long- and medium-chain triglycerides in mice

1 reference

12 December 2020

Development of nonionic surfactant/phospholipid o/w emulsion as a paclitaxel delivery system

1 reference

12 December 2020

Properties of various phosphatidylcholines as emulsifiers or dispersing agents in microparticle preparations for drug carriers

1 reference

12 December 2020

Effects of cholesterol and cholesteryl oleate on lipolysis and liver uptake of triglyceride/phosphatidylcholine emulsions in rats

1 reference

12 December 2020

Pharmacokinetics of highly lipophilic antitumor agent palmitoyl rhizoxin incorporated in lipid emulsions in rats

1 reference

12 December 2020

Surface composition regulates clearance from plasma and triolein lipolysis of lipid emulsions

1 reference

12 December 2020

Submicron emulsions as drug carriers. Studies on destabilization potential of various drugs

1 reference

12 December 2020

Formulation development and antitumor activity of a filter-sterilizable emulsion of paclitaxel

1 reference

12 December 2020

Enhanced tumor delivery and antitumor activity of palmitoyl rhizoxin using stable lipid emulsions in mice

1 reference

12 December 2020

Preparation and characterization of a submicron lipid emulsion of docetaxel: submicron lipid emulsion of docetaxel

1 reference

12 December 2020

The preparation and properties of sterile intravenous emulsions

1 reference

12 December 2020

The redistribution of bulk aqueous phase phospholipids during thermal stressing of phospholipid-stabilized emulsions

1 reference

12 December 2020

Physicochemical properties of structured phosphatidylcholine in drug carrier lipid emulsions for drug delivery systems

1 reference

12 December 2020

Parenteral structured triglyceride emulsion improves nitrogen balance and is cleared faster from the blood in moderately catabolic patients

1 reference

12 December 2020

Cyclosporin A in fat emulsion carriers: experimental studies on pharmacokinetics and tissue distribution

1 reference

12 December 2020

Properties of various phospholipid mixtures as emulsifiers or dispersing agents in nanoparticle drug carrier preparations

1 reference

12 December 2020

Selective liver targeting of antivirals by recombinant chylomicrons--a new therapeutic approach to hepatitis B

1 reference

12 December 2020

Toxicity of solubilized and colloidal amphotericin B formulations to human erythrocytes

1 reference

12 December 2020

Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice

1 reference

12 December 2020

Long-circulating emulsions (oil-in-water) as carriers for lipophilic drugs

1 reference

12 December 2020

Structure and metabolic fate of triacylglycerol- and phospholipid-rich particles of commercial parenteral fat emulsions

1 reference

12 December 2020

Effects of phospholipid composition on the metabolism of triacylglycerol, cholesteryl ester and phosphatidylcholine from lipid emulsions injected intravenously in rats

1 reference

12 December 2020

Omega-3 triglycerides modify blood clearance and tissue targeting pathways of lipid emulsions

1 reference

12 December 2020

The influence of free fatty acid formation on the pH of phospholipid-stabilized triglyceride emulsions

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12 December 2020

Effects of cholesterol content on the metabolism of protein-free emulsion models of lipoproteins

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12 December 2020

Toxicity of amphotericin B emulsion to cultured canine kidney cell monolayers

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Effect of different types of total parenteral nutrition on T-lymphocyte subpopulations and NK cells

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10.1208/S12249-010-9526-5

Identifiers

DOI

1 reference

Dimensions Publication ID

23 August 2017

0 references

1 reference

23 August 2017

1 reference