The yin and yang of regulatory T cells and inflammation in RA. (Q37784385)

23 August 2017

title

The yin and yang of regulatory T cells and inflammation in RA. (English)

1 reference

23 August 2017

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Michael R Ehrenstein

2

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author name string

Clare A Notley

series ordinal

1

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23 August 2017

language of work or name

English

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publication date

31 August 2010

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Nature Reviews Rheumatology

23 August 2017

published in

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23 August 2017

volume

6

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23 August 2017

issue

10

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23 August 2017

page(s)

572-577

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2010.143

23 August 2017

exact match

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cites work

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

CD4+CD25high regulatory cells in human peripheral blood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

An essential role for Scurfin in CD4+CD25+ T regulatory cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Control of regulatory T cell development by the transcription factor Foxp3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Mast cells express IL-17A in rheumatoid arthritis synovium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Phenotypic and functional features of human Th17 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Precarious balance: Th17 cells in host defense.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

CTLA-4 control over Foxp3+ regulatory T cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Protein kinase C-theta mediates negative feedback on regulatory T cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-15 acts as a potent inducer of CD4(+)CD25(hi) cells expressing FOXP3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Epigenetic control of the foxp3 locus in regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Foxp3-dependent programme of regulatory T-cell differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

IL-17-producing human peripheral regulatory T cells retain suppressive function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Epigenetic mechanisms of regulation of Foxp3 expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Dicer-dependent microRNA pathway safeguards regulatory T cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Oral tolerance in the absence of naturally occurring Tregs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

ANTI-CD3 therapy expands the numbers of CD4+ and CD8+ Treg cells and induces sustained amelioration of collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Deacetylase inhibition promotes the generation and function of regulatory T cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Drug Insight: histone deacetylase inhibitor-based therapies for cutaneous T-cell lymphomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

Development, cytokine profile and function of human interleukin 17-producing helper T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2010.143

High susceptibility to collagen-induced arthritis in mice lacking IFN-gamma receptors.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20808295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Patients with relapsing-remitting multiple sclerosis have normal Treg function when cells expressing IL-7 receptor alpha-chain are excluded from the analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20808295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduced susceptibility to collagen-induced arthritis in mice deficient in IFN-gamma receptor.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20808295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRRHEUM.2010.143

1 reference

23 August 2017

1 reference