The application of metabonomics to predict drug-induced liver injury (Q37776403)

23 August 2017

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title

The application of metabonomics to predict drug-induced liver injury (English)

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23 August 2017

T M O'Connell

1

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23 August 2017

P B Watkins

series ordinal

2

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23 August 2017

language of work or name

English

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publication date

28 July 2010

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Clinical Pharmacology & Therapeutics

23 August 2017

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23 August 2017

88

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23 August 2017

3

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23 August 2017

394-399

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Using controlled clinical trials to learn more about acute drug-induced liver injury

23 August 2017

1 reference

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Monitoring for hepatotoxicity: what is the predictive value of liver "function" tests?

21 January 2018

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Biomarkers for the diagnosis and management of drug-induced liver injury

21 January 2018

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HLA-B*5701 screening for hypersensitivity to abacavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Metabonomics: a platform for studying drug toxicity and gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

21 January 2018

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Pharmaco-metabonomic phenotyping and personalized drug treatment

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The in vivo and in vitro protective properties of taurine

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https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Evidence of different metabolic phenotypes in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Human metabolic phenotype diversity and its association with diet and blood pressure.

21 January 2018

1 reference

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A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran

21 January 2018

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https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

An integrative approach for identifying a metabolic phenotype predictive of individualized pharmacokinetics of tacrolimus.

21 January 2018

1 reference

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Use of pharmaco-metabonomics for early prediction of acetaminophen-induced hepatotoxicity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Clinical pharmacokinetics of tacrolimus

21 January 2018

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Hepatic findings in long-term clinical trials of ximelagatran

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Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial

21 January 2018

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Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

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Glycine protection of PC-12 cells against injury by ATP-depletion

21 January 2018

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Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics

21 January 2018

1 reference

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Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

21 January 2018

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INTERMAP: background, aims, design, methods, and descriptive statistics (nondietary).

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Higher blood pressure in middle-aged American adults with less education-role of multiple dietary factors: the INTERMAP study

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Nutrient intakes of middle-aged men and women in China, Japan, United Kingdom, and United States in the late 1990s: the INTERMAP study.

21 January 2018

1 reference

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Susceptibility of Human Metabolic Phenotypes to Dietary Modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Individual Human Phenotypes in Metabolic Space and Time

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

Metabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects

21 January 2018

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The correlation between urinary and liver taurine levels and between pre-dose urinary taurine and liver damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

7 January 2021

Role of taurine in preventing acetaminophen-induced hepatic injury in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

7 January 2021

Metabolism and excretion of methylamines in rats

1 reference

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7 January 2021

Pharmacometabonomic phenotyping reveals different responses to xenobiotic intervention in rats

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

7 January 2021

Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

7 January 2021

Effect of glycine on valproate toxicity in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

7 January 2021

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

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Background to the INTERMAP study of nutrients and blood pressure

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.151

7 January 2021

Identifiers

DOI

10.1038/CLPT.2010.151

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release_j52x2axkmjeqpkhhthqast2vba

23 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/j52x2axkmjeqpkhhthqast2vba

24 November 2022

mapped directly with Wikidata item

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