Integrative oncoproteomics strategies for anticancer drug discovery (Q37763937)

22 August 2017

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title

Integrative oncoproteomics strategies for anticancer drug discovery (English)

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22 August 2017

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Rui Liu

1

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22 August 2017

Kui Wang

2

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22 August 2017

Kefei Yuan

3

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22 August 2017

Yuquan Wei

4

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22 August 2017

Canhua Huang

5

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22 August 2017

1 June 2010

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Expert Review of Proteomics

22 August 2017

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22 August 2017

7

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22 August 2017

411-429

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22 August 2017

3

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22 August 2017

Cancer statistics, 2006

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21 January 2018

Cancer statistics, 2008

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Estimates of the cancer incidence and mortality in Europe in 2006.

21 January 2018

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21 January 2018

Cancer statistics, 2007

1 reference

Antibody microarray-based oncoproteomics

21 January 2018

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Oncoproteomics: current trends and future perspectives.

21 January 2018

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Oncoproteomics of hepatocellular carcinoma: from cancer markers' discovery to functional pathways.

21 January 2018

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High-throughput proteomics of breast carcinoma cells: a focus on FTICR-MS.

21 January 2018

1 reference

Quantitative proteomics and biomarker discovery in human cancer

21 January 2018

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Cancer proteomics--an evolving battlefield. Conference on Cancer Proteomics 2009: Mechanistic Insights, Technological Advances & Molecular Medicine

21 January 2018

1 reference

Clinical proteomics: an insight into the urinary proteome. Interview with Dr. Hassan Dihazi.

21 January 2018

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Current two-dimensional electrophoresis technology for proteomics

21 January 2018

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Proteomics in translational cancer research: toward an integrated approach

21 January 2018

1 reference

Search for the tumor-related proteins of transition cell carcinoma in Taiwan by proteomic analysis

21 January 2018

1 reference

Proteomics identification of cyclophilin a as a potential prognostic factor and therapeutic target in endometrial carcinoma

21 January 2018

1 reference

Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway

21 January 2018

1 reference

Comparative proteomics approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma

21 January 2018

1 reference

Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE): advances and perspectives

21 January 2018

1 reference

Panel of serum biomarkers for the diagnosis of lung cancer

21 January 2018

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Identification of human hepatocellular carcinoma-related biomarkers by two-dimensional difference gel electrophoresis and mass spectrometry.

21 January 2018

1 reference

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

21 January 2018

1 reference

Quantitative proteomic signature of liver cancer cells: tissue transglutaminase 2 could be a novel protein candidate of human hepatocellular carcinoma

21 January 2018

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Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC.

21 January 2018

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Two-dimensional gel electrophoresis; better than a poke in the ICAT?

21 January 2018

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Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein

21 January 2018

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A perspective on the use of iTRAQ reagent technology for protein complex and profiling studies

21 January 2018

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Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry

21 January 2018

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Differential protein expressions in renal cell carcinoma: new biomarker discovery by mass spectrometry

21 January 2018

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Element-coded affinity tags for peptides and proteins

21 January 2018

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A metal-coded affinity tag approach to quantitative proteomics

21 January 2018

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Molecular profiling of the immune response in colon cancer using protein microarrays: Occurrence of autoantibodies to ubiquitin C‐terminal hydrolase L3

21 January 2018

1 reference

Preparing multiple-reaction monitoring for quantitative clinical proteomics.

21 January 2018

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Targeted proteomic strategy for clinical biomarker discovery

21 January 2018

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Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer.

21 January 2018

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Multiple reaction monitoring of mTRAQ-labeled peptides enables absolute quantification of endogenous levels of a potential cancer marker in cancerous and normal endometrial tissues

21 January 2018

1 reference

Protein microarrays: high-throughput tools for proteomics

21 January 2018

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Protein microarrays and proteomics

21 January 2018

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Comparative application of antibody and gene array for expression profiling in human squamous cell lung carcinoma.

21 January 2018

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Identification of novel proteins associated with hepatocellular carcinomas using protein microarrays

21 January 2018

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Proteomic analysis of cellular signaling

21 January 2018

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Applying proteomics to signaling networks

21 January 2018

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Proteomic approaches to the analysis of multiprotein signaling complexes

21 January 2018

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Proteomics methods for probing molecular mechanisms in signal transduction

21 January 2018

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Regulation of androgen receptor signaling in prostate cancer

21 January 2018

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Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex

21 January 2018

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The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer

21 January 2018

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The zinc finger protein ras-responsive element binding protein-1 is a coregulator of the androgen receptor: implications for the role of the Ras pathway in enhancing androgenic signaling in prostate cancer

21 January 2018

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Cyclin G-associated kinase: a novel androgen receptor-interacting transcriptional coactivator that is overexpressed in hormone refractory prostate cancer

21 January 2018

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Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth

21 January 2018

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Regulation of interleukin-6-mediated PI3K activation and neuroendocrine differentiation by androgen signaling in prostate cancer LNCaP cells

21 January 2018

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The PI(3,5)P2 and PI(4,5)P2 interactomes

21 January 2018

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Mapping of signaling pathways by functional interaction proteomics

21 January 2018

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Urine analysis and protein networking identify met as a marker of metastatic prostate cancer.

21 January 2018

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A generic protein purification method for protein complex characterization and proteome exploration

21 January 2018

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Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer

21 January 2018

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Large-scale analysis of the yeast proteome by multidimensional protein identification technology

21 January 2018

1 reference

Surface-plasmon-resonance-based chemical proteomics: efficient specific extraction and semiquantitative identification of cyclic nucleotide-binding proteins from cellular lysates by using a combination of surface plasmon resonance, sequential elutio

21 January 2018

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Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions.

21 January 2018

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BIA/MS: interfacing biomolecular interaction analysis with mass spectrometry

21 January 2018

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Surface plasmon resonance biomolecular interaction analysis mass spectrometry. 1. Chip-based analysis

21 January 2018

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Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins

21 January 2018

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Use of surface plasmon resonance coupled with mass spectrometry reveals an interaction between the voltage-gated sodium channel type X alpha-subunit and caveolin-1.

21 January 2018

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Analysis of human urine protein biomarkers via biomolecular interaction analysis mass spectrometry

21 January 2018

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Signal transduction by growth factor receptors: signaling in an instant

21 January 2018

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Development of TGF-beta signalling inhibitors for cancer therapy

21 January 2018

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Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

21 January 2018

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Comparative proteomic analysis of cell cycle-dependent apoptosis induced by transforming growth factor-beta

21 January 2018

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Proteomic profiling of bone marrow mesenchymal stem cells upon transforming growth factor beta1 stimulation

21 January 2018

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New insights into TGF-beta-Smad signalling

21 January 2018

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Proteomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression.

21 January 2018

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Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates.

21 January 2018

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A biological approach to computational models of proteomic networks

21 January 2018

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Signal integration by JNK and p38 MAPK pathways in cancer development

21 January 2018

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Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway

21 January 2018

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Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

21 January 2018

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Integrative analysis of the cancer transcriptome

21 January 2018

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Network-based classification of breast cancer metastasis

21 January 2018

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Membrane proteins and membrane proteomics

21 January 2018

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Mammalian plasma membrane proteomics

21 January 2018

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The application of mass spectrometry to membrane proteomics

21 January 2018

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ZD1839 (IRESSA): a selective EGFR-TK inhibitor

21 January 2018

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Cancer progression is associated with increased expression of basement membrane proteins in three-dimensional in vitro models of human oral cancer.

21 January 2018

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Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B.

21 January 2018

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Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer

21 January 2018

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Tumor metastasis: mechanistic insights and clinical challenges

21 January 2018

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21 January 2018

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Comparative analysis of the membrane proteome of closely related metastatic and nonmetastatic tumor cells

21 January 2018

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Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms

21 January 2018

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Unbiased examination of changes in plasma membrane proteins in drug resistant cancer cells

21 January 2018

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The role of hypoxia-induced factors in tumor progression

21 January 2018

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Proteomic analysis of plasma membrane from hypoxia-adapted malignant melanoma

21 January 2018

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Lipid rafts in health and disease

21 January 2018

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Proteomic analysis of membrane rafts of melanoma cells identifies protein patterns characteristic of the tumor progression stage.

21 January 2018

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Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma.

21 January 2018

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PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function

21 January 2018

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Exosomes: proteomic insights and diagnostic potential

21 January 2018

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Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature

21 January 2018

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Proteomics of plasma membrane microdomains

21 January 2018

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Technologies for plasma membrane proteomics.

21 January 2018

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Interactome and interface protocol (2IP): a novel strategy for high sensitivity topology mapping of protein complexes

21 January 2018

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Affinity enrichment of plasma membrane for proteomics analysis

21 January 2018

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Proteomic analysis of integral plasma membrane proteins

21 January 2018

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A method for the comprehensive proteomic analysis of membrane proteins

21 January 2018

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Autoantibody signatures in prostate cancer

21 January 2018

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Identification of tumor antigens as potential target antigens for immunotherapy by serological expression cloning

21 January 2018

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Cancer immunomics using autoantibody signatures for biomarker discovery

21 January 2018

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Identification of tumor antigens that elicit a humoral immune response in breast cancer patients' sera by serological proteome analysis (SERPA).

21 January 2018

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Autoantibody to tumor antigen, alpha 2-HS glycoprotein: a novel biomarker of breast cancer screening and diagnosis

21 January 2018

1 reference

Proteomics-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma

21 January 2018

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Autoantibody signature in human ductal pancreatic adenocarcinoma.

21 January 2018

1 reference

Identification of IMPDH2 as a tumor-associated antigen in colorectal cancer using immunoproteomics analysis

21 January 2018

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Nanoprobe-based affinity mass spectrometry for selected protein profiling in human plasma

21 January 2018

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Affinity-based methodologies and ligands for antibody purification: advances and perspectives.

21 January 2018

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Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion

21 January 2018

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Identifying autoantibody signatures in cancer: a promising challenge.

21 January 2018

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Protein arrays as tools for serum autoantibody marker discovery in cancer

21 January 2018

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Protein microarrays for gene expression and antibody screening

21 January 2018

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Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens

21 January 2018

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Proteomics-based identification of HSP60 as a tumor-associated antigen in early stage breast cancer and ductal carcinoma in situ.

21 January 2018

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Evaluation of colon cancer-specific antigen 2 as a potential serum marker for colorectal cancer

21 January 2018

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Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

21 January 2018

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Activity-based proteomics: enzyme chemistry redux

21 January 2018

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Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs

21 January 2018

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Proteomics strategy for quantitative protein interaction profiling in cell extracts.

21 January 2018

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Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

21 January 2018

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Application of activity-based probes to the study of enzymes involved in cancer progression

21 January 2018

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A genomic and functional inventory of deubiquitinating enzymes

21 January 2018

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Ubiquitin: structures, functions, mechanisms

21 January 2018

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Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines.

21 January 2018

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A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae

21 January 2018

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Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

21 January 2018

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A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae

21 January 2018

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A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.

21 January 2018

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Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

21 January 2018

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Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases

21 January 2018

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Proteomic insights into ubiquitin and ubiquitin-like proteins.

21 January 2018

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Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

21 January 2018

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Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EPR.10.14

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22 August 2017

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