Calcium-activated potassium channels - a therapeutic target for modulating nitric oxide in cardiovascular disease? (Q37766237)

22 August 2017

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title

Calcium-activated potassium channels - a therapeutic target for modulating nitric oxide in cardiovascular disease? (English)

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22 August 2017

cardiovascular disease

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Thomas Dalsgaard

1

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22 August 2017

Christel Kroigaard

series ordinal

2

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22 August 2017

Ulf Simonsen

series ordinal

3

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22 August 2017

language of work or name

English

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publication date

1 August 2010

1 reference

Expert Opinion on Therapeutic Targets

22 August 2017

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22 August 2017

14

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22 August 2017

8

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22 August 2017

825-837

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Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction

22 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Endothelial dysfunction: does it matter? Is it reversible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Endothelium-dependent hyperpolarizations: past beliefs and present facts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Calcium-activated potassium channels and endothelial dysfunction: therapeutic options?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Vascular KCa-channels as therapeutic targets in hypertension and restenosis disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Combination of Ca2+ -activated K+ channel blockers inhibits acetylcholine-evoked nitric oxide release in rat superior mesenteric artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Small- and intermediate-conductance Ca2+-activated K+ channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Openers of SKCa and IKCa channels enhance agonist-evoked endothelial nitric oxide synthesis and arteriolar vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Role of calcium-activated potassium channels with small conductance in bradykinin-induced vasodilation of porcine retinal arterioles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Role of the NH2 terminus in the assembly and trafficking of the intermediate conductance Ca2+-activated K+ channel hIK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Determination of the subunit stoichiometry of a voltage-activated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Characterization of an apamin-sensitive small-conductance Ca(2+)-activated K(+) channel in porcine coronary artery endothelium: relevance to EDHF

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Characterization of a charybdotoxin-sensitive intermediate conductance Ca2+-activated K+ channel in porcine coronary endothelium: relevance to EDHF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Small and intermediate conductance Ca(2+)-activated K+ channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Impaired hyperpolarization in regenerated endothelium after balloon catheter injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Effects of methyl beta-cyclodextrin on EDHF responses in pig and rat arteries; association between SK(Ca) channels and caveolin-rich domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Evidence in favor of a calcium-sensing receptor in arterial endothelial cells: studies with calindol and Calhex 231.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Mechanisms underlying epithelium-dependent relaxation in rat bronchioles: analogy to EDHF-type relaxation in rat pulmonary arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Flow-dependent increase of ICAM-1 on saphenous vein endothelium is sensitive to apamin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Role of endothelial cell hyperpolarization in EDHF-mediated responses in the guinea-pig carotid artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Molecular cloning and characterization of the intermediate-conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Caveolin, caveolae, and endothelial cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Transient receptor potential channels and caveolin-1: good friends in tight spaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Distribution, neuronal colocalization, and 17beta-E2 modulation of small conductance calcium-activated K(+) channel (SK3) mRNA in the guinea pig brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Regulation of surface localization of the small conductance Ca2+-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Protein kinase CK2 is coassembled with small conductance Ca(2+)-activated K+ channels and regulates channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Kinase-dependent regulation of the intermediate conductance, calcium-dependent potassium channel, hIK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Molecular localization of the inhibitory arachidonic acid binding site to the pore of hIK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Modulators of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels and their Therapeutic Indications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

EDHF: new therapeutic targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

NS309 restores EDHF-type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Calcium-activated potassium channels contribute to human coronary microvascular dysfunction after cardioplegic arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Store-operated calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Gating of TRP channels: a voltage connection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Expression of ryanodine receptor type 3 and TRP channels in endothelial cells: comparison of in situ and cultured human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Role of endothelial intermediate conductance KCa channels in cerebral EDHF-mediated dilations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

L-Arginine therapy in cardiovascular pathologies: beneficial or dangerous?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

L-arginine transporters in cardiovascular disease: a novel therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Alterations in rat interlobar artery membrane potential and K+ channels in genetic and nongenetic hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Large-conductance, calcium-activated potassium channels: structural and functional implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

BK channel modulators: a comprehensive overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Inhibition of vascular calcium-gated chloride currents by blockers of KCa1.1, but not by modulators of KCa2.1 or KCa2.3 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Modulation of BKCa channel gating by endogenous signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Protein kinases: tuners of the BKCa channel in smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Hydrogen peroxide, potassium currents, and membrane potential in human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Blunted acetylcholine relaxation and nitric oxide release in arteries from renal hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

LDLs impair vasomotor function of the coronary microcirculation: role of superoxide anions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Antioxidant vitamin supplements and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Selective blockade of the intermediate-conductance Ca2+-activated K+ channel suppresses proliferation of microvascular and macrovascular endothelial cells and angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Blockage of intermediate-conductance-Ca(2+) -activated K(+) channels inhibits progression of human endometrial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Identification of SK3 channel as a new mediator of breast cancer cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Evidence for Involvement of Both IK Ca and SK Ca Channels in Hyperpolarizing Responses of the Rat Middle Cerebral Artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Spatial separation of endothelial small- and intermediate-conductance calcium-activated potassium channels (K(Ca)) and connexins: possible relationship to vasodilator function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

10.1517/14728222.2010.500616

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference