Telomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications (Q37765230)

22 August 2017

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title

Telomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications (English)

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22 August 2017

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22 August 2017

Anita De Rossi

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language of work or name

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14 June 2010

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Medicinal Research Reviews

22 August 2017

21

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based on heuristic

inferred from page(s)

published in

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22 August 2017

32

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22 August 2017

2

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22 August 2017

233-253

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Telomeres shorten during ageing of human fibroblasts

22 August 2017

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Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis

21 January 2018

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A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

21 January 2018

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Specific association of human telomerase activity with immortal cells and cancer

21 January 2018

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Human telomerase RNA-protein interactions

21 January 2018

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Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

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Telomere length homeostasis requires that telomerase levels are limiting

21 January 2018

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Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants

21 January 2018

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Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

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Adult human mesenchymal stem cell as a target for neoplastic transformation

21 January 2018

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Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

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Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

21 January 2018

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hTERT antagonizes p53-induced apoptosis independently of telomerase activity.

21 January 2018

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hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.

21 January 2018

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Leukemic cells with increased telomerase activity exhibit resistance to imatinib

21 January 2018

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The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

21 January 2018

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Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

21 January 2018

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Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.

21 January 2018

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The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.

21 January 2018

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Multiple tumor suppressor pathways negatively regulate telomerase

21 January 2018

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Mechanisms of action of TGF-beta in cancer: evidence for Smad3 as a repressor of the hTERT gene

21 January 2018

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Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

21 January 2018

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The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity

21 January 2018

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Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation

21 January 2018

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The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation

21 January 2018

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IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells

21 January 2018

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Telomerase is controlled by protein kinase Calpha in human breast cancer cells

21 January 2018

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How shelterin protects mammalian telomeres

21 January 2018

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Phenotypic and functional separation of memory and effector human CD8+ T cells

21 January 2018

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Telomerase is involved in IL-7-mediated differential survival of naive and memory CD4+ T cells

21 January 2018

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TNFalpha induces rapid activation and nuclear translocation of telomerase in human lymphocytes

21 January 2018

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Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

21 January 2018

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Telomere and adaptive immunity

21 January 2018

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Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus

21 January 2018

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Mitogen-activated protein kinase cascade-mediated histone H3 phosphorylation is critical for telomerase reverse transcriptase expression/telomerase activation induced by proliferation

21 January 2018

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The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.

21 January 2018

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CD28 expression in T cell aging and human longevity.

21 January 2018

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Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance

21 January 2018

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Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones.

21 January 2018

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Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals

21 January 2018

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Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

21 January 2018

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Telomere maintenance in human B lymphocytes.

21 January 2018

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Telomere lengthening and telomerase activation during human B cell differentiation

21 January 2018

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Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

21 January 2018

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Conditional immortalization of human B cells by CD40 ligation

21 January 2018

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Human normal T lymphocytes and lymphoid cell lines do express alternative splicing variants of human telomerase reverse transcriptase (hTERT) mRNA.

21 January 2018

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Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia

21 January 2018

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Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations

21 January 2018

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Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

21 January 2018

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hTERT inhibits the Epstein-Barr virus lytic cycle and promotes the proliferation of primary B lymphocytes: implications for EBV-driven lymphomagenesis

21 January 2018

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Telomerase activity and clinical progression in chronic lymphoproliferative disorders of B-cell lineage.

21 January 2018

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A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis.

21 January 2018

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Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas

21 January 2018

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Correlation of telomerase activity with development and progression of adult T-cell leukemia.

21 January 2018

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Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia

21 January 2018

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Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia

21 January 2018

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Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells

21 January 2018

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Inactivation of hTERT transcription by Tax.

21 January 2018

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Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

21 January 2018

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Role of human T-cell leukemia virus type I Tax in expression of the human telomerase reverse transcriptase (hTERT) gene in human T-cells

21 January 2018

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HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

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Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells

21 January 2018

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Epstein-Barr virus: induction and control of cell transformation

21 January 2018

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Immortalization of immunologically committed Epstein-Barr virus-transformed human B-lymphoblastoid cell lines accompanied by a strong telomerase activity

21 January 2018

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Steps involved in immortalization and tumorigenesis in human B-lymphoblastoid cell lines transformed by Epstein-Barr virus

21 January 2018

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Sustained viral activity of epstein-Barr virus contributes to cellular immortalization of lymphoblastoid cell lines

21 January 2018

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siRNA targeting LMP1-induced apoptosis in EBV-positive lymphoma cells is associated with inhibition of telomerase activity and expression

21 January 2018

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Latent membrane protein 1 of Epstein-Barr virus activates the hTERT promoter and enhances telomerase activity in B lymphocytes

21 January 2018

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Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway.

21 January 2018

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Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf.

21 January 2018

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Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells

21 January 2018

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Epstein-Barr virus latency: LMP2, a regulator or means for Epstein-Barr virus persistence?

21 January 2018

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Epstein-Barr virus latent membrane 2A (LMP2A) down-regulates telomerase reverse transcriptase (hTERT) in epithelial cell lines

21 January 2018

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Telomere size and telomerase activity in Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cell lines

21 January 2018

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Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma

21 January 2018

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

21 January 2018

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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

21 January 2018

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Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus.

21 January 2018

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Kaposi's sarcoma-associated herpesvirus can productively infect primary human keratinocytes and alter their growth properties

21 January 2018

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Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA.

21 January 2018

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The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells

21 January 2018

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The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoter

21 January 2018

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Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.

21 January 2018

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Telomerase and cancer therapeutics

21 January 2018

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Oncogene-induced cell senescence--halting on the road to cancer

21 January 2018

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Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis.

21 January 2018

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A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphoma

21 January 2018

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Increased genomic alteration complexity and telomere shortening in B-CLL cells resistant to radiation-induced apoptosis

21 January 2018

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A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT.

21 January 2018

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The many faces of telomerase: emerging extratelomeric effects

21 January 2018

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Natural history of adult T-cell leukemia/lymphoma and approaches to therapy

21 January 2018

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Accelerated telomere shortening in ataxia telangiectasia

21 January 2018

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Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MED.20211

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release_za6jotnu7baczhoubpypparbbq

22 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/za6jotnu7baczhoubpypparbbq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

20549676

1 reference

PubMed ID

20549676