The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis (Q37798162)

23 August 2017

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis (English)

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23 August 2017

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Jérémie Sellam

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23 August 2017

Francis Berenbaum

series ordinal

2

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23 August 2017

language of work or name

English

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publication date

5 October 2010

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Nature Reviews Rheumatology

23 August 2017

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23 August 2017

6

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23 August 2017

625-635

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23 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.159

23 August 2017

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Inflammation and angiogenesis in osteoarthritis

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Interleukin-8, interleukin-10, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression levels are higher in synovial tissue from patients with rheumatoid arthritis than in osteoarthritis

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Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts

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Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease.

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Pre-B cell colony-enhancing factor/visfatin, a new marker of inflammation in rheumatoid arthritis with proinflammatory and matrix-degrading activities

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Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production.

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The sources of pain in knee osteoarthritis

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Neuropeptides in experimental and degenerative arthritis.

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Substance P-, calcitonin gene-related peptide-and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis

31 March 2020

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Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis

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Beta-endorphin, Met-enkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis

31 March 2020

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Nerve growth factor in rheumatic diseases

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The regulatory role of nerve growth factor and its receptor system in fibroblast-like synovial cells

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In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases

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Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3

31 March 2020

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Pro-MMP-9 is a specific macrophage product and is activated by osteoarthritic chondrocytes via MMP-3 or a MT1-MMP/MMP-13 cascade

31 March 2020

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Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis

31 March 2020

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Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation

31 March 2020

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Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

31 March 2020

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Synovial fluid macrophages are capable of osteoclast formation and resorption

31 March 2020

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Mature and activated osteoclasts exist in the synovium of rapidly destructive coxarthrosis

31 March 2020

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Anti-inflammatory activity of chondroitin sulfate

31 March 2020

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Targeted therapies in osteoarthritis: a systematic review of the trials on www.clinicaltrials.gov

31 March 2020

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Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.159

Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets

31 March 2020

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Anticytokine therapy for osteoarthritis: evidence to date

31 March 2020

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Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study

31 March 2020

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Interleukin-6 and high mobility group box protein-1 in synovial membranes and osteochondral fragments in equine osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.159

Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.159

Can ultrasonography improve on radiographic assessment in osteoarthritis of the hands? A comparison between radiographic and ultrasonographic detected pathology.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.159

The C-reactive protein but not erythrocyte sedimentation rate is associated with clinical severity in patients with osteoarthritis of the knee or hip.

31 March 2020

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12 December 2020

Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease

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12 December 2020

Osteoarthritis: a tale of three tissues.

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High resolution ultrasonography in detection of bone erosions in patients with hand osteoarthritis

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Osteoarthritis and rheumatoid arthritis pannus have similar qualitative metabolic characteristics and pro-inflammatory cytokine response.

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12 December 2020

Arthroscopic evaluation of post-traumatic patellofemoral chondropathy.

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12 December 2020

Characterisation of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints.

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12 December 2020

Human synovial fibroblasts coexpress IL-1 receptor type I and type II mRNA. The increased level of the IL-1 receptor in osteoarthritic cells is related to an increased level of the type I receptor

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12 December 2020

Magnetic resonance imaging-determined synovial membrane and joint effusion volumes in rheumatoid arthritis and osteoarthritis: comparison with the macroscopic and microscopic appearance of the synovium

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12 December 2020

T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis

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12 December 2020

Osteoarthritic synovial fibroblasts possess an increased level of tumor necrosis factor-receptor 55 (TNF-R55) that mediates biological activation by TNF-alpha

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12 December 2020

Synovial membrane inflammation and cytokine production in patients with early osteoarthritis

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12 December 2020

Osteoarthritis in 2007.

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12 December 2020

Synovial inflammation in patients with early osteoarthritis of the knee

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12 December 2020

Focally regulated endothelial proliferation and cell death in human synovium

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12 December 2020

Efficacy and role of topical treatment of gonarthrosis

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12 December 2020

Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium

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12 December 2020

Decreased expression of the CD3zeta chain in T cells infiltrating the synovial membrane of patients with osteoarthritis.

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12 December 2020

Ultrasound imaging for the rheumatologist VIII. Ultrasound imaging in osteoarthritis.

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12 December 2020

Cytokines and their role in the pathophysiology of osteoarthritis

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12 December 2020

Pathophysiology of joint pain

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12 December 2020

The role of inflammatory mediators on nociception and pain in arthritis

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12 December 2020

Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations

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12 December 2020

Soluble interleukin 6 (IL-6) receptor and IL-6 levels in serum and synovial fluid of patients with different arthropathies

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12 December 2020

Vascular endothelial growth factor levels in the serum and synovial fluid of patients with rheumatoid arthritis

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12 December 2020

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis

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12 December 2020

Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues

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12 December 2020

Clinical assessment of osteoarthritis in clinical trials

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2010.159

1 reference

Dimensions Publication ID

23 August 2017

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