The development and function of follicular helper T cells in immune responses (Q37724577)

22 August 2017

The development and function of follicular helper T cells in immune responses (English)

1 reference

22 August 2017

4

Bernhard Ryffel

1 reference

22 August 2017

Maogen Chen

1

1 reference

22 August 2017

Zhiyong Guo

2

1 reference

22 August 2017

Weiqiang Ju

3

1 reference

22 August 2017

Xiaoshun He

5

1 reference

22 August 2017

Song Guo Zheng

6

1 reference

22 August 2017

4 June 2012

1 reference

Cellular and Molecular Immunology

22 August 2017

1 reference

22 August 2017

9

1 reference

22 August 2017

5

1 reference

22 August 2017

375-379

1 reference

https://scigraph.springernature.com/pub.10.1038/cmi.2012.18

22 August 2017

0 references

cites work

Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells

1 reference

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Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

23 August 2017

1 reference

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Follicular helper CD4 T cells (TFH)

23 August 2017

1 reference

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CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice

23 August 2017

1 reference

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Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

23 August 2017

1 reference

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Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

23 August 2017

1 reference

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Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)

23 August 2017

1 reference

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PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

23 August 2017

1 reference

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The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.

23 August 2017

1 reference

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Isolation of purified and live Foxp3+ regulatory T cells using FACS sorting on scatter plot

23 August 2017

1 reference

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Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.

23 August 2017

1 reference

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Dysregulation of germinal centres in autoimmune disease.

23 August 2017

1 reference

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Bcl6 mediates the development of T follicular helper cells

23 August 2017

1 reference

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

23 August 2017

1 reference

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IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells

23 August 2017

1 reference

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T follicular helper cells differentiate from Th2 cells in response to helminth antigens

23 August 2017

1 reference

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Follicular helper T cells: lineage and location

23 August 2017

1 reference

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Cytokine-secreting follicular T cells shape the antibody repertoire

23 August 2017

1 reference

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Follicular helper T cells are required for systemic autoimmunity

23 August 2017

1 reference

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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

23 August 2017

1 reference

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

23 August 2017

1 reference

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T follicular helper (TFH) cells in normal and dysregulated immune responses

23 August 2017

1 reference

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Germinal centres: role in B-cell physiology and malignancy

23 August 2017

1 reference

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

B cell selection and susceptibility to autoimmunity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Chemokines in the systemic organization of immunity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Inhibition of Th2 differentiation and GATA-3 expression by BCL-6

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

A chemokine-driven positive feedback loop organizes lymphoid follicles

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

SLAM family receptors and SAP adaptors in immunity.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Regulation of T follicular helper cell formation and function by antigen presenting cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Follicular helper T cells in systemic lupus erythematosus: a potential therapeutic target

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Unique gene expression program of human germinal center T helper cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000446

The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCMI.2012.18

B7RP-1 blockade ameliorates autoimmunity through regulation of follicular helper T cells

21 January 2018

1 reference

12 December 2020

B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses

1 reference

12 December 2020

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

1 reference

12 December 2020

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

1 reference

12 December 2020

Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help

1 reference

12 December 2020

Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression

1 reference

12 December 2020

The germinal center response is impaired in the absence of T cell-expressed CXCR5

1 reference

12 December 2020

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

1 reference

12 December 2020

Identifiers

DOI

10.1038/CMI.2012.18

1 reference

22 August 2017

1 reference

22 August 2017

1 reference