Targeting lymphocyte co-stimulation: from bench to bedside (Q37739486)

22 August 2017

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title

Targeting lymphocyte co-stimulation: from bench to bedside (English)

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22 August 2017

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Nathan J Felix

1

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22 August 2017

Anish Suri

2

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22 August 2017

Luisa Salter-Cid

3

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22 August 2017

Steven G Nadler

4

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22 August 2017

Sheila Gujrathi

5

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22 August 2017

Michael Corbo

6

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22 August 2017

Richard Aranda

7

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22 August 2017

1 November 2010

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22 August 2017

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22 August 2017

43

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22 August 2017

7

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22 August 2017

514-525

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Role of the CD28 receptor in T-cell activation

22 August 2017

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https://api.crossref.org/works/10.3109%2F08916931003674741

21 January 2018

T-cell clonal anergy.

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

A molecular perspective of CTLA-4 function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Interaction of human PD-L1 and B7-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Treatment of murine lupus with CTLA4Ig

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: twelve-month results of a phase iib, double-blind, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Abatacept inhibits progression of structural damage in rheumatoid arthritis: results from the long-term extension of the AIM trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

The clinical utility of inhibiting CD28-mediated costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Inducible costimulator is essential for collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

ICOS co-stimulatory receptor is essential for T-cell activation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Restoring function in exhausted CD8 T cells during chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Regulatory T cell expression of herpesvirus entry mediator suppresses the function of B and T lymphocyte attenuator-positive effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Identification of a novel CD160+ CD4+ T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Combined coinhibitory and costimulatory modulation with anti-BTLA and CTLA4Ig facilitates tolerance in murine islet allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

A crucial role for HVEM and BTLA in preventing intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Yin-Yang of costimulation: crucial controls of immune tolerance and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CD40/CD154 interactions at the interface of tolerance and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Platelet pro-aggregatory effects of CD40L monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

The effect of anti-CD40 ligand in immune thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Transplant tolerance in non-human primates: progress, current challenges and unmet needs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

The significance of OX40 and OX40L to T-cell biology and immune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Association of the co-stimulator OX40L with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

LIGHT costimulates CD40 triggering and induces immunoglobulin secretion; a novel key partner in T cell-dependent B cell terminal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

A TNF family member LIGHT transduces costimulatory signals into human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Lymphtoxin beta receptor-Ig ameliorates TNBS-induced colitis via blocking LIGHT/HVEM signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

IL-12-independent LIGHT signaling enhances MHC class II disparate CD4+ T cell alloproliferation, IFN-gamma responses, and intestinal graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

A role for the lymphotoxin/LIGHT axis in the pathogenesis of murine collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Herpesvirus entry mediator-Ig treatment during immunization aggravates rheumatoid arthritis in the collagen-induced arthritis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Blockade of LIGHT/HVEM and B7/CD28 signaling facilitates long-term islet graft survival with development of allospecific tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916931003674741

10.3109/08916931003674741

21 January 2018

Identifiers

DOI

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Fatcat

https://api.fatcat.wiki/v0/release/pm7cgnv7arbrpdbuy3fzm4htt4

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Fatcat

https://api.fatcat.wiki/v0/release/pm7cgnv7arbrpdbuy3fzm4htt4

mapped directly with Wikidata item

30 July 2022

based on heuristic

1 reference

https://api.fatcat.wiki/v0/release/pm7cgnv7arbrpdbuy3fzm4htt4