Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections (Q37727181)

22 August 2017

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title

Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections (English)

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22 August 2017

Liliana Rodrigues

4

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Marta Martins

Marta Martins

2

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Isabel Portugal

Isabel Portugal

6

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Diana Machado

Diana Machado

5

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Leonard Amaral

Leonard Amaral

7

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Isabel Couto

Isabel Couto

3

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Miguel Viveiros

Miguel Viveiros

1

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publication date

1 April 2010

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Expert Review of Anti-infective Therapy

22 August 2017

published in

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22 August 2017

volume

8

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22 August 2017

issue

4

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22 August 2017

page(s)

465-480

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The evolution of extensively drug resistant tuberculosis (XDR-TB): history, status and issues for global control

22 August 2017

cites work

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Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps.

21 January 2018

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Tuberculosis in New York City--turning the tide

21 January 2018

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Tuberculosis control: past 10 years and future progress

21 January 2018

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Diagnostic tools in tuberculosis. Present and future

21 January 2018

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Tuberculosis in New York city: recent lessons and a look ahead.

21 January 2018

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Multidrug-resistant tuberculosis in Lisbon, Portugal: a molecular epidemiological perspective

21 January 2018

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Genetic analysis of extensively drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal

21 January 2018

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Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of mul

21 January 2018

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Use of molecular methods to identify the Mycobacterium tuberculosis complex (MTBC) and other mycobacterial species and to detect rifampin resistance in MTBC isolates following growth detection with the BACTEC MGIT 960 system

21 January 2018

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Use of the INNO LiPA Rif.TB for detection of Mycobacterium tuberculosis DNA directly in clinical specimens and for simultaneous determination of rifampin susceptibility.

21 January 2018

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Multidrug-resistant tuberculosis (MDR-TB): epidemiology, prevention and treatment

21 January 2018

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Phenothiazines: an alternative to conventional therapy for the initial management of suspected multidrug resistant tuberculosis. A call for studies.

21 January 2018

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Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines

21 January 2018

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Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed tuberculosis

21 January 2018

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Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis

21 January 2018

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In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis

21 January 2018

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Phenothiazines: potential management of Creutzfeldt-Jacob disease and its variants

21 January 2018

1 reference

Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs

21 January 2018

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The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions

21 January 2018

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Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants

21 January 2018

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Chlorpromazine: A Drug Potentially Useful for Treating Mycobacterial Infections

21 January 2018

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Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis

21 January 2018

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"Non-Antibiotics": alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries.

21 January 2018

1 reference

Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps

21 January 2018

1 reference

Association of antipsychotic and antidepressant drugs with Q-T interval prolongation

21 January 2018

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Cardiac side effects of psychiatric drugs

21 January 2018

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Thioridazine: resurrection as an antimicrobial agent?

21 January 2018

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Phenothiazines as anti-multi-drug resistant tubercular agents.

21 January 2018

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Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping

21 January 2018

1 reference

Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis

21 January 2018

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New methods for the identification of efflux mediated MDR bacteria, genetic assessment of regulators and efflux pump constituents, characterization of efflux systems and screening for inhibitors of efflux pumps.

21 January 2018

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Mycobacterial efflux pumps and chemotherapeutic implications.

21 January 2018

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Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis

21 January 2018

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Assessment of efflux pump gene expression in a clinical isolate Mycobacterium tuberculosis by real-time reverse transcription PCR.

21 January 2018

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Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid.

21 January 2018

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Role of mycobacterial efflux transporters in drug resistance: an unresolved question

21 January 2018

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The large-conductance Ca2+-activated K+ channel is essential for innate immunity

21 January 2018

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Killing activity of neutrophils is mediated through activation of proteases by K+ flux

21 January 2018

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Membrane stabilizers inhibit potassium efflux from Staphylococcus aureus strain No. U2275.

21 January 2018

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Mechanisms of phagocytosis

21 January 2018

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Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

21 January 2018

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How Mycobacterium tuberculosis subverts host immune responses.

21 January 2018

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Active transport of Na + and K + through animal cell membranes

21 January 2018

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Life and death in the granuloma: immunopathology of tuberculosis

21 January 2018

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Inhibition of the Carpobrotus edulis methanol extract on the growth of phagocytosed multidrug-resistant Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus

21 January 2018

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Carpobrotus edulis methanol extract inhibits the MDR efflux pumps, enhances killing of phagocytosed S. aureus and promotes immune modulation

21 January 2018

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Chlorpromazine has intracellular killing activity against phagocytosed Staphylococcus aureus at clinical concentrations

21 January 2018

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Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus

21 January 2018

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New tools and emerging technologies for the diagnosis of tuberculosis: part II. Active tuberculosis and drug resistance

21 January 2018

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Newer diagnostics for tuberculosis and multi-drug resistant tuberculosis

21 January 2018

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Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

21 January 2018

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In vitro activity of thioridazine against mycobacteria

21 January 2018

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Isoniazid’s Bactericidal Activity Ceases because of the Emergence of Resistance, Not Depletion ofMycobacterium tuberculosisin the Log Phase of Growth

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERI.10.20

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22 August 2017

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