A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine (Q37734520)

22 August 2017

A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine (English)

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22 August 2017

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Kuen-Haur Lee

1

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22 August 2017

Hsiang-Ling Lo

2

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22 August 2017

Wan-Chun Tang

3

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22 August 2017

Heidi Hao-yun Hsiao

4

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22 August 2017

Pei-Ming Yang

5

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22 August 2017

language of work or name

English

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publication date

17 September 2014

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22 August 2017

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22 August 2017

4

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22 August 2017

6394

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

22 August 2017

start time

17 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep06394

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cites work

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MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth

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Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer

22 August 2017

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Berberine: new perspectives for old remedies.

22 August 2017

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Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation

22 August 2017

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Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma

6 September 2017

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Proteomic and redox-proteomic analysis of berberine-induced cytotoxicity in breast cancer cells

6 September 2017

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Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression.

6 September 2017

1 reference

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Specific cell cycle synchronization with butyrate and cell cycle analysis.

6 September 2017

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Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

6 September 2017

1 reference

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Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.

14 September 2017

1 reference

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Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells

14 September 2017

1 reference

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The eIF-2alpha kinases and the control of protein synthesis

14 September 2017

1 reference

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A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study.

28 September 2017

1 reference

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Genomic screening for targets regulated by berberine in breast cancer cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Berberine inhibits human colon cancer cell migration via AMP-activated protein kinase-mediated downregulation of integrin β1 signaling.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Berberine and a Berberis lycium extract inactivate Cdc25A and induce alpha-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5377252

Interactions of berberine with poly(A) and tRNA

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25227736

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25227736

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CYCLOHEXIMIDE: ASPECTS OF INHIBITION OF PROTEIN SYNTHESIS IN MAMMALIAN CELLS

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25227736

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP06394

1 reference

22 August 2017

1 reference

22 August 2017

1 reference