Ion channels as antivirus targets (Q37801586)

23 August 2017

Ion channels as antivirus targets (English)

1 reference

23 August 2017

Xin Liang

1

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PubMed ID

20960300

23 August 2017

Zhi-Yuan Li

series ordinal

2

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23 August 2017

28 July 2010

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23 August 2017

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23 August 2017

25

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23 August 2017

4

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23 August 2017

267-280

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https://scigraph.springernature.com/pub.10.1007/s12250-010-3136-y

23 August 2017

0 references

cites work

Viroporin-mediated membrane permeabilization. Pore formation by nonstructural poliovirus 2B protein.

1 reference

https://api.crossref.org/works/10.1007%2FS12250-010-3136-Y

Full length Vpu from HIV-1: combining molecular dynamics simulations with NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12250-010-3136-Y

Vpu matchmakers as a therapeutic strategy for HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12250-010-3136-Y

Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12250-010-3136-Y

Two models of the influenza A M2 channel domain: verification by comparison

21 January 2018

1 reference

12 December 2020

The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus

1 reference

12 December 2020

ANTIVIRAL ACTIVITY OF 1-ADAMANTANAMINE (AMANTADINE).

1 reference

12 December 2020

Membrane interactions and alignment of structures within the HIV-1 Vpu cytoplasmic domain: effect of phosphorylation of serines 52 and 56

1 reference

12 December 2020

Proton transport behavior through the influenza A M2 channel: insights from molecular simulation

1 reference

12 December 2020

Exploring models of the influenza A M2 channel: MD simulations in a phospholipid bilayer

1 reference

12 December 2020

Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.

1 reference

12 December 2020

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

1 reference

12 December 2020

Biological significance of a human enterovirus B-specific RNA element in the 3' nontranslated region.

1 reference

12 December 2020

The M2 protein of influenza A virus is acylated

1 reference

12 December 2020

Understanding the mechanism of action of the anti-influenza virus drug amantadine

1 reference

12 December 2020

A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria

1 reference

12 December 2020

A tail of Tetherin: how pandemic HIV-1 conquered the world.

1 reference

12 December 2020

Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel

1 reference

12 December 2020

Evaluation of amantadine in chronic hepatitis C: a meta-analysis.

1 reference

12 December 2020

Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes

1 reference

12 December 2020

Analysis of the processing and transmembrane topology of the E2p7 protein of hepatitis C virus.

1 reference

12 December 2020

1 reference

12 December 2020

E2-p7 region of the bovine viral diarrhea virus polyprotein: processing and functional studies

1 reference

12 December 2020

Detection of ion channel activity in Xenopus laevis oocytes expressing Influenza C virus CM2 protein

1 reference

12 December 2020

How amantadine and rimantadine inhibit proton transport in the M2 protein channel

1 reference

12 December 2020

An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition

1 reference

12 December 2020

Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds

1 reference

12 December 2020

Molecular dynamics simulation of proton transport through the influenza A virus M2 channel

1 reference

12 December 2020

Palmitoylation of the influenza A virus M2 protein

1 reference

12 December 2020

Protein-protein interactions: modeling the hepatitis C virus ion channel p7.

1 reference

12 December 2020

The CM2 protein of influenza C virus is an oligomeric integral membrane glycoprotein structurally analogous to influenza A virus M2 and influenza B virus NB proteins

1 reference

12 December 2020

Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system

1 reference

12 December 2020

Model ion channels: gramicidin and alamethicin

1 reference

12 December 2020

HIV accessory genes Vif and Vpu.

1 reference

12 December 2020

Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes

1 reference

12 December 2020

Evidence that the CM2 protein of influenza C virus can modify the pH of the exocytic pathway of transfected cells.

1 reference

12 December 2020

The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences

1 reference

12 December 2020

Oligomeric organization and strain-specific proteolytic modification of the virion M2 protein of influenza A H1N1 viruses

1 reference

12 December 2020

Functional role of human immunodeficiency virus type 1 vpu.

1 reference

12 December 2020

Structural characteristics of the M2 protein of influenza A viruses: evidence that it forms a tetrameric channel

1 reference

12 December 2020

Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers

1 reference

12 December 2020

Oral delivery of peptide drugs: barriers and developments.

1 reference

12 December 2020

Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride

1 reference

12 December 2020

Palmitoylation of the influenza A virus M2 protein is not required for virus replication in vitro but contributes to virus virulence

1 reference

12 December 2020

Long alkylchain iminosugars block the HCV p7 ion channel

1 reference

12 December 2020

Chemical synthesis and single channel properties of tetrameric and pentameric TASPs (template-assembled synthetic proteins) derived from the transmembrane domain of HIV virus protein u (Vpu).

1 reference

12 December 2020

The influenza virus M2 protein cytoplasmic tail interacts with the M1 protein and influences virus assembly at the site of virus budding

1 reference

12 December 2020

The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives

1 reference

12 December 2020

Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface

1 reference

12 December 2020

The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation

1 reference

12 December 2020

Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.

1 reference

12 December 2020

Identification of a protein encoded by the vpu gene of HIV-1.

1 reference

12 December 2020

How pH opens a H+ channel: the gating mechanism of influenza A M2.

1 reference

12 December 2020

Structure of the influenza C virus CM2 protein transmembrane domain obtained by site-specific infrared dichroism and global molecular dynamics searching.

1 reference

12 December 2020

Influence of amantadine resistance mutations on the pH regulatory function of the M2 protein of influenza A viruses

1 reference

12 December 2020

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

1 reference

12 December 2020

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

1 reference

12 December 2020

Analysis of the posttranslational modifications of the influenza virus M2 protein

1 reference

12 December 2020

Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro

1 reference

12 December 2020

The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

1 reference

12 December 2020

Therapy of hepatitis C: from empiricism to eradication

1 reference

12 December 2020

Structure and mechanism of the M2 proton channel of influenza A virus

1 reference

12 December 2020

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

1 reference

12 December 2020

Antiviral activity of the interferon-induced cellular protein BST-2/tetherin

1 reference

12 December 2020

Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1.

1 reference

12 December 2020

The chemical and dynamical influence of the anti-viral drug amantadine on the M2 proton channel transmembrane domain

1 reference

12 December 2020

Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release.

1 reference

12 December 2020

Viral channel-forming proteins.

1 reference

12 December 2020

Three-dimensional Structure of the Channel-forming Trans-membrane Domain of Virus Protein “u” (Vpu) from HIV-1

1 reference

12 December 2020

Permeation and activation of the M2 ion channel of influenza A virus.

1 reference

12 December 2020

Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production

1 reference

12 December 2020

Determinants for Membrane Association and Permeabilization of the Coxsackievirus 2B Protein and the Identification of the Golgi Complex as the Target Organelle

1 reference

12 December 2020

Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication.

1 reference

12 December 2020

Novel assay for the influenza virus M2 channel activity

1 reference

12 December 2020

HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane

1 reference

12 December 2020

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

1 reference

12 December 2020

Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179.

1 reference

12 December 2020

Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue

1 reference

12 December 2020

The active oligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer.

1 reference

12 December 2020

19F NMR detection of the complex between amantadine and the receptor portion of the influenza A M2 ion channel in DPC micelles

1 reference

12 December 2020

Viral ion channels: structure and function.

1 reference

12 December 2020

Amantadine blocks channel activity of the transmembrane segment of the NB protein from influenza B.

1 reference

12 December 2020

The influenza A virus M2 channel: a molecular modeling and simulation study.

1 reference

12 December 2020

Secondary structure and tertiary fold of the human immunodeficiency virus protein U (Vpu) cytoplasmic domain in solution

1 reference

12 December 2020

Specific structural alteration of the influenza haemagglutinin by amantadine

1 reference

12 December 2020

Ion channels formed by NB, an influenza B virus protein

1 reference

12 December 2020

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells

1 reference

12 December 2020

Mechanisms of membrane permeabilization by picornavirus 2B viroporin

1 reference

12 December 2020

Mechanism of action of interferon and ribavirin in treatment of hepatitis C

1 reference

12 December 2020

Subcellular Localization and Topology of the p7 Polypeptide of Hepatitis C Virus

1 reference

12 December 2020

Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel.

1 reference

12 December 2020

Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes

1 reference

12 December 2020

Expression, purification, and activities of full-length and truncated versions of the integral membrane protein Vpu from HIV-1

1 reference

12 December 2020

Flu BM2 structure and function

1 reference

12 December 2020

Structure-function analysis of coxsackie B3 virus protein 2B.

1 reference

12 December 2020

10.1007/S12250-010-3136-Y

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

20960300